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Pooling society’s collective intelligence helped fight COVID – it must help fight future crises too

The WHO is creating a Global Pandemic Radar – an example of collective intelligence that must learn lessons from this pandemic.

Wisiel/Shutterstock

A Global Pandemic Radar is to be created to detect new COVID variants and other emerging diseases. Led by the WHO, the project aims to build an international network of surveillance hubs, set up to share data that’ll help us monitor vaccine resistance, track diseases and identify new ones as they emerge.

This is undeniably a good thing. Perhaps more than any event in recent memory, the COVID pandemic has brought home the importance of pooling society’s collective intelligence and finding new ways to share that combined knowledge as quickly as possible.

At its simplest, collective intelligence is the enhanced capacity that’s created when diverse groups of people work together, often with the help of technology, to mobilise more information, ideas and knowledge to solve a problem. Digital technologies have transformed what can be achieved through collective intelligence in recent years – connecting more of us, augmenting human intelligence with machine intelligence, and helping us to generate new insights from novel sources of data.

So what have we learned over the last 18 months of collective intelligence pooling that can inform the Global Pandemic Radar? Building from the COVID crisis, what lessons will help us perfect disease surveillance and respond better to future crises?

People want to help scientists

Responding to new and emerging threats requires new methods for filling data and evidence gaps fast. Collective intelligence methods like citizen science have been widely used in the environmental sector for years, but savvy scientists quickly saw the opportunity to deploy these and other approaches to tap into the public’s appetite to contribute to the COVID-19 response.

Before doctors had access to mass community testing or accurate forecasting, for instance, data provided by the public was a valuable early source of information. For example, researchers at King’s College London quickly developed the COVID Zoe symptom tracker app, to which over 4.6 million people have contributed their symptoms since March 2020. This data played a critical role in helping us understand how the virus affects different groups of people, exposing the variety of COVID-19 symptoms people have experienced.

Even gamers have played their part behind the scenes. Project Discovery is described as a citizen science “mini-game”, in which gamers explore outer space while drawing polygons around clusters of cells. The cell populations they trace around are from flow cytometry data that would ordinarily be painstakingly pored over by scientists to see how a COVID infection affects different types of cell. Over 327,000 gamers have taken part since June 2020, saving scientists an estimated 330 years of research.

Perhaps more visibly, vaccine development efforts have also been fuelled by volunteers. Over 500,000 people signed up to the UK’s COVID vaccine studies volunteer service.

Scientific training and research funding is not usually geared towards public participation and collaboration. That means, despite the potential, the public is typically excluded from participation in scientific research. Changing this might help us shift the dial on preventing the next pandemic and tackling a whole host of our other complex challenges, such as climate change.

Making sense of too much data

Alongside this rise in citizen science, 2020 was also a bumper year for scientific research, seeing a 15% increase in paper submissions. Over 475,000 COVID-related papers and pre-prints have been shared online as of June 2021.

This feverish scientific reporting, especially intense in the field of health and medicine, has raised concerns about quality control. Traditional processes of peer review have come under strain, with papers increasingly released as pre-prints, before they’ve been peer reviewed. Meanwhile, decision-makers face the challenge of finding the most relevant resources in the face of information overload.


Read more: How The Conversation handles pre-prints


The collaborative health evidence database, Epistemonikos, offers some relief to these challenges. It uses a combination of machine learning algorithms and crowd validation to identify all of the clinical systematic reviews related to the search query entered by the user.

In the past, it was used by policymakers in Chile to accelerate the process of public health legislation. Since 2020, the team behind Epistemonikos has identified more than 6,000 systematic reviews related to COVID-19 within their database. Highlighting these has helped health professionals and decision-makers find what they’re looking for amid the noise.

It isn’t just scientific research that has proved difficult to make sense of. The flood of data about the pandemic has also required careful collation, seeing as it often comes from multiple sources and is scattered across different websites and open databases, many of which follow different standards and formats. Data about a crisis is only useful if it’s synthesised and presented in ways that decision makers can understand.

