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Study finds unexpected prescription influencers in healthcare

Cate Evans, SVP group director, strategy at Havas Media Group, and Nick Lapolla, research director at MedSurvey tell
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Cate Evans, SVP group director, strategy at Havas Media Group, and Nick Lapolla, research director at MedSurvey tell us about a two-phase research study the companies recently performed to understand a patient’s prescription journey and who influences prescription-based decisions.

The healthcare landscape has shifted dramatically due to the pandemic. What was once usual practice for pharma – connecting with stakeholders through face-to-face interactions – has pivoted into the need to make meaningful relationships digitally.

But who does pharma need to reach to ensure these connections translate to increased knowledge and utilisation of its products?

To evaluate this question, Havas and MedSurvey performed a study on how the transformations within the healthcare system have affected the patient journey and who is most influential in prescribing decisions.

The study

Before beginning the study, researchers at Havas and MedSurvey hypothesised that it might be non-MDs who are spending more time with patients and having more in-depth conversations.

As a patient goes through their prescribing journey, they meet many different people, and one’s meeting with their doctor may be brief compared to the time spent with others.

From Havas Media Group’s view, Evans says the researchers wanted to focus on the question: when it comes to the prescribing journey, who could be the other people who have prescribing-type conversations and are influential in this process?

Lapolla notes that from the perspective of MedSurvey, one thing they often hear from their clients is how difficult it can be getting research done to find out how to have a more significant reach in the market.

“So many more drugs are coming to market, and if you look at what the FDA has done over the last five years with approvals versus the actual pool of individuals to speak with, there’s a vast change in the need and the demand,” Lapolla states.

“But it’s not as if we’re getting tons more physicians coming into the market. So, from that standpoint, to be able to have a bigger reach and to understand more fully that holistic view was important.”

The research began with a qualitative study consisting of 60-minute interviews with six healthcare providers, including two MDs, two physician assistants/registered nurses, and two pharmacists.

Investigators then followed up with a 400-respondent quantitative survey done through an online tool. Participants, including nurse practitioners, physician assistants, registered nurses, and pharmacists, answered questions that took approximately 15 minutes to complete.

Evans says the results intrigued researchers and indeed proved how much the healthcare landscape has changed.

Influential individuals

Those who influenced prescribing decisions held non-MD positions, were a big part of the patient care journey and are often a patient’s last stop.

“Surprisingly, pharmacists, who we didn’t foresee as having the potential influence they probably do, emerged as a key segment because they’re at that retail kind of moment of truth,” Evans stated. “Affordability is an issue for a lot of Americans today.”

Lapolla says pharmacists are like referees or gatekeepers for the patient because “they’re the ones keeping their eyes on the cost” and trying to be an advocate for getting patients affordable care.

The pharmacist is usually one of the last contact points for a patient when receiving treatment in which a prescription is necessary.

Because pharmacists dwell in the world of medicine and see the costs associated with prescriptions daily, they are often much more informed about what a drug will cost compared to a medical doctor or provider’s office.

“We’ve been hearing from some clients that callbacks are a phenomenon for brands where they no longer have exclusivity,” Evans states.

“In talking to pharmacists, they say they want to get people their medications at the right price.”

Pharmacists are just one example of the non-MDs affecting prescription recommendations, albeit an important one.

Moreover, researchers found that face-to-face interactions with MDs are still very valuable.

Lapolla states one personnel member told him they are excited pharma reps are coming back because they provide valuable information and educational materials.

Pharma companies have done an excellent job adjusting their reps’ behaviours throughout the last decade by creating feedback loops, allowing representatives and companies to build more gratifying relationships with HCPs.

“I think that’s a credit to the industry, that they’re trying to make sure they put their best foot forward and are bringing value to their clients,” Lapolla states.

The researchers state their hypothesis was vetted, and now it’s essential to embrace these findings and think about how these influencers can contribute to business health and better patient outcomes.

