Globalist Klaus Schwab made it clear that transhumanism is an integral part of “The Great Reset” when he said that the fourth industrial revolution would “lead to a fusion of our physical, digital and biological identity,” which in his book he clarifies is implantable microchips that can read your thoughts.
As we highlighted earlier, “The Great Reset” is attracting a deluge of fresh attention in the aftermath of the coronavirus pandemic, which Canadian Prime Minister Justin Trudeau said was an “opportunity for a reset.”
The agenda is primarily based around dismantling the current capitalist system in favor of greater centralized technocrat rule which will lead to lower living standards, less fuel consumption, fewer civil liberties and the accelerated automation of jobs.
However, another key aspect to “The Great Reset,” or the “fourth industrial revolution” as Schwab calls it, is merging man with machine.
“What the fourth industrial revolution will lead to is a fusion of our physical, digital and biological identity,” Schwab told the Chicago Council on Global Affairs.
Schwab went on to explain how his book, ‘Shaping the Future of The Fourth Industrial Revolution’, was particularly popular in China, South Korea and Japan, with the South Korean military alone purchasing 16,000 copies.
In the book, Schwab explains with excitement how upcoming technology will allow authorities to “intrude into the hitherto private space of our minds, reading our thoughts and influencing our behavior.”
He goes on to predict that this will provide an incentive for law enforcement to implement Minority Report-style pre-crime programs.
“As capabilities in this area improve, the temptation for law enforcement agencies and courts to use techniques to determine the likelihood of criminal activity, assess guilt or even possibly retrieve memories directly from people’s brains will increase,” writes Schwab. “Even crossing a national border might one day involve a detailed brain scan to assess an individual’s security risk.”
Schwab also waxes lyrical about the transhumanist utopian dream shared by all elitists which will ultimately lead to the creation of human cyborgs.
“Fourth Industrial Revolution technologies will not stop at becoming part of the physical world around us—they will become part of us,” writes Schwab.
“Indeed, some of us already feel that our smartphones have become an extension of ourselves. Today’s external devices—from wearable computers to virtual reality headsets—will almost certainly become implantable in our bodies and brains.”
Schwab also openly endorses something the media still claims is solely a domain of discussion for conspiracy theorists, namely “active implantable microchips that break the skin barrier of our bodies.”
The globalist hails the arrival of “implanted devices (that) will likely also help to communicate thoughts normally expressed verbally through a ‘built-in’ smartphone, and potentially unexpressed thoughts or moods by reading brain waves and other signals.”
So in other words, the “fusion of our physical, digital and biological identity” relates to the transhumanist singularity and a future where people have their every movement tracked and every thought read by an implantable microchip.
It isn’t a “conspiracy theory” when they’re openly telling you what they want to do.
* * *
2 High Yielding Canadian Dividend Stocks to Add Today
Many investors are looking to achieve financial freedom. Ditching that 9-5 job and being financially free is certainly a lifestyle to get excited about. To achieve this, many buy high-yielding Canadian dividend stocks. But, what many don’t realize is…
Many investors are looking to achieve financial freedom. Ditching that 9-5 job and being financially free is certainly a lifestyle to get excited about.
To achieve this, many buy high-yielding Canadian dividend stocks. But, what many don't realize is that the dividend yield of a company is not the first thing you should be looking at. In fact, a high yield can sometimes be a looming disaster. Look no further than the record-breaking amount of dividend cuts we had during the COVID-19 pandemic.
There's no point in purchasing a high yielding Canadian dividend stock if you're going to watch your capital shrink. So, in this article we're going to highlight a few options that not only present a high dividend yield for investors buying stocks to churn out more passive income, but a reliable dividend yield, one that can stand the test of time.
Reliability found in Enbridge (TSX:ENB)
If you're an income investor, you've likely heard of Enbridge (TSE:ENB). The company has paid a notoriously high yield for decades, and has maintained one of the longest dividend growth streaks in the country, raising consistently for more than 2 and a half decades.
Enbridge is a midstream company with a growing renewable energy portfolio. To give an indication of the company's dominance, it states that it is responsible for shipping more than 20% of the natural gas that is consumed in the United States, and 25% of North America's crude oil.
Enbridge (TSX:ENB) and the renewable future
Its renewable energy portfolio is quite small, accounting for only 3% of 2020 adjusted EBITDA, but it is one that is growing fast, and investors should take note. As we move further into the future, renewables will no doubt play a key role in Enbridge's growth.
There's also a chance you've glanced at Enbridge during a pre-screen and avoided the company due to excessively high payout ratios. Which, is fairly reasonable. The company is currently paying out over 110% of trailing earnings towards its dividend. But, you may be missing a massive opportunity here.
When analyzing pipelines, you want to be looking at something called distributable cash flow, or DCF. This cash flow calculation is produced by the company themselves, and calculations can vary to some degree. Given the complex business structure of a pipeline company, this is the most reliable indicator to use when it comes to dividend safety.
In 2021, Enbridge expects to generate $4.70-5 in distributable cash flow. With a dividend of $3.34 per year, this puts the company's payout ratio at 66.8% on the high end. Of note, Enbridge's target is to keep its payout ratio within this range, and the company has done so for quite some time.
