This Week in Apps: Google Play slashes commissions, Apple sued over scammy apps, YouTube launches a TikTok clone in the US
Welcome back to This Week in Apps, the weekly TechCrunch series that recaps the latest in mobile OS news, mobile applications and the overall app economy. The app industry is as hot as ever, with a record 218 billion downloads and $143 billion in…
Welcome back to This Week in Apps, the weekly TechCrunch series that recaps the latest in mobile OS news, mobile applications and the overall app economy.
The app industry is as hot as ever, with a record 218 billion downloads and $143 billion in global consumer spend in 2020.
Consumers last year also spent 3.5 trillion minutes using apps on Android devices alone. And in the U.S., app usage surged ahead of the time spent watching live TV. Currently, the average American watches 3.7 hours of live TV per day, but now spends four hours per day on their mobile devices.
Apps aren’t just a way to pass idle hours — they’re also a big business. In 2019, mobile-first companies had a combined $544 billion valuation, 6.5x higher than those without a mobile focus. In 2020, investors poured $73 billion in capital into mobile companies — a figure that’s up 27% year-over-year.
This week, there was a lot of headline-making app ecosystem news, including Google’s impactful decision to drop its Play Store commissions, an App Store lawsuit over scammy apps with fake ratings, battles over Apple’s App Tracking Transparency and the arrival of a notable new feature on YouTube — a TikTok rival called Shorts.
Developer sues Apple over lost revenue due to App Store scams
Image Credits: TechCrunch
Kosta Eleftheriou, a co-founder of the Fleksy keyboard app, has been raising awareness about App Store scams in recent weeks, after his own app was targeted by copycat subscription scammers leveraging fake ratings and reviews to gain traction. This week, Eleftheriou filed a lawsuit that attempts to hold Apple accountable for his own app’s lost revenue, saying that Apple promises developers a safe and trustworthy marketplace, but then allows these scammers to operate to the detriment of legitimate apps like his own. Though some news articles positioned the case as some sort of antitrust lawsuit, it’s really more focused on scammers and the accountability Apple has for how its App Store operates, which apps are listed and how well it’s managed and policed. Eleftheriou is asking Apple to compensate him for his lost revenue and other damages as a result of Apple’s ill-run app marketplace, as well as what he claims are unfair App Review rejections.
Google Play drops commissions to 15% on some earnings
Google Play Store screen
Google has followed Apple’s lead in reducing commissions for the Google Play store. But in its case, it has dropped commissions from 30% to 15% on developers’ first $1 million in revenue. Apple, by comparison, starts charging 30% once the developer tops $1 million. Google said 99% of developers who sell goods and services through the Play Store will see a 50% reduction in fees. According to App Annie data, very few Google Play developers make more than $1 million — in fact, only 2,035 developers do on Google Play, compared with 3,611 on iOS. To put this in perspective in terms of revenue, developers making up to $1 million in consumer spend only comprised 5% of total Google Play consumer spend in 2020, the firm noted.
Apple fended off an attempt by advertisers in France who wanted to derail the IDFA change in iOS, which will require users’ permission in order to track them. The complaint had attempted to contrast Apple’s ATT (App Tracking Transparency) requirements for third parties with Apple’s own, where its first-party apps are allow to track by default for the purpose of personalizing ads in various Apple apps. France’s competition regulator decided Apple’s plans “don’t appear to be abusive” and said it can’t intervene just because some apps may see a negative impact. But the authority did say it will investigate Apple further to determine if any of its changes are “self-preferencing.”
YouTube launches its TikTok rival in the U.S.
Image Credits: YouTube
The short-form video experience known as YouTube Shorts first launched in India, where TikTok has been banned, in September. It’s now coming to the U.S. in its first major expansion. The feature, still in beta, offers a very TikTok-like experience both in terms of recording content and viewing. Users can tap to record video segments for up to 60-second long videos, and use a small handful of editing features like text captions, countdown timers and speed controls. Meanwhile, viewing the videos is also presented in a TikTok-like format with vertical feeds of video where you can double-tap to like, duck into comments or tap on hashtags or sounds to participate in trends.
YouTube believes the feature has potential because it’s connected to the larger YouTube ecosystem, including YouTube Music and the main platform itself — you can subscribe to YouTube channels right from Shorts, for example. But Shorts lacks a lot of what makes TikTok successful for the time being, like its numerous AR effects and editing tools, sound sync and its ability for creators to react and respond to other videos through stitches and duets.
