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Infrastructure Investment and Jobs Act: Stock Market Guide

Keep reading to learn more about the Infrastructure Investment and Jobs Act and how it could affect your portfolio below.
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The Infrastructure Investment and Jobs Act was passed last year as part of the President’s Build Back Better plan. Accordingly, the new bill authorizes funds to stimulate new building and restore America.

The infamous “infrastructure week” finally holds true to its promise to start building. In November, HR 3684, also known as the Infrastructure Investment and Jobs Act, was signed into law with both party’s support.

Above all, the bill intends to create jobs while stimulating the U.S. economy for years. At the same time, the jobs act may have bigger effects on the stock market and your portfolio. Learn more about the Infrastructure Investment and Jobs Act and how it could affect your portfolio below.

What Is the Infrastructure Investment and Jobs Act?

The Infrastructure Investment and Jobs Act (IIJA) is a $1.2 trillion bill passed into law in 2021. The administration calls it as a “once-in-a-generation investment.” And the largest of its kind in U.S. history.

With this in mind, the jobs act sets aside funds to advance several issues pressing the economy. For example, the bill (with Build Back Better) expects to add 1.5 million jobs every year until at least 2032.

The historic investment in America focuses on improving several aspects of the economy holding the nation back. By providing everyone with an opportunity, the country can advance as a whole.

Adam Smith, the ‘father of economics,’ famously said, “A nation is not made wealthy by the childish accumulation of shiny metals, but it enriched by the economic prosperity of its people.” While this may be true, with soaring inflation and an already huge deficit, will the bill do as it intends?

Where Are the Funds Going?

Below you will find a quick breakdown of the Infrastructure Investment and Jobs Act and where the funds are going.

  • $110 billion: Repair and rebuild roads and bridges. It also includes funds for other major projects to reduce accidents.
  • $73 billion: Funding to improve the electric grid and promote clean energy.
  • $66 billion: Railroad and freight funding to end Maintenance backlog and upgrade the network.
  • $65 billion: Broadband deployment to ensure every American has access to high-speed internet. It will also help lower service prices to make the internet more affordable.
  • $55 billion: Replace and rebuild lead water pipes to support clean drinking water.
  • $50 billion: To protect against the impacts of climate change such as droughts, fires, and floods. Moreover, the bill includes funds for protecting against cyber-attacks.
  • $42 billion: Airport improvements for runways, gates and terminals to improve air traffic.
  • $39 billion: Public transit upgrades, including multi-billion-dollar repairs and signal replacements.
  • $15 billion: To promote EV adoption, including funds to build a national EV charger network. Furthermore, half of the funds are replacing school buses with zero-emission, clean energy buses.

As you can see, the bill aims to close the widening income gap in America by providing equal access opportunities. Furthermore, the jobs act intends to ease supply chain issues, a key driver of inflation.

Will the Infrastructure Investment and Jobs Act Affect the Stock Market?

With an influx of money, several industries will likely see a boost in demand from the jobs act. For one thing, the infrastructure investment and jobs act injects $1.2 trillion into the economy over the next five years. With this in mind, the investment is the largest spending on rebuilding in decades.

Chief economist at Moody’s Analytics, Mark Zandi, says, “increasing infrastructure investment has significant macroeconomic benefits.” Citing positive effects on GDP and employment in the long run. If the bill helps stimulate growth, you can expect a few sectors and specific industries to benefit.

  • Materials: With the most significant funds for building and improving roads and bridges, materials can see a big boost in demand. More importantly, the White House requires all funds to be used on U.S. materials. For example, all iron, steel, manufactured products and construction materials will need to be domestic.
  • Transportation: The transportation sector is another area of focus with funding for railroads, ports and public transit. Not to mention the clean energy upgrades for buses.
  • Construction & Engineering: A good part of the 1.5 million jobs will be in the construction and engineering industries. With more output and government help, we could see profits rise.
  • Electric Vehicles: To boost EV adoption, the bill aims to create a national EV charging network. With this in mind, the investment can encourage more people to consider buying EVs.
  • Renewable Energy: The bill is a big win for renewable energy with $65 billion in funding to expand clean energy options.

Another key thing to consider is long-term trends. The IIJA lays the groundwork for a cleaner, more resilient future.

How Will It Be Paid For?

A major concern people have with the Infrastructure Investment and Jobs Act is the amount of money. For one thing, over $4.6 trillion has been spent so far in response to the pandemic. So, it’s reasonable to be skeptical of another massive spending bill.

But the administration has several ideas to pay for the spending. Here are a few estimates…

  1. About $210 billion in unused COVID-19 relief funds.
  2. $56 billion in economic growth assuming a 33% ROI.
  3. $53 billion from states unused federal UI supplement.
  4. $51 billion from delaying Medicare Part D rebate.
  5. $28 billion in fees from cryptocurrency
  6. $21 billion from higher GSE fees.
  7. $14 billion from reinstating superfund fees.
  8. $6 billion in sales from strategic oil reserves.