Consistent cash flows in "take or pay" contracts
How has it managed to do so? Cash flow with pipelines is extremely consistent, due to long term take or pay contracts. Regardless of whether or not Enbridge is shipping product, the pipeline space is paid for. And not only this, Enbridge can turn around and charge someone else to utilize that space, even if it has already been paid for and goes unused.
This creates an extremely reliable cash flow stream despite the price of natural gas or oil, and is one of the major reasons why Enbridge and other midstream companies are not as susceptible to volatility in commodity prices.
Yielding 6.47%, Enbridge is a solid option to help you bolster your passive income stream and start generating long-standing wealth.
Beefy distribution in A&W Revenue Royalties Income Fund (TSX:AW.UN)
Royalty funds are often avoided due to their complex and confusing structure. However, many of them provide excellent opportunities for investors looking to generate passive income. A&W Revenue Royalties Income Fund (TSE:AW.UN) is one that does just that.
Many bears will point out that A&W in the United States has been struggling. However, in Canada it is a much different story.
A&W thriving in Canadian space
The company has over 1,000 restaurants in Canada and had system sales of over $1.4B in 2020, despite being in a global pandemic. The company has proven to be exceptionally skilled at marketing its products and has some of the best industry leading growth out of all fast food chains in Canada.
As a royalty company, A&W Royalty collects "top line" cash flows. Which means it is solely dependent on the sales driven through A&W restaurants. This means that its distribution can vary depending on how well the restaurants do, but overall it has been extremely reliable when it comes to payments.
Yes, the chain did suspend its $0.10 monthly distribution because of the pandemic in 2020, however it quickly made up for this by providing 2 special distributions of $0.30 and $0.20 when operations started back up later in the year.
Sales growth through the first 6 months of 2021
Prior to the pandemic, the company had achieved mid to high single digit same store sales growth over the last half decade, and it's off to a roaring start in 2021 as well, with 12.2% sales growth through the first 6 months. Through the first 6 months of the year the company has also added 34 new restaurants. To put this into perspective, the company added 37 in all of Fiscal 2020.
The fund yields 4.77%, and pays out on a monthly basis. Payout ratios will look high, but if you understand the operations of a royalty company, you'll know that it aims to pay out the vast majority of its distributable cash back to shareholders.
Overall, it seems consumers are willing to eat at A&W despite higher costs, which bodes well for the company's growth. It does this with great marketing and higher quality food than similar chains like Burger King and Mcdonalds, and investors are likely to enjoy a beefy (no pun intended) distribution for quite some time.
How Robots and A.I. are About To Change This $11 Trillion Industry Forever
TikTok’s nearly 700 million users seek medical advice from random individuals and charlatans, since anyone can claim to be a medical expert on this raging social media machine.
Dr. Google is also working overtime, receiving more than one billion…
TikTok’s nearly 700 million users seek medical advice from random individuals and charlatans, since anyone can claim to be a medical expert on this raging social media machine.
Dr. Google is also working overtime, receiving more than one billion healthcare questions every day.
Web MD is recording over one billion searches a year, too.
When you combine this voracious hunger for digital diagnosis, symptom checkers and immediate medical assistance, with a global mobile app market whose revenues had already hit $365 billion in 2018, and are now on track to generate over $935 billion by 2023 ...
You get one of the best bets on disrupting the virtual medicine industry to date. You get Big Tech built by doctors for doctors in the Global Library of Medicine (GLM).
You get Cara, the new, sophisticated AI, powered by the unique Global Library of Medicine, that has been trained by hundreds of doctors to think just like them.
Cara will be launching at the end of November, marking the first time in our medical history that we can check our symptoms online, at the touch of a button, and truly trust what we are being told.
Over the past five years, Treatment.com (CSE: TRUE; OTC: TREIF) has been developing the world’s next-generation AI symptom checker, picking up where the billions of requests were left hanging by Google and WebMD … and certainly by TikTok.
Now, the app is about to launch as Treatment Mobile with an intelligent digital assistant, Cara, with over 400 diagnoses by a global team of hundreds of doctors who are adding more every day.
A Digital Fix for a Broken Healthcare System
An overwhelming majority of Americans find the healthcare system impossible to navigate.
Nearly three-quarters have no idea how they will afford their healthcare.
Those two facts have led to a shocking increase in at-home health solutions.
Need a healthcare big tech vendor who knows North American Healthcare
From 2019 to 2020--even before the COVID-19 outbreak--telemedicine grew by 46%.
In 2020 alone, wellness apps were downloaded 1.2 billion times.
Major investment into the telemedicine space combined with a massive increase in uptake and rapidly rising favor among consumers has seen telehealth increase 38X so far in 2021 from pre-COVID levels.
In April 2020, right at the start of the pandemic, telehealth use was 78X higher than in February 2020, according to McKinsey.
Total VC investment into the digital health space in H1 2021 was $14.7 billion. That’s more than VC investment for all of 2020, and twice the amount for 2019. That leads McKinsey to project that 2021 could see total investment in the sector hit $30 billion.
The bottom line is this: American healthcare is broken, and digital offerings are a major element of the fix. Cara steps in at exactly the right time to provide the first sophisticated AI that can help bring it all together. This is where big money is going in the healthcare sector.