Weekly News
Platforms: Apple
Apple will allow the Russian government to pre-install apps on the iPhone starting on April 1, 2021. In accordance with a new law, Apple users will be shown a dialog box at setup that prompts them to install web browsers, antivirus, messenger and email apps. Users can choose to deselect these apps or delete them from the device later.
Report claims Apple may soon deliver standalone iOS security updates. According to code found in the latest iOS 14.5 beta, Apple could be preparing to introduce a way to update older iPhones with critical security updates without requiring users to download new versions of iOS. This could be helpful in patching older devices where users don’t download iOS updates for fear of slowing down their phone.
Apple says the App Store now supports 300K jobs in the U.K., up 10% YoY, as well as 250K jobs in Germany and another 250K in France. The figures were released in response to increased antitrust scrutiny by regulators, as a way to demonstrate the App Store’s contribution to local economies.
Platforms: Google
Image Credits: App Annie
App Annie data shows how few Google Play developers will pay the higher 30% commission after the policy change, announced this week. Google says developers’ first $1 million in revenue will be commissioned at 15%, not 30%. This covers the vast majority of the Play Store’s developer base, as only 2,035 developers make $1 million or more.
Google updates its People API, which will replace the Contacts API being deprecated on June 15, 2021. The new API will now support two new endpoints for batch mutates and Contacts searches, the company said.
Google updates its parental controls for Android, Family Link. The updates acknowledge that not all screen time is the same, by allowing parents to set some apps — like those used for virtual school — as “always allowed” and not counting toward daily limits. It also updated reporting to better show where kids were spending time outside of these necessary apps.
Google is now allowing third-party developers to build Tiles for Wear OS smartwatches. Tiles are small, fast-loading experiences that can deliver specific, timely information users need, but can be tapped to open a related app on the watch or phone for a deeper experience.
Image Credits: Google
E-commerce
Facebook’s Mark Zuckerberg said his company has been preparing for the Apple IDFA changes by investing in more commerce products on its own platforms, like Facebook and Instagram Shops. In a Clubhouse session on Thursday, he announced Facebook has 1 million active Shops which are used by 250 million people every month.
Social
Twitter is testing a way for users to watch YouTube videos from within the home timeline directly on iOS devices, instead of being redirected to YouTube. Finally! The test was made possible through YouTube’s iFrame Player API, which Twitter gained access to.
TikTok will no longer allow users to opt out of personalized advertising starting on April 15th. The app alerted users to the change via a notice that appeared on screen at launch. This means uses will see ads based on what they watch and engage with on TikTok.
TikTok may add a group chats feature sometime early this year,according to Reuters. The feature is already a part of the Chinese version of the TikTok app, Douyin, and would make the app more social.
Instagram adds new teen safety tools as competition with TikTok heats up. TikTok has been making its app safer for teens and this week Instagram followed suit — but instead of locking down teens accounts by default, it made it more difficult for adult predators to reach teens on Instagram, through a variety of alerts and blocking features.
Leaked recordings detail conservative donor Rebekah Mercer’s role at right-wing social app Parler, where she joined meetings to rally employees to fight against the shut down of free speech, and other matters, Bloomberg reports.
Facebook is preparing to add an age-gate to Instagram that would allow for a curated, and likely COPPA-compliant, under 13 experience, according to a report from BuzzFeed. TikTok today does the same thing, following its FTC fines. Instagram could be doing the same to ward off any FTC investigation into underage use of its app as well as to better cater to the younger users who are already on Instagram today.
China banned Signal. The encrypted messaging app became unavailable on the mainland on March 16, following a ban of the Signal website the day prior. The app had been one of the few Western social networks that was accessible in China without a VPN.
Telegram is working on an audio experience that allows users to create voice chats in Telegram Channels that you can join either with your personal profile or channel profile. The feature is in beta testing and no official announcement has been made.
Clubhouse hires Instagram alum Fadia Kader as its new head of Media Partnerships and Creators. The hire follows that of OWN and Netflix alum Maya Watson to serve as head of Global Marketing, and points to an increased interest in establishing Clubhouse in the world of media. Kader’s background is in music and tech, having led music partnerships at Twitter, and having worked at Def Jam.
Clubhouse promises its accelerator participants either brand deals or $5,000 per month during its three-month program. The company plans to work with around 20 creators to help them produce, book guests and promote their shows on the platform, as well as source brand deals.
