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University of South Florida awarded five-year, $1.35 million NIH institutional grant to train scientists in vascular inflammation and injury research

TAMPA, Fla. (Feb. 4, 2022) — The University of South Florida recently received a highly competitive National Institutes of Health (NIH) Institutional Training Grant (Award Number T32HL160529), boosting the USF Health Morsani College of Medicine’s…



TAMPA, Fla. (Feb. 4, 2022) — The University of South Florida recently received a highly competitive National Institutes of Health (NIH) Institutional Training Grant (Award Number T32HL160529), boosting the USF Health Morsani College of Medicine’s (MCOM) capacity to prepare the next generation of scientists in an emerging area of research applicable to many major diseases.

Credit: Courtesy of USF Health/University of South Florida

TAMPA, Fla. (Feb. 4, 2022) — The University of South Florida recently received a highly competitive National Institutes of Health (NIH) Institutional Training Grant (Award Number T32HL160529), boosting the USF Health Morsani College of Medicine’s (MCOM) capacity to prepare the next generation of scientists in an emerging area of research applicable to many major diseases.

The NIH’s National, Heart, Lung, and Blood Institute awarded MCOM total expected funds of $1.35 million over the next five years to support the comprehensive training of pre- and postdoctoral scientists focused on research in vascular inflammation and injury. Trainees will be selected from PhD candidates and graduates, as well as MD graduates in residency or fellowship programs related to cardiovascular sciences. They will receive stipends and financial support for attending scientific conferences.

“This is the first NIH T32 institutional training award obtained by USF’s college of medicine in the last 20 years,” said program director Sarah Yuan, MD, PhD, professor and chair of the Department of Molecular Pharmacology and Physiology. “It represents a critical step in raising our national prominence in training the next generation of translational researchers.”

Translational research is the process of efficiently moving scientific discoveries made in the laboratory into the clinic, hospital, or community to treat patients and improve health.

“Our goal is to prepare these trainees with the strong knowledge, skills and vision for leading independent research that will decipher complex cellular and molecular mechanisms and develop new diagnostic and therapeutic targets for cardiovascular disease and other conditions affected by inflammation,” said Dr. Yuan, who holds the USF Health Deriso Endowed Chair in Cardiovascular Research.

Inflammation commonly underlies the onset and progression of various diseases or injuries in multiple organs, including the heart, brain, lung, kidney, gut, and placenta. Recently, Dr. Yuan noted, this includes the discovery that vascular inflammation in response to coronavirus infection is a leading cause of severe illness and death in COVID patients.

A better understanding of the physiological processes contributing to vascular inflammation can lead to more precise and much-needed ways to diagnose, treat, and possibly prevent its harmful effects,

The new training program takes advantage of the substantial number of NIH-funded researchers recruited to MCOM under the leadership of Charles J. Lockwood, MD, senior vice president for USF Health and dean of MCOM. Many of these nationally preeminent faculty hires are experts in inflammation research and the vascular biology associated with heart, lung, neurodegenerative, or other diseases. Investment in new and renovated laboratories, and research facilities with shared, highly specialized equipment has risen along with the influx of new investigators.

Up to 25 NIH-funded faculty mentors across seven MCOM departments (Molecular Pharmacology and Physiology, Internal Medicine, Surgery, Obstetrics and Gynecology, Pediatrics, Pathology and Medical Engineering), including those affiliated with the USF Health Heart Institute, the USF Health Neuroscience Institute, and several other research centers, will mentor top students recruited to the T32 program.

“Our commitment to building the research infrastructure, expertise and curriculum needed to attract the highest caliber of faculty and academically talented students will not waver,” Dr. Lockwood said. “This new institutional training award is a tremendous addition to our growing research portfolio, one that helps feed a pipeline of diverse young scientists driven to transform meaningful discoveries into best-practice patient care. They will be well prepared to understand and help solve complex problems beyond the scope of individual disciplines or laboratories.”

The program’s curriculum is composed of rigorous courses and workshops to build competency in critical thinking and communication, an intensive hands-on research experience, and a personalized career development plan. Trainees will have access to the latest technologies, including viable human organ models to study the effects of inflammatory disease and its treatment, and high-resolution imaging techniques to see changes in blood flow, cells, proteins, and other structures within and outside the tiniest vessels.