The Digital Doctor Is In
Working with the University of Minnesota Medical School, Treatment.com (CSE: TRUE; OTC: TREIF) has gathered the best doctors and tech engineers that built the Global Library of Medicine (GLM) from around the world to teach Cara to do two things that no other digital health platform has been able to do successfully:
1) Think like a real doctor
2) Provide consumers with a personalized health assessment and full-on health management
Cara integrates everything by providing consumers with a bridge to wellness, telemedicine, pharma and health products ...
Cara asks you questions about your symptoms and then sorts through millions of pieces of information that include historical medical cases, demographic data and advances in medical knowledge. The end result is a more accurate recommendation than any other digital tool in the world.
Cara helps you understand what your symptom could be. It helps you monitor and track health changes and understand your general health and prevent illness. It gives you personalized support and follow-up and even allows you to track and manage your entire family.
And it can all be integrated with Apple Health Kit, Apple Watch and FitBit.
Treatment’s AI has been so effective, in fact, that the University of Minnesota Medical School licensed it to test medical students.
How Does Cara Make Money?
The initial app will be free, but there is an impressive scalability here.
This is how the wildly lucrative world of apps works. Once the upfront costs of development and AI learning are paid for, it’s all revenue, all the time. And app revenue streams are recurring, which is exactly why the mobile app industry continues to surge.
Consumers will pay for recommendations through premium app subscriptions, and Treatment.com’s next move with Cara will be to add a series of paid plugins for everything from dermatology specialty segments, to cardiology.
Additionally, Treatment.com will seek health and wellness partners to integrate to access qualified referrals and improve efficiencies, while simultaneously reducing costs.
There are three revenue-generating avenues here: corporate licenses, health and wellness products and university medical school training.
But the biggest value here is that Cara is a goldmine of data …
Cara’s access to individualized health trends will help insurance providers and governments to provide better health services.
In healthcare, big data like this helps avoid preventable diseases by detecting them in their early stages.
The market for big data analytics in healthcare could be worth an astounding $68 billion by 2025, and Treatment.com will have a major advantage with Cara.
WebMD--a private company--is valued at $2.8 billion, and it doesn’t even have any AI to back it up.
Treatment.com, (CSE: TRUE; OTC: TREIF) which listed on the Canadian Securities Exchange on April 19th, 2021, is about to launch a healthcare app that could completely change the way we view and access healthcare.
Global Medical and AI Expertise
Founded by John Fraser and Dr. Kevin Peterson, Treatment.com International Inc. (CSE: TRUE)(OTC:TREIF) is a sophisticated big-tech setup from the roots up.
Fraser is a computer scientist and entrepreneur with a background in healthcare technology. He’s a 20-year IT software veteran who has done this before. He sold his first unicorn--Vision Share (now Abilities Network)--for over $1 billion.
Dr. Peterson is a leading doctor and tenured professor at the University of Minnesota Medical School. He was also the architect of an international disease surveillance and research system, the first such in the world.
Add to this a global team of doctors in the United States, Canada, Singapore, India, Ethiopia and South Africa and you have the makings of the most intelligent AI symptom checker and health care management platform on the planet.
Again, that’s why it’s been licensed to train medical students at the University of Minnesota.
The Next Healthcare Wave
The healthcare industry is overripe for disruption, and it’s being disrupted in waves.
The most recent wave saw Babylon Health, valued at $4.2 billion in its latest funding round, explode on the scene with an AI-powered platform for virtual clinical operations. Babylon is about to go public via a SPAC deal through a $4.2-billion merger with Alkuri Global Acquisition Corp., led by former Groupon executives.
It’s also been disrupted by Teladoc Health, the $25-billion telemedicine behemoth that has nicely rewarded investors. Investors who jumped in on this in early 2018 could have seen gains of over 1,500% by January this year.
When we miss one wave, we move on to the next because the healthcare industry is set to see wave after wave of disruption, and Cara comes next.
Set to launch by the end of October, Cara is about to go mainstream, and because of the global experts behind it, it stands a good chance of becoming the next app to go from zero to hero--and perhaps to billions.
Treatment.com International Inc. (CSE: TRUE; OTC: TREIF) has:
1) unfettered access to a data goldmine
2) A Global Library of Medicine (GLM) that is continually updated and referenced by its AI engine that will eventually scale up to all ~10,000 diseases known to man
3) Proprietary IP that could one day be worth billions of dollars
4) Massive growth runways
The next healthcare disruption is about empowering consumers to take better care--and control--of their health, and early-in investors may have a unique opportunity here with a new app that puts another big patch on a broken healthcare system.
Other companies looking to transform healthcare:
3D Signatures Inc. is a high-tech Canadian firm that has found itself in the center of two explosive sectors. It’s armed with an innovative new software platform which uses 3D analysis to target various diseases and help clinicians identify a diagnosis and optimize treatment plans. 3D Signatures’ software is saving doctors time which could be the difference of life and death for some patients. 3D Signatures sets itself apart from its competition through creating individualized treatment plans for patients. Using its mapping platform, the software can determine how a disease will progress and whether or not the patient will respond to treatment
3D Signatures’ broad scope and futuristic technology brings a promising opportunity to potential investors. It truly is at the forefront of a new era in medicine, and investors should not overlook this company’s massive potential.