Clubhouse is also currently being investigated by France’s privacy watchdog, CNIL, in an attempt to determine whether or not GDPR will apply to the app and how it’s complying with EU rules. Germany’s regulator last month was doing something similar, as it began looking into how the app was protecting the privacy of European users and their contacts.
Premium content, entertainment and streaming have helped drive up the prices of in-app purchases (IAPs). In 2020, the median price for IAPs among the top non-game apps was $5.99, up from $3.99 in 2017. The median price of subscription IAPs alone, meanwhile, has remained flat at $9.99 over the past four years, Sensor Tower found.
AT&T will begin counting HBO Max streams through the app against data limits. The company owns HBO via WarnerMedia and was previously exempting streams from data caps, but says a California net neutrality law will now no longer allow it to do so. AT&T spoke out against a patchwork of state regulations for net neutrality, saying they will create roadblocks to pro-consumer solutions.
Gaming
Image Credits: Sensor Tower
U.S. mobile puzzle game spending jumped 30% YoY to $4.6 billion in 2020, per a Sensor Tower report. The pandemic likely contributed to the rise, with top game Candy Crush Saga pulling in $643 million following by Homescapes and Gardenscapes.
Health & Fitness
Apple Maps has been updated with COVID-19 vaccine locations in the U.S. Apple is sourcing data from VaccineFinder, an initiative led by Boston Children’s Hospital, which is also one of the sources Google Maps is using. Apple is allowing healthcare providers, labs and other businesses to submit their information about vaccine locations.
Facebook will label all COVID-19 vaccine posts with a pointer to official, authoritative sources of information across Facebook and Instagram. It also said it will reduce the distribution of content from users who repeatedly violated policies on vaccine misinformation or who shared debunked claims, as well as any claims that fact checkers say are “Missing Context.”
Facebook expands support for security keys to mobile users on iOS and Android. The social network has supported the use of security keys, which generate encrypted, one-time security codes, for desktop users since 2017.
California passed new regulations that ban so-called “dark patterns,” or designs used by websites and apps to frustrate or trick users into doing things they wouldn’t normally do — like subscribing to a service they didn’t want or opting-in to sharing their data with the company, for example.
An iPhone app privacy report from cloud storage company pCloud showed how much personal data is being accessed by apps. The apps collecting the most data were Facebook and Instagram, while Klarna and Grubhub tied for second place, followed by Uber and Uber Eats.
Big tech, including Apple and Google, are ramping up their lobbying in U.S. state capitals, reports The WSJ, as a number of bills that could regulate their industries are arriving in state legislatures. One of these is an app store payments bill that is going to be debated in Arizona’s Senate in the next several weeks. If passed, developers would be able to use their own payment systems for in-app purchases instead of Apple’s and Google’s systems. Other legislation is being proposed in states including Maryland and Virginia.
A government-backed consortium of Chinese companies introduced a new method for tracking iPhone users as an alternative to IDFA (paywalled source: FT). The system could be a workaround for Apple’s App Tracking Transparency, as it won’t require user permission. Tencent and ByteDance are reportedly testing the system, known as CAID.
Google finally rolls out iOS privacy labels for Chrome and Google Search. Competitor DuckDuckGo trolled the company for its delay, saying “after months of stalling, Google finally revealed how much personal data they collect in Chrome and the Google app. No wonder they wanted to hide it.” Burn!
After months of stalling, Google finally revealed how much personal data they collect in Chrome and the Google app. No wonder they wanted to hide it. ⁰ Spying on users has nothing to do with building a great web browser or search engine. We would know (our app is both in one). pic.twitter.com/lJBbLTjMuu
App Annie partners with Snowflake and introduces a new Salesforce integration. The former allow data teams to access and transform a variety of mobile estimates, both live and continually updated. The new App Annie Intelligence Salesforce Connector, meanwhile, lets App Annie customers build a better pipeline through mobile-metric enriched CRM records.
Google Meet rolls out the tile view on iOS, to be soon followed by Android support. This view allows a user to see more of the people on the video call, even on the small screen. The app also introduced support for live captions in four new languages on mobile (French, German, Portuguese and Spanish, the latter for Spain and Latin America)
Funding and M&A
Snap acquired a Berlin-based clothing size recommendation engine Fit Analytics that helps online shoppers buy the right sized clothes. Deal terms were undisclosed. The acquisition will see over 100 Fit team members joining Snap as the company pushes into e-commerce.
