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Municipal Water and Wastewater Treatment Equipment Market Size to Increase by USD 16.02 Billion from 2021 to 2026| Technavio

Municipal Water and Wastewater Treatment Equipment Market Size to Increase by USD 16.02 Billion from 2021 to 2026| Technavio
PR Newswire
NEW YORK, May 23, 2022

NEW YORK, May 23, 2022 /PRNewswire/ — Technavio categorizes the municipal water and was…

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Municipal Water and Wastewater Treatment Equipment Market Size to Increase by USD 16.02 Billion from 2021 to 2026| Technavio

PR Newswire

NEW YORK, May 23, 2022 /PRNewswire/ -- Technavio categorizes the municipal water and wastewater treatment equipment market as a part of the global utility market. The municipal water and wastewater treatment equipment market research report provides valuable insights on the post-COVID-19 impact on the market, which will help companies evaluate their business approaches. 

Municipal Water and Wastewater Treatment Equipment Market: Key Drivers

The increase in demand for reclaimed water is driving the municipal water and wastewater treatment equipment market. The significant increase in population has led to growing pressure on natural water resources. Also, the increase in demand for organic foods and naturally grown grains is leading to the higher requirement of water for irrigation. An assessment published by the European Environment Agency (EEA) in October 2021 presents the current state of water stress in Europe with an aim to focus on managing water availability risks under the impacts of climate change. 

View market report outlook to learn more about factors influencing the market.

Municipal Water and Wastewater Treatment Equipment Market: Key Trends

The introduction of advanced membrane technologies is expected to positively impact the municipal water and wastewater treatment equipment market during the forecast period.  Membrane water treatment technology gained popularity and became affordable over the last three decades. These technologies are used for ultra-purification of the water. Based on the pore sizes, the technology is classified into microfiltration membrane (MF), reverse osmosis membrane (RO), microfiltration membrane (MF), ultrafiltration membrane (UF), and nanofiltration membrane (NF). The fabricated nanoporous membranes are used to remove various water pollutants, including metallic ions, salt, biological substrates, nanoparticles, and organic chemicals. 

Vendor Insights

The report identifies the following as the dominant vendors in the market:

  • 3M Corp.
  • Aquatech International LLC
  • Chembond Chemicals Ltd.
  • Culligan International Co.
  • Danaher Corp.
  • Ecolab Inc.
  • Evoqua Water Technologies LLC
  • General Electric Co.
  • Kuraray Co. Ltd.
  • Kurita Water Industries Ltd.
  • Mott MacDonald
  • Pentair Plc
  • SUEZ WTS USA Inc.
  • The Dow Chemical Co.
  • Thermax Ltd.
  • Thermo Fisher Scientific Inc.
  • Toray Industries Inc.
  • Veolia Environnement Group
  • WABAG Group
  • Xylem Inc.

Product Insights and News

The municipal water and wastewater treatment equipment market forecast report offers in-depth insights into key vendor profiles. The profiles include information on the production, sustainability, and prospects of the leading companies. For instance, 3M Corp., a leading vendor, offers membrane modules for ultrafiltration which are used to remove turbidity, suspended solids, and pathogens in order to improve the effluent quality of wastewater, thus can be reused in various applications. The company also offers industrial abrasives and finishing for metalworking applications, closure systems for personal hygiene products, autobody repair solutions, masking, and packaging materials.

Learn more about the vendors in the market as you download your sample copy

APAC's Contribution to Municipal Water and Wastewater Treatment Equipment Market

The increased demand for water for drinking as well as water for domestic usage due to urbanization and rapid population growth is expected to facilitate the municipal water and wastewater treatment equipment market growth in APAC over the forecast period. The region is expected to contribute to 37% of market growth as countries such as China and Japan are the key markets for municipal water and wastewater treatment equipment market. Market growth in APAC will be faster than the growth of the market in other regions.