CRH Medical Corporation specializes in products and services designed for the treatment of gastrointestinal diseases in the United States, Canada, and internationally. With a long history within the space, CRH has positioned itself as a leader in the field, trusted by medical professionals all over the world.
CRH also made a majpr acquisition at the beginning of the year, buying out Anesthesia Care Associates, LLC, an Indiana-based gastroenterology anesthesia practice. The estimated $2.6 million deal will increase CRH’s footprint in the space, and has been well received by investors.
AEterna Zentaris Inc. (TSX:AEZS) is a major biopharmaceutical up and comer. The company has seen steady growth, and an array of new developments over the recent years. With a focus on oncology, endocrinology, and women's health solutions, AEterna has created a variety of new products, including Macrilen, the first and only FDA-approved oral test for the diagnosis of Adult Growth Hormone Deficiency.
Recently, AEterna received European approval to market Macrillen which has pushed its value even higher. Dr. Christian Strasburger, the Head of Clinical Endocrinology at Charité Unversitaetsmedizin Berlin and the principal investigator for macimorelin explained, “Clinical studies have demonstrated that macimorelin is safer and much simpler to administer than the current methods of testing for insulin-induced hypoglycemia, and is well-tolerated by patients and reliable in diagnosing the condition.”
Aptose Biosciences Inc. (TSX:APS) is a biotech company specializing in personalized therapies to address Canada’s unmet oncology needs. The company uses genetic and epigenetic profiles to gain insights into certain cancers and patient populations in order to develop new treatments within the space.
Aptose has an exclusive partnership with Ohm Oncology to develop, manufacture and commercialize APL-581 in order to treat hematologic malignancies and related molecules.
Toronto-based Field Trip Health (TSX:FTRP) is taking a three-pronged approach in their work in the transformative psychedelic medicine sector. Not only are they involved in drug development, but they’re also involved in manufacturing and run a number of treatment clinics.
Field Trip has hit the ground running. With clinics currently operating in Toronto, Los Angeles, and New York, they have plans to ramp up to 75 clinics – providing psychotherapy along with psychedelic treatments. As one of the frontrunners in this exciting new industry, investors are keeping a close eye on Field Trip.
By. Charles Kennedy
** IMPORTANT NOTICE AND DISCLAIMER -- PLEASE READ CAREFULLY! **
PAID ADVERTISEMENT. This article is a paid advertisement. Advanced Media Solutions Ltd. and its owners, managers, employees, and assigns (collectively “the Publisher”) is often paid by one or more of the profiled companies or a third party to disseminate these types of communications. In this case, the Publisher has been compensated by Treatment.com International, Inc. Inc. (“Treatment.com” or “Company”) to conduct investor awareness advertising and marketing. Treatment.com paid the Publisher to produce and disseminate six articles profiling the Company at a rate of seventy-five thousand US dollars per article. This compensation should be viewed as a major conflict with our ability to be unbiased.
Readers should beware that third parties, profiled companies, and/or their affiliates may liquidate shares of the profiled companies at any time, including at or near the time you receive this communication, which has the potential to hurt share prices. Frequently companies profiled in our articles experience a large increase in volume and share price during the course of investor awareness marketing, which often ends as soon as the investor awareness marketing ceases. The investor awareness marketing may be as brief as one day, after which a large decrease in volume and share price may likely occur.
This communication is not, and should not be construed to be, an offer to sell or a solicitation of an offer to buy any security. Neither this communication nor the Publisher purport to provide a complete analysis of any company or its financial position. The Publisher is not, and does not purport to be, a broker-dealer or registered investment adviser. This communication is not, and should not be construed to be, personalized investment advice directed to or appropriate for any particular investor. Any investment should be made only after consulting a professional investment advisor and only after reviewing the financial statements and other pertinent corporate information about the company. Further, readers are advised to read and carefully consider the Risk Factors identified and discussed in the advertised company’s SEC, SEDAR and/or other government filings. Investing in securities, particularly microcap securities, is speculative and carries a high degree of risk. Past performance does not guarantee future results. This communication is based on information generally available to the public and on interviews with company management, and does not (to the Publisher’s knowledge, as confirmed by Treatment.com) contain any material, non-public information. The information on which it is based is believed to be reliable. Nevertheless, the Publisher cannot guarantee the accuracy or completeness of the information.
SHARE OWNERSHIP. The Publisher owns shares and / or options of the featured company and therefore has an additional incentive to see the featured company’s stock perform well. The Publisher does not undertake any obligation to notify the market when it decides to buy or sell shares of the issuer in the market. The Publisher will be buying and selling shares of the featured company for its own profit. This is why we stress that you conduct extensive due diligence as well as seek the advice of your financial advisor or a registered broker-dealer before investing in any securities.