Expanding pharma’s reach

Evans and Lapolla say pharma needs to recognise the increased scope of HCPs that arose from changes to the healthcare system and expand its reach to non-MD influencers.

“It’s probably good for [pharma companies] to provide information and an education to these other non-MD HCPs,” Evans states. “The reality is these folks are spending more time with patients, and they’re playing a role in the decision-making process.”

COVID has changed the landscape because more nurse practitioners and physician assistants now play a role in primary care.

“From a larger patient focus, we need to understand everybody who has a touchpoint to eventually get to better patient care,” Lapolla says.

“When all is said and done, if you’re going to focus on that patient and try to provide the best possible care for each individual patient, you have to understand the matrix of who’s dealing with them.”

Expanding pharma’s reach means expanding pharma’s points of contact, especially within marketing and its digital communication strategy, to include influential HCPs, such as pharmacists, nurse practitioners and physicians’ assistants.

“It’s about digging deeper. A lot of society is trying to cast a wider net and consider individuals or groups that haven’t traditionally been considered,” Lapolla states. “That aligns very well with including the direct care providers who are not physicians. We now realise the focus should be a little broader.”

About the interviewees

Cate Evans is the SVP group director, strategy at Havas Media Group. She has extensive experience working in various facets of the marketing industry including integrated media strategy, comms planning, media, marketing, brand strategy and PR. She has worked in media & communications planning for Johnson & Johnson brands including Listerine, Aveeno, Tylenol and Clean & Clear. She has continued to work in integrated strategy on the media side in both US and global roles for brands including ExxonMobil, Bacardi International, Invesco and now leads media strategy for Sanofi Pharmaceutical healthcare.

Nick Lapolla is research director at MedSurvey with over 15 years of experience in market research, all in healthcare. He designs and implements unique solutions and answers to challenging business questions, while using data to uncover what motivates human behaviour. He previously held market research positions at several companies under the umbrella of inVentiv Health (now Syneos Health). He has over a decade of primary and secondary pharmaceutical marketing research experience with an emphasis on quantitative and key opinion leader (KOL) research, as well as global experience across a broad range of therapeutic categories.

About the author

Jessica Hagen is a freelance life sciences and health writer and project manager who has worked with VR health companies, fiction/nonfiction authors, nonprofit and for-profit organisations and government entities.

 

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Looking Ahead In The Macro Market—Stock Market Preview For The Week Of June 27, 2022

A weekly stock market preview and the data that will impact the tape. Early Futures Open (6:24pm, June 26, 2022) – Stock Market Preview Weekend News…

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A weekly stock market preview and the data that will impact the tape.

Early Futures Open (6:24pm, June 26, 2022) – Stock Market Preview

Weekend News And Developments

Canadian Prime Minister drives action on food security, climate change and gender equality at Commonwealth Heads of Government Meeting.

Carvana (NYSE:CVNA) Sought to Disrupt Auto Sales. It Delivered Undriveable Cars—OpEd Barron’s

Honourable Jean-Yves Duclos, Minister of Health, and Member of Parliament for Bourassa, Emmanuel Dubourg, will make an important funding announcement supporting long-term care in Quebec; June 27, 11:15am.

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS), announced that GSK presented positive results from an interim analysis of the Phase 2b B-Clear clinical study of bepirovirsen (formerly IONIS-HBVRx), an investigational antisense medicine for the treatment of patients with chronic hepatitis B virus (CHB).

Madrigal Pharmaceuticals, Inc. announced data from multiple resmetirom abstracts presented at the European Association for the Study of the Liver’s International Liver Congress (EASL 2022), including a late-breaking presentation of data from the Phase 3 MAESTRO-NAFLD-1 study and three additional oral presentations from the resmetirom clinical development program.

Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) announced positive data evaluating the safety, tolerability, and immunogenicity of two Omicron-adapted COVID-19 vaccine candidates: one monovalent and the other bivalent, a combination of the Pfizer-BioNTech COVID-19 Vaccine and a vaccine candidate targeting the spike protein of the Omicron BA.1 variant of concern. 