One retrospective study showed how Google searches involving pandemic-related keywords, like “pneumonia”, could have been used to spot the early warning signs of COVID-19 spreading in Europe. The same finding was reached using Twitter data, and could in the future be reached with data from wearable technology. For now, these novel sources of data aren’t integrated into wider surveillance efforts, but doing so could help governments get better at anticipating crises in the future.


Read more: Big data can help doctors predict which COVID patients will become seriously ill


In the US, the absence of a publicly available system for aggregating COVID-related data led to the creation of the COVID Tracking Project. A community of over 300 volunteers collected, curated and analysed data sources to produce the most comprehensive public source of information about COVID in the US. Their efforts helped process under-reported data on those in long-term care and the incidence of COVID organised by race and ethnicity.

However, another promising pandemic initiative, the Collective and Augmented Intelligence Against COVID-19 (CAIAC) project, failed to get off the ground, despite the support of UNESCO and the Stanford Institute for Human-Centered Artificial Intelligence. The lesson: productively combining human and machine intelligence could help us deal with overwhelming amounts of data, but it isn’t easy. Creating and maintaining new global data infrastructures takes time, effort and significant investment.

Diversity enhances collective intelligence

There’s more we can do to properly harness collective intelligence when facing future crises. More data certainly helps, and those who organise that data can help thrust it before key decision makers as quickly as possible. But who makes the decisions matters too.

With the world taken by surprise, it seems that COVID-19 decision making followed the usual modus operandi of excluding the voices of women and minorities. An analysis of 115 COVID-19 decision-making and expert task forces from 87 countries, including the UK and the US, found that just 3.5% had gender parity in their membership, while 85.2% were majority men. Would the disproportionate impact of COVID-19 on black and ethnic minority communities and women have been as severe if these expert groups had been more diverse?


Read more: '49% more likely to die' – racial inequalities of COVID-19 laid bare in study of East London hospitals


The collective intelligence literature has long pointed to the potential of diversity in problem solving, but these positive effects can only be realised if institutions actively seek out a variety of voices. Without finding better ways to bring diverse perspectives into decision making, we’re not going to get too excited about how equally the benefits of the Global Pandemic Radar, and other future efforts to pool data and intelligence, will be felt.

While COVID has elevated AI-enabled modelling to the heart of government decisions, there is still a long way to go before these models are accessible to ordinary people - something which could help diversify decision making. This is where more creative participatory methods, aimed at helping members of the public explore the consequences of policy decisions and collective behaviours, may have a part to play.

The Corona Minister game allows people to explore the consequences of different policy interventions as they navigate trade-offs between public health, the economy and civil rights. Elsewhere, researchers in Denmark have created a VR gaming experience where citizens navigate through crowded scenes and try to avoid infection. The aim of the experience is to help participants engage with the complexity of disease spread and the role played by vaccination.

Making progress in how we can effectively think, decide and act together is an area that receives almost no research investment. We think using AI to make the most of the distributed collective intelligence of large, diverse groups is a major frontier for innovation, and a huge opportunity to prepare the population for a future crisis.

Invest in bottom-up initiatives

From Ebola to COVID, we’ve learned time and again that crises require both top-down and bottom-up responses. So while the Global Pandemic Radar is a great step forward, governments who are serious about crisis prevention and response need to start supporting the digital and social infrastructures that enable communities to act intelligently themselves.

In 2020, we saw how existing systems of community action were able to pivot quickly to focus on COVID-19. One of them was MetaSUB, a global project to build microbial portraits of urban transit systems that’s been around since 2015. With a network of volunteers and scientists in over 100 cities, they take regular swabs from trains and escalators, testing the pathogens they find for any markers of antibiotic resistance.

The pandemic saw them quickly set up the MetaCOV project, applying their previous methodology to see how microbial samples changed during the pandemic. Their data helped show that the longer COVID-19 was on a surface, the less likely it was to make someone sick.