FORWARD LOOKING STATEMENTS. This publication contains forward-looking information which is subject to a variety of risks and uncertainties and other factors that could cause actual events or results to differ from those projected in the forward-looking statements. Forward looking statements in this publication include, but are not limited to, the size and anticipated growth of the market for the company’s products, the anticipated growth of the market for AI-assisted products generally, the anticipated growth of the market for app-based products generally, the anticipated launch date for the company’s products, the anticipated growth of the market for health care app-based products generally, the anticipated launch date for the company’s products, and the anticipated growth and expansion of the medical library to which the company’s products have access. Factors that could cause results to differ include, but are not limited to, the companies’ ability to fund its capital requirements in the near term and long term, the management team’s ability to effectively execute its strategy, the degree of success of the AI technology used in the company’s products, the company’s ability to effectively market the company’s products to customers within its three anticipated revenue streams, supply chain constraints, pricing pressures, etc. The forward-looking information contained herein is given as of the date hereof and we assume no responsibility to update or revise such information to reflect new events or circumstances, except as required by law.
INDEMNIFICATION/RELEASE OF LIABILITY. By reading this communication, you acknowledge that you have read and understand this disclaimer, and further that to the greatest extent permitted under law, you release the Publisher, its affiliates, assigns and successors from any and all liability, damages, and injury from this communication. You further warrant that you are solely responsible for any financial outcome that may come from your investment decisions.
INTELLECTUAL PROPERTY. oilprice.com is the Publisher’s trademark. All other trademarks used in this communication are the property of their respective trademark holders. The Publisher is not affiliated, connected, or associated with, and is not sponsored, approved, or originated by, the trademark holders unless otherwise stated. No claim is made by the Publisher to any rights in any third-party trademarks.tsx pandemic covid-19 otc treatment testing fda genetic singapore africa india canada european
Bridget Martell on taking Yale spinout ‘to adulthood’; Cullinan Oncology CEO announces resignation as Bristol Myers hematology exec is welcomed aboard
Bridget Martell’s first clinical trial was an unorthodox one.
Then a resident in internal medicine at Yale, she was given an award to explore a career in clinical research — which was how she wound up leading a Phase I study for a…
Bridget Martell’s first clinical trial was an unorthodox one.
Then a resident in internal medicine at Yale, she was given an award to explore a career in clinical research — which was how she wound up leading a Phase I study for a therapeutic cocaine vaccine designed to help overcome addiction. She ended up overseeing the trial from Patient 1 to Patient 110 and, in the end, the early trial was positive.
“And so that’s when I realized that I needed to go to industry,” she said, “and understand how do you do this from start to finish? How do you string those pearls?”
Thus began a winding, 20-year journey that took her through every step on the proverbial bench to bedside journey — culminating in the CEO office at New Haven-based Artizan Biosciences.
Utilizing a platform technology developed by its Yale founders, the biotech has been scanning bacterial strains to pick out bad bacteria and cooking up small molecules to target them for both gastrointestinal and CNS disorders, an approach it dubs “precision microbiome medicine.” Artizan is now “on track” to name its lead candidates.
“I liken it to, you know, Jimmy took it out of infancy,” Martell said, referring to former CEO Jimmy Rosen. Now that Artizan has grown into a toddler, “I have to take it to adulthood.”
As a first-time CEO, she expects to leverage every aspect of her wide-ranging background for the new challenge: the scientist who studied microbiology and immunology; the internist exposed to a whole array of diseases thrown at her; the clinical trial strategist with experience at Pfizer, Kura Oncology and boutique CRO RRD International; the biotech mentor and advisor she played while consulting for companies and serving as entrepreneur-in-residence at Yale’s Office of Cooperative Research.
She will have help from a small team of 13 — an “amazing team” whom she cites as a big factor for the decision to get into the trenches — as Artizan looks to establish itself in a burgeoning field that’s grappled with its share of failures.
“So we’re not manipulating the microbiome, in terms of removing or adding bugs or feeding bugs. What we’re doing is we’re actually affecting the factors that are perturbing the ultimate balance in the GI tract and the inflammation,” she said. “Unfortunately, some of the failures are what I just spoke about, and that is, it’s complex, right? But, you know, if you start to chip away at what some of those mechanisms are, hopefully we will start to have a broader understanding.”
— Amber Tong
→ Co-founded by Patrick Baeuerle — who was on our list of 20 influential R&D execs in late August — Cullinan Oncology ended up raising $287.4 million in an IPO that helped get the proverbial Nasdaq ball rolling in 2021. Now comes word that Owen Hughes has resigned as CEO and Cullinan has already lined up Bristol Myers Squibb’s Nadim Ahmed as his successor. Hughes, who slips into an advisory role during the transition, will no longer be on Cullinan’s board of directors.
Ahmed, who was with GlaxoSmithKline from 1992-2010, becomes a chief executive here after two years as EVP and president of hematology at Bristol Myers. After GSK, he moved to Celgene, starting out as senior director, global marketing in the multiple myeloma franchise and climbing up to president, global hematology & oncology before the buyout.
→ There’s some reshuffling taking place at Sio Gene Therapies, which was once Axovant until the company shed its vant-ness last November. On Nov. 12, chief R&D officer Gavin Corcoran is hitting the road for “an opportunity with a private healthcare technology company,” leaving president and CEO Pavan Cheruvu to handle Corcoran’s responsibilities henceforth. Along with this news, Sio — whose gangliosidosis program has shown promise in Phase I/II — is opening up searches for a CMO and SVP of early development and scientific affairs, both new positions.