Download your sample copy and know more about the market contribution in APAC

Municipal Water and Wastewater Treatment Equipment Market Scope

Report Coverage

Details

Page number

120

Base year

2021

Forecast period

2022-2026

Growth momentum & CAGR

Accelerate at a CAGR of 4.84%

Market growth 2022-2026

$ 16.02 billion

Market structure

Fragmented

YoY growth (%)

4.25

Regional analysis

APAC, North America, Europe, Middle East and Africa, and South America

Performing market contribution

APAC at 49%

Key consumer countries

US, China, Japan, France, and Brazil

Competitive landscape

Leading companies, Competitive strategies, Consumer engagement scope

Key companies profiled

3M Corp., Aquatech International LLC, Chembond Chemicals Ltd., Culligan International Co., Danaher Corp., Ecolab Inc., Evoqua Water Technologies LLC, General Electric Co., Kuraray Co. Ltd., Kurita Water Industries Ltd., Mott MacDonald, Pentair Plc, SUEZ WTS USA Inc., The Dow Chemical Co., Thermax Ltd., Thermo Fisher Scientific Inc., Toray Industries Inc., Veolia Environnement Group, WABAG Group, and Xylem Inc.

Market dynamics

Parent market analysis, Market growth inducers and obstacles, Fast-growing and slow-growing segment analysis, COVID 19 impact and recovery analysis and future consumer dynamics, Market condition analysis for forecast period

Customization purview

If our report has not included the data that you are looking for, you can reach out to our analysts and get segments customized.

Get your report sample copy to unlock scope and parent market analysis insights

Market Segmentation

The municipal water and wastewater treatment equipment market is divided by application into wastewater treatment segment and water treatment segment. The municipal water and wastewater treatment segment is expected to be the major contributor to the market. Wastewater needs to be treated for its usage for residential and industrial purposes as it contains several dissolved toxin oxides and hazardous elements.

Key Highlights

  • CAGR of the market during the forecast period 2022-2026
  • Comprehensive details of factors that will challenge the growth of municipal water and wastewater treatment equipment market vendors
  • Accurate predictions on upcoming trends and changes in consumer behavior
  • Detailed information on factors that will drive municipal water and wastewater treatment equipment market growth during the next five years
  • Precise estimation of the municipal water and wastewater treatment equipment market size and its contribution to the parent market
  • The growth of the municipal water and wastewater treatment equipment industry across APAC, North America, Europe, Middle East and Africa, and South America

Related Reports:

Rainwater Harvesting Systems Market by End-user and Geography - Forecast and Analysis 2022-2026 Download your sample

Produced Water Treatment Market by Application and Geography - Forecast and Analysis 2021-2025 Download your sample

Table of Contents

1 Executive Summary

  • 1.1 Market overview
    • Exhibit 01: Executive Summary – Chart on Market Overview
    • Exhibit 02: Executive Summary – Data Table on Market Overview
    • Exhibit 03: Executive Summary – Chart on Global Market Characteristics
    • Exhibit 04: Executive Summary – Chart on Market by Geography
    • Exhibit 05: Executive Summary – Chart on Market Segmentation by Application
    • Exhibit 06: Executive Summary – Chart on Incremental Growth
    • Exhibit 07: Executive Summary – Data Table on Incremental Growth
    • Exhibit 08: Executive Summary – Chart on Vendor Market Positioning

2 Market Landscape

  • 2.1 Market ecosystem
    • Exhibit 09: Parent market
    • Exhibit 10: Market Characteristics

3 Market Sizing

  • 3.1 Market definition
    • Exhibit 11: Offerings of vendors included in the market definition
  • 3.2 Market segment analysis
    • Exhibit 12: Market segments
  • 3.3 Market size 2021
  • 3.4 Market outlook: Forecast for 2021-2026
    • Exhibit 13: Chart on Global - Market size and forecast 2021-2026 ($ million)
    • Exhibit 14: Data Table on Global - Market size and forecast 2021-2026 ($ million)
    • Exhibit 15: Chart on Global Market: Year-over-year growth 2021-2026 (%)
    • Exhibit 16: Data Table on Global Market: Year-over-year growth 2021-2026 (%)

