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Novavax Vaccine Proved to be Greater than 90% Effective Against COVID-19 Variants in US Phase 3 Trial

Shares of Novavax (NVAX) gained 2.3% on Friday after the company announced that its experimental COVID-19 vaccine candidate, NVX-CoV2373, showed a strong immune response and protection against the Beta variant
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This article was originally published by TipRanks.

Shares of Novavax (NVAX) gained 2.3% on Friday after the company announced that its experimental COVID-19 vaccine candidate, NVX-CoV2373, showed a strong immune response and protection against the Beta variant originally identified in South Africa, as well as against the original version of the coronavirus and the Alpha variant first found in the UK. Novavax, Inc., a U.S.-based biotechnology company, develops vaccines to counter seriously infectious diseases.  (See NVAX stock analysis on TipRanks) Gregory M. Glenn, M.D., President of Research and Development at Novavax commented, “These data suggest that not only could one booster dose of this variant-directed vaccine potentially provide a robust, protective immune boost after vaccination against the original SARS-CoV-2 virus, but also the potential to provide broad protection against various virus strains if used as a primary vaccine regimen." He further added, "This broad immune coverage is vital to controlling the pandemic as variants of concern continue to emerge worldwide that could jeopardize the protection created through ongoing COVID-19 vaccination efforts." The company said that the vaccine is being tested in multiple trials, including two pivotal Phase 3 trials and two ongoing Phase 2 studies. Notably, Novavax revealed that testing of blood serum of thirty participants from the Phase 2 clinical trial who had received both doses of NVX-CoV2373 revealed strong antibody responses to the original version of the coronavirus, as well as against both the U.K. and South African variants. Furthermore, Novavax said that studies in mice and baboons revealed that a different vaccine targeting the South African Beta variant produced immune response and protection. The company expects to conduct further clinical testing of the Beta-focused vaccine in the fall of 2021. B.Riley Financial analyst Mayank Mamtani recently reiterated a Buy rating and the price target of $286 (36.4% potential upside) on the stock. Mamtani sees NVAX’s risk/reward favorable based on his views that there is a great possibility of vaccine efficacy and that the "differentiated" safety and tolerability profile of NVX-CoV2373 is not yet fully reflected in the current share price. Overall, the stock has a Moderate Buy consensus rating based on 4 Buys and 2 Holds. The NVAX average analyst price target of $238.60 implies 13.8% upside potential from current levels.
Related News: United Airlines Launches Corporate Venture Capital Fund; Shares Drop 1.7% Medtronic Receives FDA Approval for Neurostimulator; Shares Rise 1.4% Occidental Petroleum Divests Non-Strategic Permian Basin Acreage for $508 Million The post Novavax Achieves Positive Results for COVID-19 Vaccine Candidate NVX-Cov2373 During Trials appeared first on TipRanks Financial Blog.

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This Thanksgiving, Supplies Of Turkey, Eggs, & Butter Will Be Extremely Tight In The US

This Thanksgiving, Supplies Of Turkey, Eggs, & Butter Will Be Extremely Tight In The US

Authored by Michael Snyder via The Economic Collapse…

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This Thanksgiving, Supplies Of Turkey, Eggs, & Butter Will Be Extremely Tight In The US

Authored by Michael Snyder via The Economic Collapse blog,

If you love to cook, this upcoming Thanksgiving may be a real challenge for you.  Thanks to a resurgence of the bird flu, supplies of turkey are getting tighter and tighter.  Sadly, the same thing is true for eggs.  And as you will see below, reduced milk production is sending the price of butter into the stratosphere.  Thanks to soaring prices, a traditional Thanksgiving dinner will be out of reach for millions of American families this year, and that is extremely unfortunate.  Of course all of this is happening in the context of a horrific global food crisis that is getting worse with each passing day.  Yes, things are bad now, but they will be significantly worse this time next year.