Furthermore, the broader agenda plans to raise taxes on corporations and high earners. As a result, the lower and middle class should benefit.

Infrastructure Investment and Jobs Act Summary

The Infrastructure Investment and Jobs Act is another step in President Biden’s Build Back Better plan. The new bill calls for a slew of new funds and programs to boost the economy while setting America on a path for sustained growth.

Through these new investments, several industries will see an influx of cash. For example, U.S. materials companies producing steel, iron, and other construction parts will likely see higher demand. On top of this, the bill advances issues like clean drinking water and internet access to provide equal opportunities to rural areas.

Will the new jobs act do as it intends and stimulate the economy? Or will it add further fuel to the fire known as inflation? So far, economists expect mild results, slight to no growth and little debt added.

The post Infrastructure Investment and Jobs Act: Stock Market Guide appeared first on Investment U.

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PR55α-controlled PP2A Inhibits p16 Expression and Blocks Cellular Senescence Induction

“Our results show that PR55α specifically reduces p16 expression […]” Credit: 2024 Palanivel et al. “Our results show that PR55α specifically…

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“Our results show that PR55α specifically reduces p16 expression […]”

Credit: 2024 Palanivel et al.

“Our results show that PR55α specifically reduces p16 expression […]”

BUFFALO, NY- March 19, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 5, entitled, “PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation.”

Cellular senescence is a permanent cell cycle arrest that can be triggered by both internal and external genotoxic stressors, such as telomere dysfunction and DNA damage. The execution of senescence is mainly by two pathways, p16/RB and p53/p21, which lead to CDK4/6 inhibition and RB activation to block cell cycle progression. While the regulation of p53/p21 signaling in response to DNA damage and other insults is well-defined, the regulation of the p16/RB pathway in response to various stressors remains poorly understood. 

In this new study, researchers Chitra Palanivel, Lepakshe S. V. Madduri, Ashley L. Hein, Christopher B. Jenkins, Brendan T. Graff, Alison L. Camero, Sumin Zhou, Charles A. Enke, Michel M. Ouellette, and Ying Yan from the University of Nebraska Medical Center report a novel function of PR55α, a regulatory subunit of PP2A Ser/Thr phosphatase, as a potent inhibitor of p16 expression and senescence induction by ionizing radiation (IR), such as γ-rays. 

“During natural aging, there is a gradual accumulation of p16-expressing senescent cells in tissues [76]. To investigate the significance of PR55α in this up-regulation of p16, we compared levels of the p16 and PR55α proteins in a panel of normal tissue specimens derived from young (≤43 y/o) and old (≥68 y/o) donors.”

The results show that ectopic PR55α expression in normal pancreatic cells inhibits p16 transcription, increases RB phosphorylation, and blocks IR-induced senescence. Conversely, PR55α-knockdown by shRNA in pancreatic cancer cells elevates p16 transcription, reduces RB phosphorylation, and triggers senescence induction after IR. Furthermore, this PR55α function in the regulation of p16 and senescence is p53-independent because it was unaffected by the mutational status of p53. Moreover, PR55α only affects p16 expression but not p14 (ARF) expression, which is also transcribed from the same CDKN2A locus but from an alternative promoter. In normal human tissues, levels of p16 and PR55α proteins were inversely correlated and mutually exclusive. 

“Collectively, these results describe a novel function of PR55α/PP2A in blocking p16/RB signaling and IR-induced cellular senescence.”
 

Read the full paper: DOI: https://doi.org/10.18632/aging.205619 

Corresponding Authors: Michel M. Ouellette, Ying Yan

Corresponding Emails: mouellet@unmc.edu, yyan@unmc.edu

Keywords: p16, p14, CDKN2A locus, p53, RB, PR55α, PP2A, γ-irradiation

Click here to sign up for free Altmetric alerts about this article.

 

About Aging:

Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer’s diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan. The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases.

Aging is indexed by PubMed/Medline (abbreviated as “Aging (Albany NY)”), PubMed Central, Web of Science: Science Citation Index Expanded (abbreviated as “Aging‐US” and listed in the Cell Biology and Geriatrics & Gerontology categories), Scopus (abbreviated as “Aging” and listed in the Cell Biology and Aging categories), Biological Abstracts, BIOSIS Previews, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science).

Please visit our website at www.Aging-US.com​​ and connect with us:

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For media inquiries, please contact media@impactjournals.com.

 

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Bolsonaro Indicted By Brazilian Police For Falsifying Covid-19 Vaccine Records

Bolsonaro Indicted By Brazilian Police For Falsifying Covid-19 Vaccine Records

Federal police in Brazil have indicted former President Jair…

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Bolsonaro Indicted By Brazilian Police For Falsifying Covid-19 Vaccine Records

Federal police in Brazil have indicted former President Jair Bolsonaro for falsifying his Covid-19 vaccine card in order to travel to the United States and elsewhere during the pandemic.