4 Five Forces Analysis

  • 4.1 Five forces summary
    • Exhibit 17: Five forces analysis - Comparison between2021 and 2026
  • 4.2 Bargaining power of buyers
    • Exhibit 18: Chart on Bargaining power of buyers – Impact of key factors 2021 and 2026
  • 4.3 Bargaining power of suppliers
    • Exhibit 19: Bargaining power of suppliers – Impact of key factors in 2021 and 2026
  • 4.4 Threat of new entrants
    • Exhibit 20: Threat of new entrants – Impact of key factors in 2021 and 2026
  • 4.5 Threat of substitutes
    • Exhibit 21: Threat of substitutes – Impact of key factors in 2021 and 2026
  • 4.6 Threat of rivalry
    • Exhibit 22: Threat of rivalry – Impact of key factors in 2021 and 2026
  • 4.7 Market condition
    • Exhibit 23: Chart on Market condition - Five forces 2021 and 2026

5 Market Segmentation by Application

  • 5.1 Market segments
    • Exhibit 24: Chart on Application - Market share 2021-2026 (%)
    • Exhibit 25: Data Table on Application - Market share 2021-2026 (%)
  • 5.2 Comparison by Application
    • Exhibit 26: Chart on Comparison by Application
    • Exhibit 27: Data Table on Comparison by Application
  • 5.3 Wastewater treatment - Market size and forecast 2021-2026
    • Exhibit 28: Chart on Wastewater treatment - Market size and forecast 2021-2026 ($ million)
    • Exhibit 29: Data Table on Wastewater treatment - Market size and forecast 2021-2026 ($ million)
    • Exhibit 30: Chart on Wastewater treatment - Year-over-year growth 2021-2026 (%)
    • Exhibit 31: Data Table on Wastewater treatment - Year-over-year growth 2021-2026 (%)
  • 5.4 Water treatment - Market size and forecast 2021-2026
    • Exhibit 32: Chart on Water treatment - Market size and forecast 2021-2026 ($ million)
    • Exhibit 33: Data Table on Water treatment - Market size and forecast 2021-2026 ($ million)
    • Exhibit 34: Chart on Water treatment - Year-over-year growth 2021-2026 (%)
    • Exhibit 35: Data Table on Water treatment - Year-over-year growth 2021-2026 (%)
  • 5.5 Market opportunity by Application
    • Exhibit 36: Market opportunity by Application ($ million)

6 Customer Landscape

  • 6.1 Customer landscape overview
    • Exhibit 37: Analysis of price sensitivity, lifecycle, customer purchase basket, adoption rates, and purchase criteria