Riva Health raised $15.5 million in seed (!!) funding to turn your smartphone into a blood pressure monitor, in a round led by Menlo Ventures. The company is co-founded by scientist Tuhin Sinha and Siri and Viv (exited to Samsung) co-founder Dag Kittlaus. The system being developed would have users place their finger over the phone’s camera light, which would then flash, allowing the app to use the light to track the blood pressure reading.
Mobile banking app Kuda raised $25 million led by Valar to become the neobank for all of Africa. The company today offers mobile-first banking services in Nigeria and has doubled its user base from its seed round to now 650,000.
London-based mobile investing app Invstr raised $20 million to pair Robinhood-like commission-free stock trades with digital banking services and educational and learning tools. The app has over 1 million global users.
Investing app Gatsby raised a $10 million Series A for its Robinhood competitor. The app is aimed at younger users, offering commission-free options and stock trading and is aiming to have more than 100K accounts by the end of the year.
Digitail’s app for veterinary surgery practices raised $2.5 million in seed funding, in a round led by byFounders and Gradient Ventures (Google’s AI fund). The company currently has 2,000 vets in 16 countries using its services.
Match Group makes a seven-figure investment in background check nonprofit Garbo. The Tinder parent company plans to integrate its apps with Garbo’s tools, which alert users to background checks of concern to daters like assault or stalking charges, among other things.
Telegram is selling more than $1 billion in debt to investors to fund its operations and pay creditors, with the promises of discounted equity if the company later goes public. The messaging app owes its creditors around $700m by the end of April, The WSJ reported.
Downloads
Swell
Image Credits: Swell
A new startup called Swell has a different take on voice conversations than Clubhouse. Instead of real-time conversations, Swell users engage in asynchronous chats where one user posts an audio clip of up to five minutes in length that others can listen to and then respond to with their own recording. These mini-podcasts can be private chats or public conversations. Swell is available as a free download on both iOS and Android.
1v1Me launches its app that lets anyone gamble on their ability to win in a player versus player game. The iOS app is now available in an invite-only mode, with the first invites going to creators who play games like Call of Duty and Fortnite — the first games that will be supported on the betting platform. Users can sign up for early access on the company’s website for the time being, then stalk the company on Twitter for invites.
This clever iOS recipes app, Half Lemons, does that thing you’ve always wanted a recipe app to do: it serves up dish ideas using the ingredients you have at home. To use the app, you take a quick digital inventory of your kitchen in order to customize the app to deliver recipes that are specifically tailored to your own ingredients. You can then save or share the recipes, in addition to making them right away with a screen that stays powered on as you cook. Future versions of the app will help you shop for ingredients and plan meals.
Bored with your iOS 14 customizations? Take your iPhone old-school with this super retro iOS 14 icon and wallpaper set featuring over 110 Mac OS ’84 icons and six monochromatic wallpapers. The set has been handcrafted by freelance digital product designer Ben Vessey, who many years ago had created a similar theme for “retrofying” your desktop screen. When he heard about the Shortcuts feature in iOS 14, he got to work to build a version of this retro experience for iPhone. The pack is £3.99, or £79.99 if you want to request five custom icons of your choice in addition.
Chronic stress and inflammation linked to societal and environmental impacts in new study
From anxiety about the state of the world to ongoing waves of Covid-19, the stresses we face can seem relentless and even overwhelming. Worse, these stressors…
From anxiety about the state of the world to ongoing waves of Covid-19, the stresses we face can seem relentless and even overwhelming. Worse, these stressors can cause chronic inflammation in our bodies. Chronic inflammation is linked to serious conditions such as cardiovascular disease and cancer – and may also affect our thinking and behavior.
Credit: Image: Vodovotz et al/Frontiers
From anxiety about the state of the world to ongoing waves of Covid-19, the stresses we face can seem relentless and even overwhelming. Worse, these stressors can cause chronic inflammation in our bodies. Chronic inflammation is linked to serious conditions such as cardiovascular disease and cancer – and may also affect our thinking and behavior.
A new hypothesis published in Frontiers in Science suggests the negative impacts may extend far further.
“We propose that stress, inflammation, and consequently impaired cognition in individuals can scale up to communities and populations,” explained lead author Prof Yoram Vodovotz of the University of Pittsburgh, USA.
“This could affect the decision-making and behavior of entire societies, impair our cognitive ability to address complex issues like climate change, social unrest, and infectious disease – and ultimately lead to a self-sustaining cycle of societal dysfunction and environmental degradation,” he added.
Bodily inflammation ‘mapped’ in the brain
One central premise to the hypothesis is an association between chronic inflammation and cognitive dysfunction.