→ The ubiquitous Mace Rothenberg has stacked up the appointments after his retirement from Pfizer, and the drug giant’s ex-CMO emerges once again as senior advisor to CEO Paul Peter Tak at Candel Therapeutics. In the last nine months, Rothenberg has collected board seats at Surrozen, Tango Therapeutics, and Aulos Bioscience, and he’s joined the mission advisory board at EQRx. “Candel is at the forefront of one of the most exciting approaches in cancer immunotherapy,” Rothenberg said in a statement. “I am excited by the opportunity to help Paul Peter advance the company’s promising oncology pipeline.”
→ CBO Michelle Chen is the latest exec to join Alex Zhavoronkov’s squad at Al drug discovery startup Insilico following the appointment of CFO Nirav Jhaveri last month. Chen carries a business development background from such big names as Roche, Merck and BioMarin; fast forward to the present, and Chen makes her exit from WuXi Biologics, where she was SVP of corporate development and discovery business development.
→ A year ago, Peer Review told you about Brittany Bradrick’s arrival at ViaCyte as CFO (later becoming COO as well), but Bradrick has left ViaCyte to accept the CFO job at OrbiMed-backed Neurelis, whose lead drug Valtoco (diazepam nasal spray) was approved by the FDA last year to treat seizures. Neurelis’ CFO since 2011, George Stuart, will now jump to the COO post at Neurelis subsidiary Aegis Therapeutics. Additionally, ex-Five Prime EVP and CFO David Smith has claimed a seat on Neurelis’ board of directors.
→ There’s a slate of promotions at Urovant after the FDA approval of Gemtesa in December 2020 and subsequent data in September that showed the overactive bladder drug didn’t have a statistically significant effect on blood pressure or heart rate. And CEO Jim Robinson is welcoming a new exec: Laura Genatossio (SVP and general manager, Europe) is the lone newbie who pivots to Urovant after being Sarepta’s VP and general manager in the Europe, Middle East and Africa (EMEA) region. As for the promotions, Alana Darden Powell gets elevated to VP, corporate communications after her year as executive director of business unit operations, communications, and alliance management; Mark Niemaszek joined Urovant last year as VP of commercial operations and jumps to SVP, corporate planning; and after three years as VP, associate general counsel and head of intellectual property, Allergan vet Ted Chan scores the SVP title.
→ Raleigh, NC-based gene therapy player Opus Genetics, the brainchild of Spark co-founder Jean Bennett that launched a month ago with a $19 million round, has picked up Ash Jayagopal as CSO and Joe Schachle as COO. Jayagopal concludes his two years as executive director of discovery medicine at Kodiak Sciences, and before that he was head of molecular pharmacology and biomarkers in ophthalmology at Roche, which bought Spark in 2019. Schachle makes the transition to Opus from his second stint at Grifols, where he was VP of global commercial services & controlling and later the VP of customer experience enablement.
→ Formerly the Massachusetts Center for Advanced Biological Innovation and Manufacturing (CABIM), Landmark Bio has installed Gregg Nyberg as chief technology officer and Michael Covington as chief quality and regulatory officer. Nyberg spent almost 15 years at Amgen, then moved on to Merck in 2017 and was the associate VP and head of biologics process development at Merck Research Laboratories. Covington, who was with Amgen from 1993-2003, has held consecutive posts at Novartis Gene Therapies and Orchard Therapeutics as VP of regulatory CMC.
→ To the mountains we go, where University of Colorado oncology spinout OnKure Therapeutics has named faculty member Jennifer Diamond as CMO. Diamond is an associate professor of medicine in the Division of Medical Oncology at CU’s Anschutz Medical Campus, the same institution where Rain Therapeutics’ Robert Doebele has also taught. Led by Array BioPharma co-founder Tony Piscopio, OnKure raised a Series B that totaled $55 million in March.
→ Staying in Boulder, Enveda Biosciences has poached August Allen from Recursion, recruiting him as chief platform officer. Allen, who began as a research associate at Recursion in 2016, rose to director of product management before Enveda came calling. Enveda, a biotech where machine learning and natural biology commingle and which teed up a $55 million Series A in June, is led by CEO Viswa Colluru, a Recursion alum in his own right.
→ Valerie Jansen has been promoted to CMO at Elevation Oncology, the Shawn Leland-helmed startup that introduced itself in July 2020 and then pulled in a $65 million Series B the following November. Jansen, who took over as VP of clinical development at Elevation back in April, previously served as executive medical director at Mersana Therapeutics and senior medical advisor at Eli Lilly.
→ General Atlantic had top billing on a meaty $143 million Series B round for CinCor Pharma last week. The Cincinnati biotech has now pegged Mason Freeman as EVP, clinical development, and leading the pipeline is the aldosterone synthase inhibitor CIN-107 from Roche. A longtime Massachusetts General Hospital vet who founded the facility’s Translational Research Center, Freeman is a venture partner at 5AM Ventures who has Big Pharma experience at Novartis as head of the translational medicine program for cardiovascular & metabolic diseases.