Then there’s the FluCast forecasting system, which has been tapping into the “wisdom of crowds” to predict seasonal flu trends for the US Centres for Disease Control since 2015. The system was swiftly repurposed into CovidCast in 2020, which relies on open data sources and the participation of volunteers. CovidCast now offers real-time data across a range of indicators – including mask wearing and COVID-related visits to doctors – to forecast regional spikes in COVID infections and hospitalisations.

That these systems were already present and connected meant they could rapidly be deployed to serve pressing new requirements. Many community-led responses have, of course, emerged to play a vital role without any existing institutional support, such as groups creating PPE for struggling hospitals, and communities in India and Nepal tracking oxygen supplies and hospital bed availability. Many of these new groups should be supported so that they can mobilise swiftly in future emergencies.

On top of that, greater proactive investment, following the lead of organisations like the Omidyar Network, should now be directed towards community infrastructure. And government institutions should acknowledge that it’s currently too difficult for community projects to connect into institutions. If they’re excluded from formal planning, such groups can’t offer their collective intelligence for the collective good.

Harnessing collective intelligence

At its best, collective intelligence can help us respond to crises with greater confidence, clarity and cooperation. But we need to start building and reinforcing these schemes and systems now – before the next crisis.

The pandemic has been tough. But it has also thrust our collective intelligence under the spotlight, whether through neighbourhood WhatsApp groups or international scientific research. As we move towards COVID recovery, placing our bets on new initiatives like the Global Pandemic Radar, we must ensure these lessons aren’t forgotten. We must now invest in the combined power of data, technology and people, which will help us avoid the next outbreak and counter society’s next big crisis.


This article is part of a series on recovering from the pandemic in a way that makes societies more resilient and able to deal with future challenges. It is supported by PreventionWeb, a platform from the UN Office for Disaster Risk Reduction. Read the rest of the coverage here.

Aleks Berditchevskaia receives funding from the United Nations Development Programme, the Economic and Social Research Council and the UK Humanitarian Innovation Hub.

Kathy Peach receives funding from the UK Humanitarian Innovation Hub, the United Nations Development Programme, the Omidyar Network, Wellcome and the Patrick J. McGovern Foundation. She is an adviser to the World Economic Forum. Kathy is a Labour party member.

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Fauci Deputy Warned Him Against Vaccine Mandates: Email

Fauci Deputy Warned Him Against Vaccine Mandates: Email

Authored by Zachary Stieber via The Epoch Times (emphasis ours),

Mandating COVID-19…

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Fauci Deputy Warned Him Against Vaccine Mandates: Email

Authored by Zachary Stieber via The Epoch Times (emphasis ours),

Mandating COVID-19 vaccination was a mistake due to ethical and other concerns, a top government doctor warned Dr. Anthony Fauci after Dr. Fauci promoted mass vaccination.

Coercing or forcing people to take a vaccine can have negative consequences from a biological, sociological, psychological, economical, and ethical standpoint and is not worth the cost even if the vaccine is 100% safe,” Dr. Matthew Memoli, director of the Laboratory of Infectious Diseases clinical studies unit at the U.S. National Institute of Allergy and Infectious Diseases (NIAID), told Dr. Fauci in an email.

“A more prudent approach that considers these issues would be to focus our efforts on those at high risk of severe disease and death, such as the elderly and obese, and do not push vaccination on the young and healthy any further.”

Dr. Anthony Fauci, ex-director of the National Institute of Allergy and Infectious Diseases (NIAID. in Washington on Jan. 8, 2024. (Madalina Vasiliu/The Epoch Times)

Employing that strategy would help prevent loss of public trust and political capital, Dr. Memoli said.

The email was sent on July 30, 2021, after Dr. Fauci, director of the NIAID, claimed that communities would be safer if more people received one of the COVID-19 vaccines and that mass vaccination would lead to the end of the COVID-19 pandemic.

“We’re on a really good track now to really crush this outbreak, and the more people we get vaccinated, the more assuredness that we’re going to have that we’re going to be able to do that,” Dr. Fauci said on CNN the month prior.

Dr. Memoli, who has studied influenza vaccination for years, disagreed, telling Dr. Fauci that research in the field has indicated yearly shots sometimes drive the evolution of influenza.