The bird flu pandemic that has killed tens of millions of our chickens and turkeys was supposed to go away during the hot summer months, but that didn’t happen.  And now that the weather is starting to get colder again, there has been a resurgence of the bird flu and this is “devastating egg and turkey operations in the heartland of the country”

Turkeys are selling for record high prices ahead of the Thanksgiving holiday as a resurgence of bird flu wipes out supplies across the US.

Avian influenza is devastating egg and turkey operations in the heartland of the country. If just one bird gets it, the entire flock is culled in order to stop the spread. Millions of hens and turkeys have been killed in recent weeks. As a result, prices for turkey hens are nearly 30% higher than a year ago and 80% above pre-pandemic costs. Just as concerning are inventories of whole turkeys, which are the lowest going into the US winter holiday season since 2006. That means there will be little relief from inflation for Thanksgiving dinner.

In the months ahead, we could see tens of millions more chickens and turkeys get wiped out.

Egg prices have already tripled in 2022 and the price of turkey meat is up 60 percent.  Unfortunately, this is likely just the beginning

Turkey hens are $1.82 a pound this week, according to Urner Barry, compared to $1.42 last year and $1.01 before the pandemic. Meanwhile, wholesale egg prices are at $3.62 a dozen as of Wednesday, the highest ever, up from a previous record of $3.45 a dozen set earlier this year, said John Brunnquell, chief executive officer of Egg Innovations, one of the biggest US producers of free-range eggs. Consumers have seen prices for eggs at grocery stores triple this year, while turkey meat rose a record-setting 60%, according to a Cobank report.

Meanwhile, supplies of butter are steadily getting tighter as well

Lower milk production on U.S. dairy farms and labor shortages for processing plants have weighed on butter output for months, leaving the amount of butter in U.S. cold storage facilities at the end of July the lowest since 2017, according to the Agriculture Department.

Tight supplies have sent butter prices soaring at U.S. supermarkets, surpassing most other foods in the past year. U.S. grocery prices in August rose 13.5% during the past 12 months, the largest annual increase since 1979, according to the Labor Department. Butter outstripped those gains, rising 24.6% over the same period.

The trends that are driving up the price of butter aren’t going away any time soon, and so we are being warned to brace ourselves for “elevated” prices for the foreseeable future…

The forces at work in butter highlight the challenge of curtailing inflation. Economic pressures fueling high prices for livestock feed, labor shortages and other factors could persist, keeping prices for the kitchen staple elevated longer term.

To me, slathering a piece of warm bread with a huge chunk of butter is one of the best things about Thanksgiving.

And most of us will continue to buy butter no matter how high it goes.

But the truth is that rapidly rising food prices are forcing vast numbers of Americans to adjust their shopping habits.  Here is one example

For Carol Ehrman, cooking is a joyful experience.

“I love to cook, it’s my favorite thing to do,” she said. She especially likes to cook Indian and Thai food, but stocking the spices and ingredients she needs for those dishes is no longer feasible. “When every ingredient has gone up, that adds up on the total bill,” she said.

“What used to cost us $250 to $300 … is now $400.” Ehrman, 60, and her husband, 65, rely on his social security income, and the increase was stretching their budget. “We just couldn’t do that.”

The global food crisis is starting to hit home for many ordinary Americans, and we need to understand that this crisis is still only in the very early chapters.

David Beasley is the head of the UN World Food Program, and he is actually using the word “hell” to describe what is potentially coming in 2023

“It’s a perfect storm on top of a perfect storm,” Beasley said. “And with the fertilizer crisis we’re facing right now, with droughts, we’re facing a food pricing problem in 2022. This created havoc around the world.”

“If we don’t get on top of this quickly — and I don’t mean next year, I mean this year — you will have a food availability problem in 2023,” he said. “And that’s gonna be hell.”

The World Food Program keeps sounding the alarm, but very few of us in the western world seem to be taking those warnings very seriously.