→ Things are percolating on the leadership front at Applied Genetic Technologies Corporation with the appointments of CMO Susan Schneider and VP of clinical operations Sarah DiSalvatore. Schneider, the former SVP of clinical development, ophthalmology at Eloxx Pharmaceuticals and then Ji Xing Pharmaceuticals, is a Genentech and GSK vet who’s been VP and therapeutic area head of glaucoma and retina with Allergan. After working in clinical operations at Helsinn and Stemline Therapeutics, DiSalvatore was recently associate VP of clinical operations for Rocket Pharmaceuticals. Her first day is Nov. 1, while Schneider starts on Nov. 8.
→ Placing an emphasis on treating disorders known as RASopathies which are fueled by the activation of the Ras/Raf/MEK/ERK pathway, Pennsylvania-based NFlection Therapeutics has tapped William Hodder as CEO and is bulking up its leadership team with COO Gerd Kochendoerfer, VP of clinical operations Patrice Horwath and SVP of global regulatory affairs & quality assurance Libbie Mansell. Hodder captures the top spot here after two years as CBO of Escient Pharmaceuticals and he’s also been a corporate development exec at FibroGen and Protagonist Therapeutics. Kochendoerfer, a FibroGen vet as well in drug development, was SVP and head of operations at BridgeBio’s PellePharm. A Medtronic alum, Horwath has been a clinical operations director at Ralexar Therapeutics, while Mansell just wrapped up a brief tenure as AskBio’s SVP, regulatory affairs.
→ Bethesda, MD-based Gain Therapeutics, which released positive results from its induced pluripotent stem cell (iPSC) study on Gaucher and Parkinson’s disease last month, has appointed Matthias Alder as COO. Before joining Gain, Alder was CBO at Autolus Therapeutics. He has also served as an EVP at Sucampo Pharmaceuticals and Kuros Biosciences (formerly Cytos Biotechnology).
→ Backed by the Boehringer Ingelheim Venture Fund and taking aim at ALS and frontotemporal dementia with its lead asset, San Diego neurodegenerative disease biotech Libra Therapeutics has brought in Philip Lambert as CSO. Before joining Libra, which made its debut last September with a $29 million Series A haul, Lambert was the chief scientist at Centogene and has also been head of discovery at Charles River Laboratories.
→ German-based Curexsys has plucked up Christian Eckert as COO. Eckert makes his way to the exosome-focused company from Bristol Myers, where he was responsible for GMP manufacturing, amongst other duties. Before that, Eckert was with Medigene and Evotec.
→ Lori Gavrin has been appointed to the newly created position of chief business and strategy officer at NeuExcell Therapeutics. Gavrin served most recently as VP of corporate development at Tmunity, and she’s also worked in leadership positions at Wyeth/Pfizer and GSK. Last month, Pennsylvania-based NeuExcell struck a manufacturing deal with Fujifilm centering on its gene therapy NXL-001 for ischemic cortical stroke.
→ Barcelona oncology startup ONA Therapeutics has reached into the GSK talent jar to pluck Haijun Sun as CSO. After three years at F-star — where he was VP of biological products — Sun spent a year with Tizona Therapeutics as VP of antibody development. He joined GSK in 2017 and was the pharma giant’s head of antibody pharmacology before landing his first C-suite job here at ONA, which launched last summer with Bpifrance and Spanish VC Ysios Capital contributing to the €30 million round. Ona has also given its scientific advisory board a boost by naming the following: Pamela Klein, Cédric Blanpain, Sean Morrison, Josep Tabernero, Mark Throsby and ONA scientific co-founder Salvador Aznar Benitah.
→ Katharina Staufer has signed on to be CMO at Swiss rare liver disease biotech Versantis. Staufer comes to Versantis from Inselspital — also known as the University Hospital of Bern — where she was head of transplant medicine. CEO Vince Forster discussed the “undelivery mechanism” in Versantis’ platform with Endpoints News when the company nabbed Series B funding in September 2019.
→ Troy Wilson’s Kura Oncology has paved the way for Teresa Bair to be chief legal officer. Bair spent six years at Athenex and since June 2020 she had taken on the roles of EVP, general counsel and SVP, administration. Kura’s menin inhibitor KO-539 is now in Phase Ib for patients with relapsed or refractory acute myeloid leukemia.
→ South San Francisco-based Novome Biotechnologies has recruited Bill McLeod as CFO. McLeod most recently served as a corporate finance consultant to Surrozen. Prior to that, McLeod spent a decade at Stifel, where he served as co-head of equity capital markets. McLeod’s other roles include stints at JP Morgan and Bank of America, among others.
→ Alopexx has reeled in Thomas Thomas as CFO. Thomas joins the Cambridge, MA-based company with experience from his roles at the Stupski Foundation (CEO from 2009-2010) and Genentech (corporate treasurer from 2001-2006). Additionally, Thomas serves as an independent director on the board of Opiant Pharmaceuticals.
→ Paris-based Pharnext has welcomed some fresh faces to its management team with the appointments of Raj Thota (chief manufacturing officer and head of CMC) and Abhijit Pangu (head of regulatory affairs). Additionally, the company has promoted Xavier Paoli to COO. Thota comes to Pharnext from Frontida BioPharm, where he served as VP, general manager. Meanwhile, Pangu joins with experience from his times at Orphazyme and Ferring among others. Last, but not least, Paoli joined Pharnext in 2014 as commercialization strategy director. Prior to this stint, Paoli was with GSK, UCB and Alexion.