“The cause of this well-known phenomenon is not currently known,” said Vodovotz. “We propose a mechanism, which we call the ‘central inflammation map’.”
The authors’ novel idea is that the brain creates its own copy of bodily inflammation. Normally, this inflammation map allows the brain to manage the inflammatory response and promote healing.
When inflammation is high or chronic, however, the response goes awry and can damage healthy tissues and organs. The authors suggest the inflammation map could similarly harm the brain and impair cognition, emotion, and behavior.
Accelerated spread of stress and inflammation online
A second premise is the spread of chronic inflammation from individuals to populations.
“While inflammation is not contagious per se, it could still spread via the transmission of stress among people,” explained Vodovotz.
The authors further suggest that stress is being transmitted faster than ever before, through social media and other digital communications.
“People are constantly bombarded with high levels of distressing information, be it the news, negative online comments, or a feeling of inadequacy when viewing social media feeds,” said Vodovotz. “We hypothesize that this new dimension of human experience, from which it is difficult to escape, is driving stress, chronic inflammation, and cognitive impairment across global societies.”
Inflammation as a driver of social and planetary disruption
These ideas shift our view of inflammation as a biological process restricted to an individual. Instead, the authors see it as a multiscale process linking molecular, cellular, and physiological interactions in each of us to altered decision-making and behavior in populations – and ultimately to large-scale societal and environmental impacts.
“Stress-impaired judgment could explain the chaotic and counter-intuitive responses of large parts of the global population to stressful events such as climate change and the Covid-19 pandemic,” explained Vodovotz.
“An inability to address these and other stressors may propagate a self-fulfilling sense of pervasive danger, causing further stress, inflammation, and impaired cognition in a runaway, positive feedback loop,” he added.
The fact that current levels of global stress have not led to widespread societal disorder could indicate an equally strong stabilizing effect from “controllers” such as trust in laws, science, and multinational organizations like the United Nations.
“However, societal norms and institutions are increasingly being questioned, at times rightly so as relics of a foregone era,” said Prof Paul Verschure of Radboud University, the Netherlands, and a co-author of the article. “The challenge today is how we can ward off a new adversarial era of instability due to global stress caused by a multi-scale combination of geopolitical fragmentation, conflicts, and ecological collapse amplified by existential angst, cognitive overload, and runaway disinformation.”
Reducing social media exposure as part of the solution
The authors developed a mathematical model to test their ideas and explore ways to reduce stress and build resilience.
“Preliminary results highlight the need for interventions at multiple levels and scales,” commented co-author Prof Julia Arciero of Indiana University, USA.
“While anti-inflammatory drugs are sometimes used to treat medical conditions associated with inflammation, we do not believe these are the whole answer for individuals,” said Dr David Katz, co-author and a specialist in preventive and lifestyle medicine based in the US. “Lifestyle changes such as healthy nutrition, exercise, and reducing exposure to stressful online content could also be important.”
“The dawning new era of precision and personalized therapeutics could also offer enormous potential,” he added.
At the societal level, the authors suggest creating calm public spaces and providing education on the norms and institutions that keep our societies stable and functioning.
“While our ‘inflammation map’ hypothesis and corresponding mathematical model are a start, a coordinated and interdisciplinary research effort is needed to define interventions that would improve the lives of individuals and the resilience of communities to stress. We hope our article stimulates scientists around the world to take up this challenge,” Vodovotz concluded.
The article is part of the Frontiers in Science multimedia article hub ‘A multiscale map of inflammatory stress’. The hub features a video, an explainer, a version of the article written for kids, and an editorial, viewpoints, and policy outlook from other eminent experts: Prof David Almeida (Penn State University, USA), Prof Pietro Ghezzi (University of Urbino Carlo Bo, Italy), and Dr Ioannis P Androulakis (Rutgers, The State University of New Jersey, USA).
Journal
Frontiers in Science
DOI
10.3389/1239462
Method of Research
Computational simulation/modeling
Subject of Research
Not applicable
Article Title
A multiscale inflammatory map: linking individual stress to societal dysfunction
Article Publication Date
12-Mar-2024
COI Statement
YV is a cofounder of, and stakeholder in, Immunetrics, Inc. and a consultant to Anuna AI. PFMJV is the founder of, and stakeholder in, Eodyne Systems s.l. and Sapiens5 Holding BV. DLK was employed by Tangelo – Intend, Inc. Neither these companies nor the funders mentioned above were involved in the study design, data collection, analysis, interpretation of data, the writing of this article, or the decision to submit it for publication. The companies mentioned above also did not provide funding for the study. The remaining author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors YV and PV declared that they are editorial board members of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
Acadia’s Nuplazid fails PhIII study due to higher-than-expected placebo effect
After years of trying to expand the market territory for Nuplazid, Acadia Pharmaceuticals might have hit a dead end, with a Phase III fail in schizophrenia…
After years of trying to expand the market territory for Nuplazid, Acadia Pharmaceuticals might have hit a dead end, with a Phase III fail in schizophrenia due to the placebo arm performing better than expected.