Vaccinating people who have not been infected with COVID-19, he said, could potentially impact the evolution of the virus that causes COVID-19 in unexpected ways.

“At best what we are doing with mandated mass vaccination does nothing and the variants emerge evading immunity anyway as they would have without the vaccine,” Dr. Memoli wrote. “At worst it drives evolution of the virus in a way that is different from nature and possibly detrimental, prolonging the pandemic or causing more morbidity and mortality than it should.”

The vaccination strategy was flawed because it relied on a single antigen, introducing immunity that only lasted for a certain period of time, Dr. Memoli said. When the immunity weakened, the virus was given an opportunity to evolve.

Some other experts, including virologist Geert Vanden Bossche, have offered similar views. Others in the scientific community, such as U.S. Centers for Disease Control and Prevention scientists, say vaccination prevents virus evolution, though the agency has acknowledged it doesn’t have records supporting its position.

Other Messages

Dr. Memoli sent the email to Dr. Fauci and two other top NIAID officials, Drs. Hugh Auchincloss and Clifford Lane. The message was first reported by the Wall Street Journal, though the publication did not publish the message. The Epoch Times obtained the email and 199 other pages of Dr. Memoli’s emails through a Freedom of Information Act request. There were no indications that Dr. Fauci ever responded to Dr. Memoli.

Later in 2021, the NIAID’s parent agency, the U.S. National Institutes of Health (NIH), and all other federal government agencies began requiring COVID-19 vaccination, under direction from President Joe Biden.

In other messages, Dr. Memoli said the mandates were unethical and that he was hopeful legal cases brought against the mandates would ultimately let people “make their own healthcare decisions.”

“I am certainly doing everything in my power to influence that,” he wrote on Nov. 2, 2021, to an unknown recipient. Dr. Memoli also disclosed that both he and his wife had applied for exemptions from the mandates imposed by the NIH and his wife’s employer. While her request had been granted, his had not as of yet, Dr. Memoli said. It’s not clear if it ever was.

According to Dr. Memoli, officials had not gone over the bioethics of the mandates. He wrote to the NIH’s Department of Bioethics, pointing out that the protection from the vaccines waned over time, that the shots can cause serious health issues such as myocarditis, or heart inflammation, and that vaccinated people were just as likely to spread COVID-19 as unvaccinated people.

He cited multiple studies in his emails, including one that found a resurgence of COVID-19 cases in a California health care system despite a high rate of vaccination and another that showed transmission rates were similar among the vaccinated and unvaccinated.

Dr. Memoli said he was “particularly interested in the bioethics of a mandate when the vaccine doesn’t have the ability to stop spread of the disease, which is the purpose of the mandate.”

The message led to Dr. Memoli speaking during an NIH event in December 2021, several weeks after he went public with his concerns about mandating vaccines.

“Vaccine mandates should be rare and considered only with a strong justification,” Dr. Memoli said in the debate. He suggested that the justification was not there for COVID-19 vaccines, given their fleeting effectiveness.

Julie Ledgerwood, another NIAID official who also spoke at the event, said that the vaccines were highly effective and that the side effects that had been detected were not significant. She did acknowledge that vaccinated people needed boosters after a period of time.

The NIH, and many other government agencies, removed their mandates in 2023 with the end of the COVID-19 public health emergency.

A request for comment from Dr. Fauci was not returned. Dr. Memoli told The Epoch Times in an email he was “happy to answer any questions you have” but that he needed clearance from the NIAID’s media office. That office then refused to give clearance.

Dr. Jay Bhattacharya, a professor of health policy at Stanford University, said that Dr. Memoli showed bravery when he warned Dr. Fauci against mandates.

“Those mandates have done more to demolish public trust in public health than any single action by public health officials in my professional career, including diminishing public trust in all vaccines.” Dr. Bhattacharya, a frequent critic of the U.S. response to COVID-19, told The Epoch Times via email. “It was risky for Dr. Memoli to speak publicly since he works at the NIH, and the culture of the NIH punishes those who cross powerful scientific bureaucrats like Dr. Fauci or his former boss, Dr. Francis Collins.”