Federal prosecutors will review the indictment and decide whether to pursue the case - which would be the first time the former president has faced criminal charges.

According to the indictment, Bolsonaro ordered a top deputy to obtain falsified Covid-19 vaccine records of himself and his 13-year-old daughter in late 2022, right before he flew to Florida for a three-month stay following his election loss.

Brazilian police are also waiting to hear back from the US DOJ on whether Bolsonaro used said cards to enter the United States, which would open him up to further criminal charges, the NY Times reports.

Bolsonaro has repeatedly claimed not to have received the Covid-19 vaccine, but denies any involvement in a plan to falsify his vaccination records. A previous investigation by Brazil's comptroller general concluded that Bolsonaro's vaccination records were false.

The records show that Bolsonaro, a COVID-19 skeptic who publicly opposed the vaccine, received a dose of the immunizer in a public healthcare center in Sao Paulo in July 2021. [ZH: hilarious, Reuters calling the vaccine an 'immunizer.']

The investigation concluded, however, that the former president had left the city the previous day and didn't leave Brasilia until three days later, according to a statement.

The nurse listed in the records as having applied the vaccine on Bolsonaro denied doing so and was no longer working at the center. The listed vaccine lot was also not available on that date, the comptroller general's office said. -Reuters

"It's a selective investigation. I'm calm, I don't owe anything," Bolsonaro told Reuters. "The world knows that I didn't take the vaccine."

During the pandemic, Bolsonaro panned the vaccine - and instead insisted on alternative treatments such as Ivermectin, which has antiviral properties against Covid-19. For this, he was investigated by Brazil's congress, which recommended that the former president be charged with "crimes against humanity," among other things, for his actions during the pandemic.

In May, Brazilian police raided Bolsonaro's home, confiscating his cell phone and arresting one of his closest aides and two of his security cards in connection to the vaccine record investigation.

Brazil's electoral court ruled that Bolsonaro can't run for public office until 2030 after he suggested that the country's voting system was rigged. For that, he has to sit out the 2026 election.

Tyler Durden Tue, 03/19/2024 - 11:00

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Spread & Containment

TJ Maxx and Marshalls follow Costco and Target on upcoming closures

Many of these stores have information customers need to know.

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U.S. consumers have come to increasingly rely on the near ubiquity of convenience stores and big-box retailers. 

Many of us depend on these stores being open practically all day, every day, even during some of the biggest holidays. After all, Black Friday beckons retail stores to open just hours after a Thanksgiving Day dinner in hopes of attracting huge crowds of shoppers in search of early holiday sales. 

Related: Walmart announces more store closures for 2024

And it's largely true that before the covid pandemic most of our favorite stores were open all the time. Practically nothing — from inclement weather to bad news to holidays — could shut down a major operation like Walmart  (WMT)  or Target  (TGT)

Then the pandemic hit, and it turned everything we thought we knew about retail operations upside down. 

Everything from grocery stores to shopping malls shut down in an effort to contain potential spread. And when they finally reopened to the public, different stores took different precautionary measures. Some monitored how many shoppers were inside at once, while others implemented foot-traffic rules dictating where one could enter and exit an aisle. And almost every one of them mandated wearing masks at one point or another. 

Though these safety measures seem like a distant memory, one relic from the early 2020s remains firmly a part of our new American retail life. 

A woman in a face mask shopping in the HomeGoods kitchen aisle.

Jeff Greenberg/Getty Images

Store closures announced for spring 2024

Many retailers have learned to adapt after a volatile start to this third decade, and in many ways this requires serving customers better and treating employees better to retain a workforce. 

In some cases, the changes also reflect a change in shopping behavior, as more customers order online and leave more breathing room for brick-and-mortar operations. This also means more time for employees. 

Thanks to this, big retailers have recently changed how they operate, especially during holiday hours, with Walmart recently saying it would close during Thanksgiving to give employees more time to spend with loved ones.

"I am delighted to share that once again, we'll be closing our doors for Thanksgiving this year," Walmart U.S. CEO John Furner told associates in a video posted to Twitter in November. "Thanksgiving is such a special day during a very busy season. We want you to spend that day at home with family and loved ones." 

Other retailers have now followed suit, with Costco  (COST) , Aldi, and Target all saying they would close their doors for 24 hours on Easter Sunday, March 31. 

Now, the stores that operate under TJX Cos.  (TJX)  will also shut down during the holiday, including HomeGoods, TJ Maxx and Marshalls

Though it closed on Thanksgiving, Walmart says it will remain open for shoppers on Easter. 

Here's a list of stores that are closing for Easter 2024: 

  • Target
  • Costco
  • Aldi
  • TJ Maxx
  • Marshalls
  • HomeGoods
  • Publix
  • Macy's
  • Best Buy
  • Apple
  • ACE Hardware

Others are expected to remain open, including:

  • Walmart
  • Ikea
  • Petco
  • Home Depot

Most of the stores closing on Sunday will reopen for regular business hours on Monday. 

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