USF Health’s mission is to envision and implement the future of health. It is the partnership of the USF Health Morsani College of Medicine, the College of Nursing, the College of Public Health, the Taneja College of Pharmacy, the School of Physical Therapy and Rehabilitation Sciences, the Biomedical Sciences Graduate and Postdoctoral Programs, and USF Health’s multispecialty physicians’ group. The University of South Florida is a high-impact global research university dedicated to student success. Over the past 10 years, no other public university in the country has risen faster in U.S. News & World Report’s national university rankings than USF. For more information, visit

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An Under-allocated Investment with Pent-Up Demand

Investors Alley
An Under-allocated Investment with Pent-Up Demand
Diamonds are a $1.2 trillion natural resource, more than silver and platinum combined….



Investors Alley
An Under-allocated Investment with Pent-Up Demand

Diamonds are a $1.2 trillion natural resource, more than silver and platinum combined. As a durable hard-asset, diamonds are just like precious metals and a reliable store of wealth. In the first part of our “Why Diamonds?” series, we shared insights on diamonds as an important feature for portfolio diversification as an uncorrelated asset. In this installment, we examine current investor sentiment and see how it will dramatically evolve over time.

To set the context, we must compare diamonds to other precious metals. Today, virtually all pensions, endowments, sovereign wealth funds, asset managers, and family offices allocate a portfolio of their portfolios to gold. A frequently cited recommendation is 5 to 10%.

Allocate Early in the Position-Building Phase

Reviewing investor holdings across commodities, a startling statistic jumps out — just 1% of diamond supply is held by investors. Yet investors hold approximately 30% of the world’s gold, 19% of silver, 17% of platinum and 15% of both palladium and rhodium.

If 15% of pent-up demand is unlocked by a market-traded diamond commodity, investor allocation could amount to $180 billion at current values from $12 billion today. Could this pent-up demand be addressed by new supply? We noticed a diminishing in global supply while prices are near an all-time low. There have been no new major mines in 20 years, and others are depleted. De Beers estimates a 1%-2% supply decline annually until 2030. Some analysts project a drop of up to 5%.

While treasured for hundreds of years, diamonds are the only top-ranked precious metal resource not commonly held by investors. Diamond Standard is unlocking the value of diamonds as an asset for the first time in the form of a secure, deliverable and easily traded product — just like gold bars. Diamond demand will build as the asset is unlocked by spot trading and new securities; increasing transparency and liquidity for institutions. Today, Diamond Standard is making the diamond market and introducing coins through an initial offering. We are purchasing diamonds through a transparent bidding process on the Diamond Standard Exchange (DSE), the first-ever loose diamond market maker. The DSE bids on millions of varieties of diamonds using an automated market-making system, adjusting bids until a statistically valid sample of diamonds can be purchased. The geological yield of this sample will be the permanent benchmark for all Diamond Standard Coins. Against this standard, anyone can verify the validity of any sample or Coin.

After the initial sale, the market price of the Coin will be established by independent trading on various digital exchanges. Like gold, there will be a daily fix, used to settle the forthcoming futures on CME Globex and options on MIAX, and to report the net-asset-value for any securities or institutional funds. As an uncorrelated and under-allocated asset, diamonds will play an important role in investor portfolios. 

Join Tim Plaehn and Jay Soloff on October 26th as they’re joined by the founder of Diamond Standard who will share how you can get started in this exciting, new alternative investment. Click here for details and to register.

An Under-allocated Investment with Pent-Up Demand
Investors Alley Staff

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Binance leads as Bitcoin exchange outflows surge

Quick Take Bitcoin market dynamics are showing a notable shift, as evidenced by the massive outflows from exchanges. According to recent data, in the span…



Quick Take

Bitcoin market dynamics are showing a notable shift, as evidenced by the massive outflows from exchanges. According to recent data, in the span of two days, exchanges experienced a substantial outflow of Bitcoin, amounting to approximately $430 million.

On Oct. 16 alone, an estimated $250 million left exchanges, followed by a subsequent $200 million on Oct. 17. Interestingly, around half of these outflows originated from Binance, one of the leading cryptocurrency exchanges globally.

Exchange Netflow: (Source: Glassnode)

These outflows signal a decrease in Bitcoin on exchanges, which has led to a consequential rise in Bitcoin’s price, from roughly $26,500 to $28,500, a significant leap within a short timeframe.