Tyler Durden Mon, 03/11/2024 - 17:40

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Government

Trump “Clearly Hasn’t Learned From His COVID-Era Mistakes”, RFK Jr. Says

Trump "Clearly Hasn’t Learned From His COVID-Era Mistakes", RFK Jr. Says

Authored by Jeff Louderback via The Epoch Times (emphasis ours),

President…

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Trump "Clearly Hasn't Learned From His COVID-Era Mistakes", RFK Jr. Says

Authored by Jeff Louderback via The Epoch Times (emphasis ours),

President Joe Biden claimed that COVID vaccines are now helping cancer patients during his State of the Union address on March 7, but it was a response on Truth Social from former President Donald Trump that drew the ire of independent presidential candidate Robert F. Kennedy Jr.

Robert F. Kennedy Jr. holds a voter rally in Grand Rapids, Mich., on Feb. 10, 2024. (Mitch Ranger for The Epoch Times)

During the address, President Biden said: “The pandemic no longer controls our lives. The vaccines that saved us from COVID are now being used to help beat cancer, turning setback into comeback. That’s what America does.”

President Trump wrote: “The Pandemic no longer controls our lives. The VACCINES that saved us from COVID are now being used to help beat cancer—turning setback into comeback. YOU’RE WELCOME JOE. NINE-MONTH APPROVAL TIME VS. 12 YEARS THAT IT WOULD HAVE TAKEN YOU.”

An outspoken critic of President Trump’s COVID response, and the Operation Warp Speed program that escalated the availability of COVID vaccines, Mr. Kennedy said on X, formerly known as Twitter, that “Donald Trump clearly hasn’t learned from his COVID-era mistakes.”

“He fails to recognize how ineffective his warp speed vaccine is as the ninth shot is being recommended to seniors. Even more troubling is the documented harm being caused by the shot to so many innocent children and adults who are suffering myocarditis, pericarditis, and brain inflammation,” Mr. Kennedy remarked.

“This has been confirmed by a CDC-funded study of 99 million people. Instead of bragging about its speedy approval, we should be honestly and transparently debating the abundant evidence that this vaccine may have caused more harm than good.

“I look forward to debating both Trump and Biden on Sept. 16 in San Marcos, Texas.”

Mr. Kennedy announced in April 2023 that he would challenge President Biden for the 2024 Democratic Party presidential nomination before declaring his run as an independent last October, claiming that the Democrat National Committee was “rigging the primary.”

Since the early stages of his campaign, Mr. Kennedy has generated more support than pundits expected from conservatives, moderates, and independents resulting in speculation that he could take votes away from President Trump.

Many Republicans continue to seek a reckoning over the government-imposed pandemic lockdowns and vaccine mandates.

President Trump’s defense of Operation Warp Speed, the program he rolled out in May 2020 to spur the development and distribution of COVID-19 vaccines amid the pandemic, remains a sticking point for some of his supporters.

Vice President Mike Pence (L) and President Donald Trump deliver an update on Operation Warp Speed in the Rose Garden of the White House in Washington on Nov. 13, 2020. (Mandel Ngan/AFP via Getty Images)

Operation Warp Speed featured a partnership between the government, the military, and the private sector, with the government paying for millions of vaccine doses to be produced.

President Trump released a statement in March 2021 saying: “I hope everyone remembers when they’re getting the COVID-19 Vaccine, that if I wasn’t President, you wouldn’t be getting that beautiful ‘shot’ for 5 years, at best, and probably wouldn’t be getting it at all. I hope everyone remembers!”

President Trump said about the COVID-19 vaccine in an interview on Fox News in March 2021: “It works incredibly well. Ninety-five percent, maybe even more than that. I would recommend it, and I would recommend it to a lot of people that don’t want to get it and a lot of those people voted for me, frankly.

“But again, we have our freedoms and we have to live by that and I agree with that also. But it’s a great vaccine, it’s a safe vaccine, and it’s something that works.”