People are literally dropping dead from starvation in some areas of the globe right now, and a new report that the WFP just released says that there are 19 “hotspots” where we could see a “huge loss of life” between October and January…

World Food Programme (WFP) and the Food and Agriculture Organization of the United Nations (FAO) are out with a new report outlining countries that “are either already starving or on the brink of disaster.”

WFP and FAO found 19 hunger hotspots worldwide, with most countries in Africa, the Middle East, and even some in Central America. They call for urgent humanitarian action between October 2022 and January 2023 to avoid “huge loss of life.”

Afghanistan, Ethiopia, South Sudan, Somalia, Nigeria, Yemen, and Haiti are labeled “hotspots of highest concern,” facing catastrophic hunger levels.

The sort of famines that we were warned about are already starting to happen right in front of our eyes, but most people simply will not care as long as they are not going hungry themselves.

What those people do not realize is that this global food crisis is going to continue to spread.

As supplies of food get tighter and tighter, prices will continue to soar and shortages will become more common.

We truly are in unprecedented territory, and the pain that is ahead will greatly shock all of the lemmings that just kept assuming that everything would work out just fine somehow.

*  *  *

It is finally here! Michael’s new book entitled “7 Year Apocalypse” is now available in paperback and for the Kindle on Amazon.

Tyler Durden Thu, 09/29/2022 - 21:40

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Computers calling time on isolation

Kyoto–Across the world, many people infected with Covid-19 have been made to completely isolate from others in order to avoid passing on the infection….

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Kyoto–Across the world, many people infected with Covid-19 have been made to completely isolate from others in order to avoid passing on the infection. Some countries still recommend minimum isolation periods for as long as 10 days from when patients start to develop Covid-19 symptoms.

Credit: LAIMAN

Kyoto–Across the world, many people infected with Covid-19 have been made to completely isolate from others in order to avoid passing on the infection. Some countries still recommend minimum isolation periods for as long as 10 days from when patients start to develop Covid-19 symptoms.

Professor Shingo Iwami, affiliated with Kyoto University’s Mathematical Biology Laboratory at the Institute Advanced Study of Human Biology (WPI-ASHBi) says, “Although a long time for isolation reduces the overall risk of patients passing on the infection, there will always be patients who recover early and have to accept several days of redundant isolation while no longer posing an infection risk. We would like to calculate a way to reduce this unnecessary disruption in people’s lives as well as the broader losses for the economy.”

Writing in the journal Nature Communications, an international team of scientists, led by Iwami, has reported a simulation of the potential risks and benefits of ending an individual’s isolation early using antigen tests instead of isolating patients for a fixed time. They call for more sensitive and regular antigen testing to help reduce isolation periods for patients recovering from Covid-19.

The team decided to base their model on antigen rather than PCR testing, trading sensitivity for short turn-around time, low cost, and practicality. Iwami explains that although antigen tests do have a risk of generating “false-negatives” and fail to detect individuals who could still be infectious, there are clear benefits to getting results within an hour rather than waiting a day.

Their model accounts for the sensitivity of antigen tests as well as factors like the amount of virus in a patient that makes them infectious. These are then balanced against the acceptable risk of missing unrecovered and potentially infectious patients, by letting them out of isolation early.

Using their model, the team compared different scenarios to identify the best strategy. For example, the model projects that letting a recovering patient leave isolation after 2 consecutive negative results on 2 days in a row would spend 3.9 days of redundant isolation after their recovery. But under these conditions 1 in 40 patients would continue to pose an infection risk.

More conservative approaches might increase the burden on patients by requiring more than 2 consecutive negative test results of antigen tests.

Iwami says, “The epidemic has still not completely subsided, and we are living with a lot of uncertainty with regard to new variants of the virus. Antigen tests could help, but there is also a real need for worldwide systematic guidelines that simultaneously reduce risks and burdens. We hope this simulator will help doctors and policy makers meet those demands.”