Steve Davis
“We will continue to analyze these data with our scientific advisors, but we do not intend to conduct any further clinical trials with pimavanserin,” CEO Steve Davis said in a Monday press release. Acadia’s stock $ACAD dropped by 17.41% before the market opened Tuesday.
Pimavanserin, a serotonin inverse agonist and also a 5-HT2A receptor antagonist, is already in the market with the brand name Nuplazid for Parkinson’s disease psychosis. Efforts to expand into other indications such as Alzheimer’s-related psychosis and major depression have been unsuccessful, and previous trials in schizophrenia have yielded mixed data at best. Its February presentation does not list other pimavanserin studies in progress.
The Phase III ADVANCE-2 trial investigated 34 mg pimavanserin versus placebo in 454 patients who have negative symptoms of schizophrenia. The study used the negative symptom assessment-16 (NSA-16) total score as a primary endpoint and followed participants up to week 26. Study participants have control of positive symptoms due to antipsychotic therapies.
The company said that the change from baseline in this measure for the treatment arm was similar between the Phase II ADVANCE-1 study and ADVANCE-2 at -11.6 and -11.8, respectively. However, the placebo was higher in ADVANCE-2 at -11.1, when this was -8.5 in ADVANCE-1. The p-value in ADVANCE-2 was 0.4825.
In July last year, another Phase III schizophrenia trial — by Sumitomo and Otsuka — also reported negative results due to what the company noted as Covid-19 induced placebo effect.
According to Mizuho Securities analysts, ADVANCE-2 data were disappointing considering the company applied what it learned from ADVANCE-1, such as recruiting patients outside the US to alleviate a high placebo effect. The Phase III recruited participants in Argentina and Europe.
Analysts at Cowen added that the placebo effect has been a “notorious headwind” in US-based trials, which appears to “now extend” to ex-US studies. But they also noted ADVANCE-1 reported a “modest effect” from the drug anyway.
Nonetheless, pimavanserin’s safety profile in the late-stage study “was consistent with previous clinical trials,” with the drug having an adverse event rate of 30.4% versus 40.3% with placebo, the company said. Back in 2018, even with the FDA approval for Parkinson’s psychosis, there was an intense spotlight on Nuplazid’s safety profile.
Acadia previously aimed to get Nuplazid approved for Alzheimer’s-related psychosis but had many hurdles. The drug faced an adcomm in June 2022 that voted 9-3 noting that the drug is unlikely to be effective in this setting, culminating in a CRL a few months later.
As for the company’s next R&D milestones, Mizuho analysts said it won’t be anytime soon: There is the Phase III study for ACP-101 in Prader-Willi syndrome with data expected late next year and a Phase II trial for ACP-204 in Alzheimer’s disease psychosis with results anticipated in 2026.
Acadia collected $549.2 million in full-year 2023 revenues for Nuplazid, with $143.9 million in the fourth quarter.
"Beware the Ides of March,” Shakespeare quotes the soothsayer’s warning Julius Caesar about what turned out to be an impending assassination on March 15. The death of American liberty happened around the same time four years ago, when the orders went out from all levels of government to close all indoor and outdoor venues where people gather.
It was not quite a law and it was never voted on by anyone. Seemingly out of nowhere, people who the public had largely ignored, the public health bureaucrats, all united to tell the executives in charge – mayors, governors, and the president – that the only way to deal with a respiratory virus was to scrap freedom and the Bill of Rights.
And they did, not only in the US but all over the world.
The forced closures in the US began on March 6 when the mayor of Austin, Texas, announced the shutdown of the technology and arts festival South by Southwest. Hundreds of thousands of contracts, of attendees and vendors, were instantly scrapped. The mayor said he was acting on the advice of his health experts and they in turn pointed to the CDC, which in turn pointed to the World Health Organization, which in turn pointed to member states and so on.