7 Geographic Landscape

  • 7.1 Geographic segmentation
    • Exhibit 38: Chart on Market share by geography 2021-2026 (%)
    • Exhibit 39: Data Table on Market share by geography 2021-2026 (%)
  • 7.2 Geographic comparison
    • Exhibit 40: Chart on Geographic comparison
    • Exhibit 41: Data Table on Geographic comparison
  • 7.3 APAC - Market size and forecast 2021-2026
    • Exhibit 42: Chart on APAC - Market size and forecast 2021-2026 ($ million)
    • Exhibit 43: Data Table on APAC - Market size and forecast 2021-2026 ($ million)
    • Exhibit 44: Chart on APAC - Year-over-year growth 2021-2026 (%)
    • Exhibit 45: Data Table on APAC - Year-over-year growth 2021-2026 (%)
  • 7.4 North America - Market size and forecast 2021-2026
    • Exhibit 46: Chart on North America - Market size and forecast 2021-2026 ($ million)
    • Exhibit 47: Data Table on North America - Market size and forecast 2021-2026 ($ million)
    • Exhibit 48: Chart on North America - Year-over-year growth 2021-2026 (%)
    • Exhibit 49: Data Table on North America - Year-over-year growth 2021-2026 (%)
  • 7.5 Europe - Market size and forecast 2021-2026
    • Exhibit 50: Chart on Europe - Market size and forecast 2021-2026 ($ million)
    • Exhibit 51: Data Table on Europe - Market size and forecast 2021-2026 ($ million)
    • Exhibit 52: Chart on Europe - Year-over-year growth 2021-2026 (%)
    • Exhibit 53: Data Table on Europe - Year-over-year growth 2021-2026 (%)
  • 7.6 Middle East and Africa - Market size and forecast 2021-2026
    • Exhibit 54: Chart on Middle East and Africa - Market size and forecast 2021-2026 ($ million)
    • Exhibit 55: Data Table on Middle East and Africa - Market size and forecast 2021-2026 ($ million)
    • Exhibit 56: Chart on Middle East and Africa - Year-over-year growth 2021-2026 (%)
    • Exhibit 57: Data Table on Middle East and Africa - Year-over-year growth 2021-2026 (%)
  • 7.7 South America - Market size and forecast 2021-2026
    • Exhibit 58: Chart on South America - Market size and forecast 2021-2026 ($ million)
    • Exhibit 59: Data Table on South America - Market size and forecast 2021-2026 ($ million)
    • Exhibit 60: Chart on South America - Year-over-year growth 2021-2026 (%)
    • Exhibit 61: Data Table on South America - Year-over-year growth 2021-2026 (%)
  • 7.8 China - Market size and forecast 2021-2026
    • Exhibit 62: Chart on China - Market size and forecast 2021-2026 ($ million)
    • Exhibit 63: Data Table on China - Market size and forecast 2021-2026 ($ million)
    • Exhibit 64: Chart on China - Year-over-year growth 2021-2026 (%)
    • Exhibit 65: Data Table on China - Year-over-year growth 2021-2026 (%)
  • 7.9 US - Market size and forecast 2021-2026
    • Exhibit 66: Chart on US - Market size and forecast 2021-2026 ($ million)
    • Exhibit 67: Data Table on US - Market size and forecast 2021-2026 ($ million)
    • Exhibit 68: Chart on US - Year-over-year growth 2021-2026 (%)
    • Exhibit 69: Data Table on US - Year-over-year growth 2021-2026 (%)
  • 7.10 Japan - Market size and forecast 2021-2026
    • Exhibit 70: Chart on Japan - Market size and forecast 2021-2026 ($ million)
    • Exhibit 71: Data Table on Japan - Market size and forecast 2021-2026 ($ million)
    • Exhibit 72: Chart on Japan - Year-over-year growth 2021-2026 (%)
    • Exhibit 73: Data Table on Japan - Year-over-year growth 2021-2026 (%)
  • 7.11 France - Market size and forecast 2021-2026
    • Exhibit 74: Chart on France - Market size and forecast 2021-2026 ($ million)
    • Exhibit 75: Data Table on France - Market size and forecast 2021-2026 ($ million)
    • Exhibit 76: Chart on France - Year-over-year growth 2021-2026 (%)
    • Exhibit 77: Data Table on France - Year-over-year growth 2021-2026 (%)
  • 7.12 Brazil - Market size and forecast 2021-2026
    • Exhibit 78: Chart on Brazil - Market size and forecast 2021-2026 ($ million)
    • Exhibit 79: Data Table on Brazil - Market size and forecast 2021-2026 ($ million)
    • Exhibit 80: Chart on Brazil - Year-over-year growth 2021-2026 (%)
    • Exhibit 81: Data Table on Brazil - Year-over-year growth 2021-2026 (%)
  • 7.13 Market opportunity by geography
    • Exhibit 82: Market opportunity by geography ($ million)

8 Drivers, Challenges, and Trends

  • 8.1 Market drivers
  • 8.2 Market challenges
  • 8.3 Impact of drivers and challenges
    • Exhibit 83: Impact of drivers and challenges in 2021 and 2026
  • 8.4 Market trends

9 Vendor Landscape

  • 9.1 Overview
  • 9.2 Vendor landscape
    • Exhibit 84: Overview on Criticality of inputs and Factors of differentiation
  • 9.3 Landscape disruption
    • Exhibit 85: Overview on factors of disruption
  • 9.4 Industry risks
    • Exhibit 86: Impact of key risks on business