Over four days, from Oct. 14 – Oct. 17, approximately 16,000 Bitcoin have been withdrawn from exchanges. Furthermore, the total number of Bitcoin held in exchange wallets is approaching a year-to-date low, with the count nearing the 2.3 million Bitcoin mark.

Exchange Balance: (Source: Glassnode)
Exchange Balance: (Source: Glassnode)

The post Binance leads as Bitcoin exchange outflows surge appeared first on CryptoSlate.

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How a junior gold company navigates capital markets pressure

Long considered a safe haven asset, the gold market has been under scrutiny in recent years as Goldshore Resources (TSXV:GSHR) can attest.
The post How…



Although gold has long been considered a safe haven asset, the gold market itself has been under scrutiny over the past several years because of access to capital, environmental and climate change pressure and social and geopolitical risks – which Goldshore Resources (TSXV:GSHR) CEO Brett Richards says has been particularly concerning to junior mining companies.  

In an interview with The Market Herald Canada, Richards said a deteriorating capital market environment has materialized over the past 18 to 24 months as a result of global geopolitical events and hostilities, including the war between Russia and Ukraine as well as the geopolitical conflict between China and Taiwan, and now Israel and Palestine. 

“This has made a lot of investors quite apprehensive to put money into play and put money in the market for fear of a larger event that has a catastrophic impact on the capital markets,” Richards told The Market Herald Canada.  

He also explained that inflation and rising interest rates are having an impact on the capital markets. Richards said the retail scene has played such an important part in the capital markets by providing liquidity when institutions have more outflows than inflows. 

“These two factors are compounding the ability for junior mining companies, with non-cash flow producing entities, to seek development capital to continue their progress,” he explained, adding that the only strategy is to find where there are pools of capital, which are mostly in private equity firms, mid-tier and senior producers that have balance sheets that can assist the junior mining sector and advance the development in tough times.  Richards said the next catalyst will come when mid-tier mining companies start to participate in the junior mining space through joint ventures, earn-ins and partnerships, adding that these are the only kinds of capital available to the junior mining sector at the moment. 

How Goldshore Resources is navigating the market 

So where does this position a company like Goldshore Resources? Richards said the company is not unlike hundreds of other companies in the junior gold space that have faced challenges in that its share price has dropped more than 50 per cent since the start of the year, but it is working to put together enough capital to complete its short-term objectives. 

Notably, the company completed a summer field program and is working towards a preliminary economic assessment (PEA) study, which is a study that includes an economic analysis of the potential viability of mineral resources done at an early stage of a project before completing a preliminary feasibility study.  

Richards said the company has adequate cash to get through that period, but that Goldshore Resources is looking at alternative sources of capital so it can continue to advance its work on the ground. 

However, Richards explained he doesn’t foresee advancing its Moss Gold project until sometime in 2024 because of current market constraints.  

“For us, this is all about managing our cash; continuing to look for a strategic partner; and making smart decisions in difficult markets,” he said. “That’s the reality of what everybody is facing.”

Richards said the company also needs to keep the development process going but not at the expense of blowing up the cap structure. 

Goldshore Resources‘ Moss Gold Project 

Located in Northwest Ontario, the Moss Gold Project is 100 per cent owned by Goldshore Resources and has a global inferred resource estimate of 6 million ounces at 1.02 gpt.  

The project is ideally located with year-round exploration in a highly prospective area and has 30 high-priority targets identified in its 2022 program. Notably, the strike length for the Moss-type targets has expanded from 2.5 kilometres to 11 kilometres.   To date, less than 10 per cent of drilling has tested high-priority targets with significant upside potential for cobalt and copper at select targets. 

In September 2023, the company released results from its summer field program, which identified five new gold trends as well as two high-grade copper gold trends.  

Richards told The Market Herald Canada in a previous interview that the company has expanded its trend of known mineralization to more than 35 km up from just 11 km. 

“This system is much larger than we originally identified,” he said. “The trend and the parallel structures along strike are extremely encouraging.” 

Richards explained to The Market Herald Canada that the project is “quite large” and deserves capital to be developed and said the company hopes to be able to find a partner so the project can realize its full potential. 

Notably, an updated mineral resource and maiden resource estimate was completed back in May, growing the inferred resource by 44 per cent. The maiden resource estimate also grew with 24 per cent more contained gold ounces and 32 per cent more tons to 5.42 million ounces of gold at 1.03 grams per ton (g/t) gold within 163.6 million tons open pit and underground. 