→ IASO Biotherapeutics has brought on Alan Fu as CFO. Fu most recently served as managing director of Haitong International and director of Citigroup Global Markets. Earlier in his career, Fu served at Rigel Pharmaceuticals.
→ Boston-based X4 Pharmaceuticals has methodically assembled its leadership in the last year, whether it’s with newcomers (CSO Art Taveras and CMO Diego Cadavid) or promotions (COO Mary DiBiase). This time around, X4 has selected Karolyn Park from Takeda as VP, US commercial. Park was senior director, US hematology portfolio strategy In her latest role at Takeda, and she has experience with Aduhelm before its controversial approval as Biogen’s associate director, global aducanumab commercial. In other X4 developments, Shire rare disease vet Françoise de Craecker has joined the board of directors.
→ Seagen CEO Clay Siegall has been named chairman of the board at fellow Seattle biotech Umoja Biopharma. The oncology-focused Umoja is flush with cash after successive financing rounds of $53 million and $210 million in November 2020 and June, respectively.
→ Chaired by new Mirati CEO David Meek, the board of directors at uniQure now includes Rachelle Jacques. The company Jacques leads, Enzyvant, just received FDA approval last Monday with the one-time regenerative therapy Rethymic for babies with congenital athymia.
→ Plunging down the Covid-19 leaderboard after the rejected its lenzilumab EUA pitch, Humanigen is loading up on more board members. Former Novartis exec John Hohneker juggles other board seats at BioTheryX, Cygnal, Aravive, Evelo Biosciences and Trishula Therapeutics, and Fosun vet Kevin Xie has been Gracell’s CFO since July 2020.
→ Sarepta’s CMO and EVP of research and development Gilmore O’Neill is making his way onto the board of directors at Aptinyx. Prior to his current stint at Sarepta, O’Neill spent 15 years at Biogen, where he held roles in the development programs for Alzheimer’s disease, movement disorders, neurology, multiple sclerosis, pain, neuromuscular disease, gene and cell therapy, and rare diseases.
→ Duking it out in the liquid biopsy space with companies like Caris and Thrive Earlier Detection, Redwood City, CA-based Guardant Health has elected Myrtle Potter to the board of directors. An ex-COO at Genentech, Potter joined Roivant in 2018 and is currently CEO of Sumitovant Biopharma.
→ Zai Lab has made Scott Morrison a member of the board of directors just a couple weeks after looking to file a BLA submission for the MacroGenics antibody margetuximab in China. Morrison, who retired from Ernst & Young, is on the boards of Audentes, Corvus Pharmaceuticals, Global Blood Therapeutics, Ideaya Biosciences and Vera Therapeutics.
→ Paul Wotten-led Obsidian Therapeutics is leaning on someone familiar with the TIL arena by appointing Maria Fardis to the board of directors. Back in May, Fardis resigned as CEO of Iovance almost immediately after the company said they’d have to delay the BLA filing of their gene therapy by at least another year.
→ Looking to fight off cytotoxic T and NK cells, autoimmune disease and cancer biotech Abcuro has added Darlene Deptula-Hicks to the board of directors. Since 2019, Deptula-Hicks has been CFO at F-star and is the former CFO at Pieris.
→ CDMO Biovectra has added two new faces to its board of directors with the appointments of Gordon McCauley (president and CEO of adMare BioInnovations) and Steven Klosk (former CEO of Cambrex Corporation).
Derek Graf also contributed to this edition.nasdaq covid-19 vaccine fda genetic therapy africa europe china
Copper Price Update: Q3 2021 in Review
Jim Chanos: China’s “Leveraged Prosperity” Model Is Doomed…And That’s Not The Worst Of It
The FDA’s War Against The Truth On Ivermectin
Robotic Textiles for Breathing Recovery
Zinc Prices Hit 14 Year High as Power Costs Rise
What is COP26? Here’s how global climate negotiations work and what’s expected from the Glasgow summit
Seeking Solace in an Equal-Weight Cybersecurity ETF
Do You Know About This Secret Government ‘Financial Crisis’ Situation Room In the White House?
Report: China coerces McDonald’s to adopt e-CNY ahead of Winter Olympics
FDA okays Moderna, J&J COVID jab boosters, plus ‘mix and match’
Crypto14 hours ago
Walmart Rolls Out Bitcoin ATMs Across 200 Stores Nationwide
Stocks19 hours ago
Tesla share price forecast after Q3 results
Stocks9 hours ago
Zinc Prices Hit 14 Year High as Power Costs Rise
Stocks7 hours ago
PayPal Stock Forecast: Everything You Need to Know Before Investing
Stocks17 hours ago
Stocks That Miss Expectations Are Being Hammered By The Most On Record
Crypto15 hours ago
Shanghai Man: Blockchain Week with Vitalik still happening, ‘Bitcoin’ searches on WeChat hit 26M in a day
Science23 hours ago
JPM: “We Could Be Just Weeks Away From Cushing Effectively Running Out Of Crude”
Economics23 hours ago
MLB Trade Rumors and News: Braves and Astros both on the verge of World Series berths