There was no record of Covid in Austin, Texas, that day but they were sure they were doing their part to stop the spread. It was the first deployment of the “Zero Covid” strategy that became, for a time, official US policy, just as in China.
It was never clear precisely who to blame or who would take responsibility, legal or otherwise.
This Friday evening press conference in Austin was just the beginning. By the next Thursday evening, the lockdown mania reached a full crescendo. Donald Trump went on nationwide television to announce that everything was under control but that he was stopping all travel in and out of US borders, from Europe, the UK, Australia, and New Zealand. American citizens would need to return by Monday or be stuck.
Americans abroad panicked while spending on tickets home and crowded into international airports with waits up to 8 hours standing shoulder to shoulder. It was the first clear sign: there would be no consistency in the deployment of these edicts.
There is no historical record of any American president ever issuing global travel restrictions like this without a declaration of war. Until then, and since the age of travel began, every American had taken it for granted that he could buy a ticket and board a plane. That was no longer possible. Very quickly it became even difficult to travel state to state, as most states eventually implemented a two-week quarantine rule.
The next day, Friday March 13, Broadway closed and New York City began to empty out as any residents who could went to summer homes or out of state.
On that day, the Trump administration declared the national emergency by invoking the Stafford Act which triggers new powers and resources to the Federal Emergency Management Administration.
In addition, the Department of Health and Human Services issued a classified document, only to be released to the public months later. The document initiated the lockdowns. It still does not exist on any government website.
The White House Coronavirus Response Task Force, led by the Vice President, will coordinate a whole-of-government approach, including governors, state and local officials, and members of Congress, to develop the best options for the safety, well-being, and health of the American people. HHS is the LFA [Lead Federal Agency] for coordinating the federal response to COVID-19.
Closures were guaranteed:
Recommend significantly limiting public gatherings and cancellation of almost all sporting events, performances, and public and private meetings that cannot be convened by phone. Consider school closures. Issue widespread ‘stay at home’ directives for public and private organizations, with nearly 100% telework for some, although critical public services and infrastructure may need to retain skeleton crews. Law enforcement could shift to focus more on crime prevention, as routine monitoring of storefronts could be important.
In this vision of turnkey totalitarian control of society, the vaccine was pre-approved: “Partner with pharmaceutical industry to produce anti-virals and vaccine.”
The National Security Council was put in charge of policy making. The CDC was just the marketing operation. That’s why it felt like martial law. Without using those words, that’s what was being declared. It even urged information management, with censorship strongly implied.
The timing here is fascinating. This document came out on a Friday. But according to every autobiographical account – from Mike Pence and Scott Gottlieb to Deborah Birx and Jared Kushner – the gathered team did not meet with Trump himself until the weekend of the 14th and 15th, Saturday and Sunday.
According to their account, this was his first real encounter with the urge that he lock down the whole country. He reluctantly agreed to 15 days to flatten the curve. He announced this on Monday the 16th with the famous line: “All public and private venues where people gather should be closed.”
This makes no sense. The decision had already been made and all enabling documents were already in circulation.
There are only two possibilities.
One: the Department of Homeland Security issued this March 13 HHS document without Trump’s knowledge or authority. That seems unlikely.
Two: Kushner, Birx, Pence, and Gottlieb are lying. They decided on a story and they are sticking to it.
Trump himself has never explained the timeline or precisely when he decided to greenlight the lockdowns. To this day, he avoids the issue beyond his constant claim that he doesn’t get enough credit for his handling of the pandemic.
With Nixon, the famous question was always what did he know and when did he know it? When it comes to Trump and insofar as concerns Covid lockdowns – unlike the fake allegations of collusion with Russia – we have no investigations. To this day, no one in the corporate media seems even slightly interested in why, how, or when human rights got abolished by bureaucratic edict.
As part of the lockdowns, the Cybersecurity and Infrastructure Security Agency, which was and is part of the Department of Homeland Security, as set up in 2018, broke the entire American labor force into essential and nonessential.
They also set up and enforced censorship protocols, which is why it seemed like so few objected. In addition, CISA was tasked with overseeing mail-in ballots.
Only 8 days into the 15, Trump announced that he wanted to open the country by Easter, which was on April 12. His announcement on March 24 was treated as outrageous and irresponsible by the national press but keep in mind: Easter would already take us beyond the initial two-week lockdown. What seemed to be an opening was an extension of closing.
This announcement by Trump encouraged Birx and Fauci to ask for an additional 30 days of lockdown, which Trump granted. Even on April 23, Trump told Georgia and Florida, which had made noises about reopening, that “It’s too soon.” He publicly fought with the governor of Georgia, who was first to open his state.