10 Vendor Analysis

  • 10.1 Vendors covered
    • Exhibit 87: Vendors covered
  • 10.2 Market positioning of vendors
    • Exhibit 88: Matrix on vendor position and classification
  • 10.3 3M Corp.
    • Exhibit 89: 3M Corp. - Overview
    • Exhibit 90: 3M Corp. - Business segments
    • Exhibit 91: 3M Corp. - Key news
    • Exhibit 92: 3M Corp. - Key offerings
    • Exhibit 93: 3M Corp. - Segment focus
  • 10.4 Aquatech International LLC
    • Exhibit 94: Aquatech International LLC - Overview
    • Exhibit 95: Aquatech International LLC - Product / Service
    • Exhibit 96: Aquatech International LLC - Key offerings
  • 10.5 Ecolab Inc.
    • Exhibit 97: Ecolab Inc. - Overview
    • Exhibit 98: Ecolab Inc. - Business segments
    • Exhibit 99: Ecolab Inc. - Key news
    • Exhibit 100: Ecolab Inc. - Key offerings
    • Exhibit 101: Ecolab Inc. - Segment focus
  • 10.6 Evoqua Water Technologies LLC
    • Exhibit 102: Evoqua Water Technologies LLC - Overview
    • Exhibit 103: Evoqua Water Technologies LLC - Business segments
    • Exhibit 104: Evoqua Water Technologies LLC - Key news
    • Exhibit 105: Evoqua Water Technologies LLC - Key offerings
    • Exhibit 106: Evoqua Water Technologies LLC - Segment focus
  • 10.7 General Electric Co.
    • Exhibit 107: General Electric Co. - Overview
    • Exhibit 108: General Electric Co. - Business segments
    • Exhibit 109: General Electric Co. - Key news
    • Exhibit 110: General Electric Co. - Key offerings
    • Exhibit 111: General Electric Co. - Segment focus
  • 10.8 Pentair Plc
    • Exhibit 112: Pentair Plc - Overview
    • Exhibit 113: Pentair Plc - Business segments
    • Exhibit 114: Pentair Plc - Key news
    • Exhibit 115: Pentair Plc - Key offerings
    • Exhibit 116: Pentair Plc - Segment focus
  • 10.9 SUEZ WTS USA Inc.
    • Exhibit 117: SUEZ WTS USA Inc. - Overview
    • Exhibit 118: SUEZ WTS USA Inc. - Product / Service
    • Exhibit 119: SUEZ WTS USA Inc. - Key offerings
  • 10.10 The Dow Chemical Co.
    • Exhibit 120: The Dow Chemical Co. - Overview
    • Exhibit 121: The Dow Chemical Co. - Business segments
    • Exhibit 122: The Dow Chemical Co. - Key offerings
    • Exhibit 123: The Dow Chemical Co. - Segment focus
  • 10.11 Veolia Environnement Group
    • Exhibit 124: Veolia Environnement Group - Overview
    • Exhibit 125: Veolia Environnement Group - Business segments
    • Exhibit 126: Veolia Environnement Group - Key offerings
    • Exhibit 127: Veolia Environnement Group - Segment focus
  • 10.12 Xylem Inc.
    • Exhibit 128: Xylem Inc. - Overview
    • Exhibit 129: Xylem Inc. - Business segments
    • Exhibit 130: Xylem Inc. - Key offerings
    • Exhibit 131: Xylem Inc. - Segment focus

11 Appendix

  • 11.1 Scope of the report
  • 11.2 Inclusions and exclusions checklist
    • Exhibit 132: Inclusions checklist
    • Exhibit 133: Exclusions checklist
  • 11.3 Currency conversion rates for US$
    • Exhibit 134: Currency conversion rates for US$
  • 11.4 Research methodology
    • Exhibit 135: Research methodology
    • Exhibit 136: Validation techniques employed for market sizing
    • Exhibit 137: Information sources
  • 11.5 List of abbreviations
    • Exhibit 138: List of abbreviations