On many occasions, President Trump has said that he is not in favor of vaccine mandates.

An environmental attorney, Mr. Kennedy founded Children’s Health Defense, a nonprofit that aims to end childhood health epidemics by promoting vaccine safeguards, among other initiatives.

Last year, Mr. Kennedy told podcaster Joe Rogan that ivermectin was suppressed by the FDA so that the COVID-19 vaccines could be granted emergency use authorization.

He has criticized Big Pharma, vaccine safety, and government mandates for years.

Since launching his presidential campaign, Mr. Kennedy has made his stances on the COVID-19 vaccines, and vaccines in general, a frequent talking point.

“I would argue that the science is very clear right now that they [vaccines] caused a lot more problems than they averted,” Mr. Kennedy said on Piers Morgan Uncensored last April.

“And if you look at the countries that did not vaccinate, they had the lowest death rates, they had the lowest COVID and infection rates.”

Additional data show a “direct correlation” between excess deaths and high vaccination rates in developed countries, he said.

President Trump and Mr. Kennedy have similar views on topics like protecting the U.S.-Mexico border and ending the Russia-Ukraine war.

COVID-19 is the topic where Mr. Kennedy and President Trump seem to differ the most.

Former President Donald Trump intended to “drain the swamp” when he took office in 2017, but he was “intimidated by bureaucrats” at federal agencies and did not accomplish that objective, Mr. Kennedy said on Feb. 5.

Speaking at a voter rally in Tucson, where he collected signatures to get on the Arizona ballot, the independent presidential candidate said President Trump was “earnest” when he vowed to “drain the swamp,” but it was “business as usual” during his term.

John Bolton, who President Trump appointed as a national security adviser, is “the template for a swamp creature,” Mr. Kennedy said.

Scott Gottlieb, who President Trump named to run the FDA, “was Pfizer’s business partner” and eventually returned to Pfizer, Mr. Kennedy said.

Mr. Kennedy said that President Trump had more lobbyists running federal agencies than any president in U.S. history.

“You can’t reform them when you’ve got the swamp creatures running them, and I’m not going to do that. I’m going to do something different,” Mr. Kennedy said.

During the COVID-19 pandemic, President Trump “did not ask the questions that he should have,” he believes.

President Trump “knew that lockdowns were wrong” and then “agreed to lockdowns,” Mr. Kennedy said.

He also “knew that hydroxychloroquine worked, he said it,” Mr. Kennedy explained, adding that he was eventually “rolled over” by Dr. Anthony Fauci and his advisers.

President Donald Trump greets the crowd before he leaves at the Operation Warp Speed Vaccine Summit in Washington on Dec. 8, 2020. (Tasos Katopodis/Getty Images)

MaryJo Perry, a longtime advocate for vaccine choice and a Trump supporter, thinks votes will be at a premium come Election Day, particularly because the independent and third-party field is becoming more competitive.

Ms. Perry, president of Mississippi Parents for Vaccine Rights, believes advocates for medical freedom could determine who is ultimately president.

She believes that Mr. Kennedy is “pulling votes from Trump” because of the former president’s stance on the vaccines.

“People care about medical freedom. It’s an important issue here in Mississippi, and across the country,” Ms. Perry told The Epoch Times.

“Trump should admit he was wrong about Operation Warp Speed and that COVID vaccines have been dangerous. That would make a difference among people he has offended.”

President Trump won’t lose enough votes to Mr. Kennedy about Operation Warp Speed and COVID vaccines to have a significant impact on the election, Ohio Republican strategist Wes Farno told The Epoch Times.

President Trump won in Ohio by eight percentage points in both 2016 and 2020. The Ohio Republican Party endorsed President Trump for the nomination in 2024.

“The positives of a Trump presidency far outweigh the negatives,” Mr. Farno said. “People are more concerned about their wallet and the economy.

“They are asking themselves if they were better off during President Trump’s term compared to since President Biden took office. The answer to that question is obvious because many Americans are struggling to afford groceries, gas, mortgages, and rent payments.