Before the 15 days was over, Congress passed and the president signed the 880-page CARES Act, which authorized the distribution of $2 trillion to states, businesses, and individuals, thus guaranteeing that lockdowns would continue for the duration.
There was never a stated exit plan beyond Birx’s public statements that she wanted zero cases of Covid in the country. That was never going to happen. It is very likely that the virus had already been circulating in the US and Canada from October 2019. A famous seroprevalence study by Jay Bhattacharya came out in May 2020 discerning that infections and immunity were already widespread in the California county they examined.
What that implied was two crucial points: there was zero hope for the Zero Covid mission and this pandemic would end as they all did, through endemicity via exposure, not from a vaccine as such. That was certainly not the message that was being broadcast from Washington. The growing sense at the time was that we all had to sit tight and just wait for the inoculation on which pharmaceutical companies were working.
By summer 2020, you recall what happened. A restless generation of kids fed up with this stay-at-home nonsense seized on the opportunity to protest racial injustice in the killing of George Floyd. Public health officials approved of these gatherings – unlike protests against lockdowns – on grounds that racism was a virus even more serious than Covid. Some of these protests got out of hand and became violent and destructive.
Meanwhile, substance abuse rage – the liquor and weed stores never closed – and immune systems were being degraded by lack of normal exposure, exactly as the Bakersfield doctors had predicted. Millions of small businesses had closed. The learning losses from school closures were mounting, as it turned out that Zoom school was near worthless.
It was about this time that Trump seemed to figure out – thanks to the wise council of Dr. Scott Atlas – that he had been played and started urging states to reopen. But it was strange: he seemed to be less in the position of being a president in charge and more of a public pundit, Tweeting out his wishes until his account was banned. He was unable to put the worms back in the can that he had approved opening.
By that time, and by all accounts, Trump was convinced that the whole effort was a mistake, that he had been trolled into wrecking the country he promised to make great. It was too late. Mail-in ballots had been widely approved, the country was in shambles, the media and public health bureaucrats were ruling the airwaves, and his final months of the campaign failed even to come to grips with the reality on the ground.
At the time, many people had predicted that once Biden took office and the vaccine was released, Covid would be declared to have been beaten. But that didn’t happen and mainly for one reason: resistance to the vaccine was more intense than anyone had predicted. The Biden administration attempted to impose mandates on the entire US workforce. Thanks to a Supreme Court ruling, that effort was thwarted but not before HR departments around the country had already implemented them.
As the months rolled on – and four major cities closed all public accommodations to the unvaccinated, who were being demonized for prolonging the pandemic – it became clear that the vaccine could not and would not stop infection or transmission, which means that this shot could not be classified as a public health benefit. Even as a private benefit, the evidence was mixed. Any protection it provided was short-lived and reports of vaccine injury began to mount. Even now, we cannot gain full clarity on the scale of the problem because essential data and documentation remains classified.
After four years, we find ourselves in a strange position. We still do not know precisely what unfolded in mid-March 2020: who made what decisions, when, and why. There has been no serious attempt at any high level to provide a clear accounting much less assign blame.
Not even Tucker Carlson, who reportedly played a crucial role in getting Trump to panic over the virus, will tell us the source of his own information or what his source told him. There have been a series of valuable hearings in the House and Senate but they have received little to no press attention, and none have focus on the lockdown orders themselves.
The prevailing attitude in public life is just to forget the whole thing. And yet we live now in a country very different from the one we inhabited five years ago. Our media is captured. Social media is widely censored in violation of the First Amendment, a problem being taken up by the Supreme Court this month with no certainty of the outcome. The administrative state that seized control has not given up power. Crime has been normalized. Art and music institutions are on the rocks. Public trust in all official institutions is at rock bottom. We don’t even know if we can trust the elections anymore.
In the early days of lockdown, Henry Kissinger warned that if the mitigation plan does not go well, the world will find itself set “on fire.” He died in 2023. Meanwhile, the world is indeed on fire. The essential struggle in every country on earth today concerns the battle between the authority and power of permanent administration apparatus of the state – the very one that took total control in lockdowns – and the enlightenment ideal of a government that is responsible to the will of the people and the moral demand for freedom and rights.
How this struggle turns out is the essential story of our times.
CODA: I’m embedding a copy of PanCAP Adapted, as annotated by Debbie Lerman. You might need to download the whole thing to see the annotations. If you can help with research, please do.
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