About Us
Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provide actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library and its client base consist of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

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Technavio Research
Jesse Maida
Media & Marketing Executive
US: +1 844 364 1100
UK: +44 203 893 3200
Email:media@technavio.com
Website: www.technavio.com/

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Economics

The One Housing Chart That Shows A ‘Buyer’s Market’ Has Returned

The One Housing Chart That Shows A ‘Buyer’s Market’ Has Returned

The red hot pandemic-era housing market is cooling as historically tight…

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The One Housing Chart That Shows A 'Buyer's Market' Has Returned

The red hot pandemic-era housing market is cooling as historically tight available inventory shows signs of reversing. 

An affordability crisis has removed millions of new home buyers as the number of active US listings soared 18.7% in June from a year earlier, the most significant increase in Realtor.com's data going back to 2017, according to Bloomberg. The days of insane bidding wars, waiving home inspections, and putting in an offer 20% or more over the list price appear to be over. In other words, a buyer's market could be emerging. 

"While we anticipate that more inventory will eventually cool the feverish pace of competition, the typical buyer has yet to see meaningful relief from quick-selling homes and record-high asking prices," said Danielle Hale, chief economist for Realtor.com. 

Austin, Texas; Phoenix, Arizona; and Raleigh, North Carolina saw active listings more than double from a year ago. Nashville, Tennessee, active listings jumped 86%, and 72% in the Riverside, California. 

The Federal Reserve's most aggressive tightening campaign sent the 30-year fixed-loan mortgage rate from 3% to over 6% this year (back in March, we warned coming rate explosion would trigger a housing affordability crisis), removing millions of new home buyers who can't afford the cost of homeownership as the median existing-home sales price was around $407k in May. 

Even though inventory is historically tight, supply is expected to increase in markets across the country as demand for loan applications among prospective buyers slumps. Fewer buyers equal more inventory. 

The takeaway is that inventory is rising as homes stay on the market longer because demand evaporated thanks to the housing affordability crisis -- this could mean a housing top is nearing. 

Tyler Durden Thu, 06/30/2022 - 18:50

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Economics

States Need To Avoid ‘Cures’ That Can Make Inflation Worse

States Need To Avoid ‘Cures’ That Can Make Inflation Worse

Authored by Regina M. Egea and Danielle Zanzalari via RealClearPolicy.com,

Across…

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States Need To Avoid 'Cures' That Can Make Inflation Worse

Authored by Regina M. Egea and Danielle Zanzalari via RealClearPolicy.com,

Across the United States, state governments are awash in cash. In a sharp contrast, American taxpayers are enduring a rate of inflation unseen in four decades, with the costs of everything from food to gasoline at record highs.

In our home state of New Jersey, Trenton is looking at an unprecedented surplus of $8 billion through a combination of increased tax revenue, federal pandemic aid and borrowing.

A natural impulse among residents and policymakers is to offer residents “relief” in the form of rebate checks.

The reality is that relying exclusively on rebates or direct cash transfers to individuals will only lead to more inflation as this puts more money in consumers’ hands exacerbating the same problem as today - too many dollars chasing too few goods.

Rather, it is prudent that states focus on long-term investment and responsible budgeting to ensure economic growth now and in the future. This is especially important in high tax, big spending states due to the greater flexibility in work arrangements that have exposed the reality that wealth is mobile.

With more residents fleeing high tax states to low tax states, states will need to reevaluate their tax and regulatory climate to stay competitive. 

Regulation can raise the costs for consumers and slow job growth. A series of studies shows the regulation raises prices and worsens poverty.

Working with local governments to revisit restrictive laws that contribute to higher housing prices, such as building height restrictions and zoning rules, as well as removing unnecessary restrictions on business operations will lead to more economic growth.

Another way states can aid productivity and long-term economic growth with their temporary budget surplus, is to fund training programs for middle-skilled jobs.