In June 2023, Goldshore filed an updated technical report for the project and is advancing towards a preliminary economic assessment. High-grade shears were visible in low-grade altered wall rock, three viable process routes and varying mining scales and rates.   This makes the project a likely optimum project that will be staged hybrid rather than a simple mine-to-mill operation. 

Next catalysts for Goldshore Resources 

With the company’s primary focus now shifted to 2024, Richards told The Market Herald Canada that Goldshore Resources will be balancing dilution with what the company sees as “value-adding activities.”  

He said that although he doesn’t anticipate the company to be drilling during the winter months, Goldshore Resources will look to prepare and look to prioritize what will create the most value for the company into next year.  

“[Goldshore Resources is] actively looking for a partner that can help support this project,” Richards said. “I think we have the right strategy to weather the storm.” 

Moving into next year, the company also anticipates having its PEA ready, depending on the markets.  

Goldshore Resources management team  

Brett Richards, CEO  

Brett Richards has more than 34 years of experience in mining and metals, including mine financing and mine development. He also has experience in senior-level operations and mergers and acquisitions.  

Richards also led Banro Corp. through an operational transition as a private company through to divesting certain assets. He has also served as the former transition CEO of Roxgold (TSX:ROXG), a former senior executive of Katanga Mining (TSX:KAT) and has held former senior executive positions with Kinross Gold (TSX:K) and Co-Steel (TSX:CEI). 

Peter Flindell, vice president of exploration 

Peter Flindell has 35 years of experience in mineral exploration and feasibility studies. Notably, Flindell has led teams to discover, develop and expand several gold and copper mines across Southeast Asia, Central Asia, West Africa, Central Africa, Europe and Central America.  

Flindell also has experience in base metal and iron ore projects and spent 12 years with Newmont Mining, 11 years with Avocet Mining and eight years with Signal Delta. 

Marlis Yassin, CFO

Marlis Yassin has more than 15 years of experience working with companies in various sectors such as mining, technology and industrial products.  

Additionally, Yassin has held senior finance management positions with various public companies, such as at a large industrial products company and at mid-tier mining companies. Yassin has extensive experience at Deloitte, providing reporting, advisory and assurance services to publicly traded companies, mostly in natural resources. 

Yassin holds a bachelor of commerce degree from the University of British Columbia. 

The investment opportunity 

As it currently stands, Goldshore Resources has a share price of $0.10, which is down 84.17 per cent from its initial public offering when it began trading on the TSXV in June 2021.

That being said, however, Richards told The Market Herald Canada that the company has one of the lowest discovery costs in the sector at C$10 per ounce, including acquisition costs, which he said is below the $20-to-$25 average in the sector for finding ounces. 

“There isn’t anyone trading lower (on a per ounce basis) than we are, and I think we have one of the most prospective projects in our sector in Canada,” he said.  

Richards explained that Goldshore Resources has the potential to grow the resource “exponentially,” to 15 million to 20 million ounces with 60,000 or 70,000 metres of drilling. 

“The prize, at the end of the day, is not only [the company’s] starting point, but where we can potentially get to. The Moss Gold deposit will host a mine one day, our role is defining and shaping what the resource looks like that takes us there,” he said. 

When it comes to its goals for 2024, Richards said the company will be “preparing the company” for when the market eventually turns around, adding that investors will get the largest and best return from a company like Goldshore Resources. 

In line with this, he explained that the company’s peers are trading at five or six times of what the company is on a per-ounce basis. 

“When this market turns – and it will – and when the U.S. dollar starts to weaken – and it will – we are going to see a higher gold price environment, and we are going to see activity in our space to invest with companies who can deliver the best return, and that’s Goldshore,” he said. 

Despite challenges in the market, and as Goldshore Resources looks to carefully execute its goals into 2024 and beyond, investors will be keen to watch how this undervalued company will impact the gold sector. 

Join the discussion: Find out what everybody’s saying about this stock on the Goldshore Resources Bullboard, and check out the rest of Stockhouse’s stock forums and message boards.

The material provided in this article is for information only and should not be treated as investment advice. For full disclaimer information, please click here.

The post How a junior gold company navigates capital markets pressure appeared first on The Market Herald Canada.

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