******************
About WPI-ASHBi https://ashbi.kyoto-u.ac.jp/
Institute for the Advanced Study of Human Biology (ASHBi) was launched in October 2018 with funding from the World Premier International Research Center Initiative (WPI) Program of the Ministry of Education, Culture, Sports, Science and Technology (MEXT). The Institute inaugurated with 18 principal investigators (PIs) to create and promote human biology to elucidate key principles of human traits, including disease states. The Institute will perform interdisciplinary research between biology and mathematics (machine learning and topological data analysis) and between biology and humanities/social sciences (bioethics and philosophy on life), respectively. The Institute implements three research development cores for cutting-edge single-cell genome information analysis, primate genome editing, and non-human primate phenotype analysis, respectively. The Institute establishes a link with international institutions such as the EMBL, University of Cambridge, and Karolinska Institutet, creating a stratified organization for research promotion and strengthening its international profile.


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DoorDash Just Introduced Something Delightfully Dangerous

Chase has got an idea that DoorDash devotees are really gonna love.

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Chase has got an idea that DoorDash devotees are really gonna love.

Between work, exercise, socialization, and rest, cooking for yourself every night can sometimes feel like a big ask. But for those who live in foodie towns and cities, delivery services are a great way to experience all the delicious features your city has to offer without leaving your home. What a time to be alive!

Services like Uber  (UBER) - Get Uber Technologies Inc. Report, GrubHub, and DoorDash  (DASH) - Get DoorDash Inc. Class A Report have sprung up over the last decade to get food, alcohol, and other goods from merchants to consumers via delivery driver. Of those companies, DoorDash in particular has been expanding its services as of late -- and now it's found another way to grow its items-on-demand empire.

In 2020, coronavirus forced people all over the world back into their homes for an unforeseeable period of time. Lockdown and quarantine orders made going out a rare occurrence -- and for many of us, delivery services went from luxury item to lifeline to the outside world.

DoorDash began in 2013 as the brainchild of three Stanford University students in Palo Alto, California. Six months later, the company incorporated, and in late 2020, the company went public. On the first day of trading, their stock price jumped up by an impressive 86%.

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What's New From DoorDash?

This week, DoorDash is teaming up with Chase Bank  (JPM) - Get JP Morgan Chase & Co. Report to premiere the first ever DoorDash credit card. Card payments will process through Mastercard  (MA) - Get Mastercard Incorporated Report. Members will be able to use their card to access benefits and earn rewards both in and outside of the DoorDash app. Card users will get also have use of a complimentary 24/7 concierge service and access to Mastercard Priceless® Experiences.

“Connecting people with the best of their neighborhoods is core to our mission, and we’re excited to unlock even more of that value for customers with this first-of-its-kind credit card,” said DoorDash’s Senior Director of Global Partnerships Usman Cheema. “We are thrilled to deepen our relationship with Chase and continue building more everyday shoppable moments for consumers on and off the platform while empowering the local communities we serve.”

Ed Olebe, President of Chase Co-Brand Cards, added that “the new card is designed for those who love the convenience and options DoorDash provides and want to earn more where they are spending, whether ordering from the broad range of categories available on DoorDash or spending in-person at a favorite neighborhood store.”

Going Beyond Food Delivery

This isn't the first time DoorDash has teamed up with Chase. In 2020, the two began working together to bring customers extra food delivery perks. The bank began offering free DashPass memberships as a perk for cardholders.

DoorDash has been looking to offer more selection in the future, expanding its services to include grocery and alcohol delivery, too. The company has even reportedly tested a package pickup and delivery service in the past, though there no news if the service will be offered in the future. 

The company has been expanding its delivery partnerships to markets outside of restaurant service, too. It recently added Sprouts Farmers Market  (SFM) - Get Sprouts Farmers Market Inc. Report to its network, along with several other regional grocery chains across the United States. It also delivers goods from retail stores like Big Lots  (BIG) - Get Big Lots Inc. Report and Dick's Sporting Goods  (DKS) - Get Dick's Sporting Goods Inc Report.

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