Nearly every industry has experienced labor shortages and that reality is especially acute in trades like auto, refrigeration, HVAC, electrical, welding, and manufacturing.

States can invest in these skills through high school and vocational school programs. With college borrowing costs astronomically high, this encourages individuals to pursue careers that are lucrative and budget friendly, as well as fill the over 75,000 job openings that our state of New Jersey is projected to need in just a few years.

To further long-term economic growth many states should also concentrate on fixing their unfunded pension liabilities for public employees. This impacts red and blue states alike, with massive liabilities in California ($1.53 trillion), Illinois ($533.72 billion), Texas ($529.70 billion), New York ($508.70 billion) and Ohio ($429.53 billion). Here in New Jersey, our liability is nearly $40,000 for every resident of the state, which can dramatically deter future growth. Beyond using some of states’ budget surplus to shore up pension liabilities, states should move public employees to defined contribution plans, which are used by more than 100 million Americans. These are found to have better investment returns than state-wide pension plans and cost taxpayers less.

Our final recommendation is perhaps our most important: Save for a rainy day. If the U.S. economy enters into a recession, this will mean fewer jobs and less tax revenue for states. To prepare for the future when states again face a budget shortfall, which may be sooner than we think, states should follow best practices of reserving 10% of their budget in a rainy day fund, to sustain essential programs should a downturn occur in the future.

As state leaders consider their budgets, they should focus on long-term economic growth initiatives. Proposals like funding middle-skilled job trainings ensure workers are ready for the next decade, whereas eliminating unnecessary regulations and focusing on pro-growth tax reforms encourages residents to build businesses and create jobs. Lastly, taking care of state finances by properly funding state employees’ retirement plans and saving for a rainy day will ensure that no state is left behind in the next economic downturn.

Tyler Durden Thu, 06/30/2022 - 17:50

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Spread & Containment

Aging-US | Time makes histone H3 modifications drift in mouse liver

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone…

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BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone H3 modifications drift in mouse liver.”

Credit: Hillje et al.

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone H3 modifications drift in mouse liver.”

Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.

“So far, no study discloses any drift of histone marks in mammals which is time-dependent or influenced by pro-longevity caloric restriction treatment.”

To detect the epigenetic drift of time passing, researchers—from Istituto di Ricovero e Cura a Carattere Scientifico, University of Urbino ‘Carlo Bo’, University of Milan, and University of Padua—determined the genome-wide distributions of mono- and tri-methylated lysine 4 and acetylated and tri-methylated lysine 27 of histone H3 in the livers of healthy 3, 6 and 12 months old C57BL/6 mice. 

“In this study, we used chromatin immunoprecipitation sequencing technology to acquire 108 high-resolution profiles of H3K4me3, H3K4me1, H3K27me3 and H3K27ac from the livers of mice aged between 3 months and 12 months and fed 30% caloric restriction diet (CR) or standard diet (SD).”

The comparison of different age profiles of histone H3 marks revealed global redistribution of histone H3 modifications with time, in particular in intergenic regions and near transcription start sites, as well as altered correlation between the profiles of different histone modifications. Moreover, feeding mice with caloric restriction diet, a treatment known to retard aging, reduced the extent of changes occurring during the first year of life in these genomic regions.

“In conclusion, while our data do not establish that the observed changes in H3 modification are causally involved in aging, they indicate age, buffered by caloric restriction, releases the histone H3 marking process of transcriptional suppression in gene desert regions of mouse liver genome most of which remain to be functionally understood.”

DOI: https://doi.org/10.18632/aging.204107 

Corresponding Author: Marco Giorgio – marco.giorgio@unipd.it 

Keywords: epigenetics, aging, histones, ChIP-seq, diet

Sign up for free Altmetric alerts about this article:  https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204107

About Aging-US:

Launched in 2009, Aging (Aging-US) publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

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For media inquiries, please contact media@impactjournals.com.

Aging (Aging-US) Journal Office
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Orchard Park, NY 14127
Phone: 1-800-922-0957, option 1

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