“America needs President Trump.”

Multiple national polls back Mr. Farno’s view.

As of March 6, the RealClearPolitics average of polls indicates that President Trump has 41.8 percent support in a five-way race that includes President Biden (38.4 percent), Mr. Kennedy (12.7 percent), independent Cornel West (2.6 percent), and Green Party nominee Jill Stein (1.7 percent).

A Pew Research Center study conducted among 10,133 U.S. adults from Feb. 7 to Feb. 11 showed that Democrats and Democrat-leaning independents (42 percent) are more likely than Republicans and GOP-leaning independents (15 percent) to say they have received an updated COVID vaccine.

The poll also reported that just 28 percent of adults say they have received the updated COVID inoculation.

The peer-reviewed multinational study of more than 99 million vaccinated people that Mr. Kennedy referenced in his X post on March 7 was published in the Vaccine journal on Feb. 12.

It aimed to evaluate the risk of 13 adverse events of special interest (AESI) following COVID-19 vaccination. The AESIs spanned three categories—neurological, hematologic (blood), and cardiovascular.

The study reviewed data collected from more than 99 million vaccinated people from eight nations—Argentina, Australia, Canada, Denmark, Finland, France, New Zealand, and Scotland—looking at risks up to 42 days after getting the shots.

Three vaccines—Pfizer and Moderna’s mRNA vaccines as well as AstraZeneca’s viral vector jab—were examined in the study.

Researchers found higher-than-expected cases that they deemed met the threshold to be potential safety signals for multiple AESIs, including for Guillain-Barre syndrome (GBS), cerebral venous sinus thrombosis (CVST), myocarditis, and pericarditis.

A safety signal refers to information that could suggest a potential risk or harm that may be associated with a medical product.

The study identified higher incidences of neurological, cardiovascular, and blood disorder complications than what the researchers expected.

President Trump’s role in Operation Warp Speed, and his continued praise of the COVID vaccine, remains a concern for some voters, including those who still support him.

Krista Cobb is a 40-year-old mother in western Ohio. She voted for President Trump in 2020 and said she would cast her vote for him this November, but she was stunned when she saw his response to President Biden about the COVID-19 vaccine during the State of the Union address.

I love President Trump and support his policies, but at this point, he has to know they [advisers and health officials] lied about the shot,” Ms. Cobb told The Epoch Times.

“If he continues to promote it, especially after all of the hearings they’ve had about it in Congress, the side effects, and cover-ups on Capitol Hill, at what point does he become the same as the people who have lied?” Ms. Cobb added.

“I think he should distance himself from talk about Operation Warp Speed and even admit that he was wrong—that the vaccines have not had the impact he was told they would have. If he did that, people would respect him even more.”

Tyler Durden Mon, 03/11/2024 - 17:00

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International

The next pandemic? It’s already here for Earth’s wildlife

Bird flu is decimating species already threatened by climate change and habitat loss.

I am a conservation biologist who studies emerging infectious diseases. When people ask me what I think the next pandemic will be I often say that we are in the midst of one – it’s just afflicting a great many species more than ours.

I am referring to the highly pathogenic strain of avian influenza H5N1 (HPAI H5N1), otherwise known as bird flu, which has killed millions of birds and unknown numbers of mammals, particularly during the past three years.

This is the strain that emerged in domestic geese in China in 1997 and quickly jumped to humans in south-east Asia with a mortality rate of around 40-50%. My research group encountered the virus when it killed a mammal, an endangered Owston’s palm civet, in a captive breeding programme in Cuc Phuong National Park Vietnam in 2005.

How these animals caught bird flu was never confirmed. Their diet is mainly earthworms, so they had not been infected by eating diseased poultry like many captive tigers in the region.

This discovery prompted us to collate all confirmed reports of fatal infection with bird flu to assess just how broad a threat to wildlife this virus might pose.

This is how a newly discovered virus in Chinese poultry came to threaten so much of the world’s biodiversity.

H5N1 originated on a Chinese poultry farm in 1997. ChameleonsEye/Shutterstock

The first signs

Until December 2005, most confirmed infections had been found in a few zoos and rescue centres in Thailand and Cambodia. Our analysis in 2006 showed that nearly half (48%) of all the different groups of birds (known to taxonomists as “orders”) contained a species in which a fatal infection of bird flu had been reported. These 13 orders comprised 84% of all bird species.

We reasoned 20 years ago that the strains of H5N1 circulating were probably highly pathogenic to all bird orders. We also showed that the list of confirmed infected species included those that were globally threatened and that important habitats, such as Vietnam’s Mekong delta, lay close to reported poultry outbreaks.

Mammals known to be susceptible to bird flu during the early 2000s included primates, rodents, pigs and rabbits. Large carnivores such as Bengal tigers and clouded leopards were reported to have been killed, as well as domestic cats.

Our 2006 paper showed the ease with which this virus crossed species barriers and suggested it might one day produce a pandemic-scale threat to global biodiversity.

Unfortunately, our warnings were correct.

A roving sickness

Two decades on, bird flu is killing species from the high Arctic to mainland Antarctica.

In the past couple of years, bird flu has spread rapidly across Europe and infiltrated North and South America, killing millions of poultry and a variety of bird and mammal species. A recent paper found that 26 countries have reported at least 48 mammal species that have died from the virus since 2020, when the latest increase in reported infections started.

Not even the ocean is safe. Since 2020, 13 species of aquatic mammal have succumbed, including American sea lions, porpoises and dolphins, often dying in their thousands in South America. A wide range of scavenging and predatory mammals that live on land are now also confirmed to be susceptible, including mountain lions, lynx, brown, black and polar bears.

The UK alone has lost over 75% of its great skuas and seen a 25% decline in northern gannets. Recent declines in sandwich terns (35%) and common terns (42%) were also largely driven by the virus.

Scientists haven’t managed to completely sequence the virus in all affected species. Research and continuous surveillance could tell us how adaptable it ultimately becomes, and whether it can jump to even more species. We know it can already infect humans – one or more genetic mutations may make it more infectious.

At the crossroads

Between January 1 2003 and December 21 2023, 882 cases of human infection with the H5N1 virus were reported from 23 countries, of which 461 (52%) were fatal.

Of these fatal cases, more than half were in Vietnam, China, Cambodia and Laos. Poultry-to-human infections were first recorded in Cambodia in December 2003. Intermittent cases were reported until 2014, followed by a gap until 2023, yielding 41 deaths from 64 cases. The subtype of H5N1 virus responsible has been detected in poultry in Cambodia since 2014. In the early 2000s, the H5N1 virus circulating had a high human mortality rate, so it is worrying that we are now starting to see people dying after contact with poultry again.

It’s not just H5 subtypes of bird flu that concern humans. The H10N1 virus was originally isolated from wild birds in South Korea, but has also been reported in samples from China and Mongolia.

Recent research found that these particular virus subtypes may be able to jump to humans after they were found to be pathogenic in laboratory mice and ferrets. The first person who was confirmed to be infected with H10N5 died in China on January 27 2024, but this patient was also suffering from seasonal flu (H3N2). They had been exposed to live poultry which also tested positive for H10N5.

Species already threatened with extinction are among those which have died due to bird flu in the past three years. The first deaths from the virus in mainland Antarctica have just been confirmed in skuas, highlighting a looming threat to penguin colonies whose eggs and chicks skuas prey on. Humboldt penguins have already been killed by the virus in Chile.

A colony of king penguins.
Remote penguin colonies are already threatened by climate change. AndreAnita/Shutterstock

How can we stem this tsunami of H5N1 and other avian influenzas? Completely overhaul poultry production on a global scale. Make farms self-sufficient in rearing eggs and chicks instead of exporting them internationally. The trend towards megafarms containing over a million birds must be stopped in its tracks.

To prevent the worst outcomes for this virus, we must revisit its primary source: the incubator of intensive poultry farms.

Diana Bell does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

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