President Joe Biden and Western allies opened a three-day summit in the Bavarian Alps on Sunday intent on keeping economic fallout from the war in Ukraine from fracturing the global coalition working to punish Russia’s aggression.

Saudi Exchange announces its intention to launch Single Stock Futures Contracts on the 4th of July 2022.

United States: The Biden admin alongside the G-7 announced that they will ban Russian gold imports to “further impose financial costs on Moscow for its invasion of Ukraine.”

What We’re Watching

U.S. Economic Calendar

TIME (ET)REPORTPERIODACTUALMEDIAN FORECASTPREVIOUS
Monday, June 27
8:30 AMDurable goods ordersMay0.20%0.50%
8:30 AMCore capital goods ordersMay0.80%
10:00 AMPending home sales indexMay-4.00%-3.90%
Tuesday, June 28
8:30 AMTrade in goods (advance)May-$105.9 billion
9:00 AMS&P Case-Shiller U.S. home price index (year-over-year)April20.60%
10:00 AMConsumer confidence indexJune101.1106.4
Wednesday, June 29
8:30 AMGross domestic product revision (SAAR)Q1-1.50%-1.50%
8:30 AMFinal domestic demand revision (SAAR)Q12.70%
8:30 AMGross domestic income revision (SAAR)Q12.10%
Thursday, June 30
8:30 AMPCE inflation (monthly)May0.20%
8:30 AMCore PCE inflation (monthly)May0.40%0.30%
8:30 AMPCE inflation (year-over-year)May6.30%
8:30 AMCore PCE inflation (year-over-year)May4.70%4.90%
8:30 AMReal disposable incomeMay0.00%
8:30 AMReal consumer spendingMay0.70%
8:30 AMNominal personal incomeMay0.50%0.40%
8:30 AMNominal consumer spendingMay0.40%0.90%
8:30 AMInitial jobless claimsJune 25227,000229,000
8:30 AMContinuing jobless claimsJune 181.32 million
9:45 AMChicago PMIJune60.3
Friday, July 1
9:45 AMS&P Global U.S. manufacturing PMI (final)June52.4
10:00 AMISM manufacturing indexJune54.90%56.10%
10:00 AMConstruction spendingJune0.40%0.20%

Meme Of The Week

Key Upcoming Earnings (US Markets)

DaySymbolCompanyEarnings Call TimeEPS Estimate
KPRXKiora Pharmaceuticals IncAfter Market Close-0.23
BYSIBeyondSpring IncTime Not Supplied-0.23
Monday, June 27KLDOKaleido Biosciences IncBefore Market Open-0.51
BMTXBm Technologies IncAfter Market Close0.08
CNTGCentogene NVBefore Market Open-0.53
CGRNCapstone Green Energy CorpAfter Market Close-0.28
CNXCConcentrix CorpAfter Market Close2.84
GPGreenPower Motor Company IncBefore Market Open-0.08
CTKYYCooTek (Cayman) IncBefore Market Open0.13
DLNGDynagas LNG Partners LPAfter Market Close0.17
TALTAL Education GroupBefore Market Open-0.05
EXPIeXp World Holdings IncTime Not Supplied0.01
JEFJefferies Financial Group IncAfter Market Close0.51
TCOMTrip.com Group LtdAfter Market Close-0.08
LVOLiveOne IncTime Not Supplied-0.13
NKENike IncTAS0.81
Tuesday, June 28AEMDAethlon Medical IncTAS-0.14
XAIRBeyond Air IncAfter Market Close-0.27
AVAVAeroVironment IncAfter Market Close0.39
FIZZNational Beverage CorpTime Not Supplied0.43
SJRShaw Communications IncTime Not Supplied0.3
SNXTD Synnex CorpBefore Market Open2.65
EPACEnerpac Tool Group CorpBefore Market Open0.28
PRGSProgress Software CorpAfter Market Close0.95
Wednesday, June 29CDMOAvid Bioservices IncAfter Market Close0.01
BSETBassett Furniture Industries IncTime Not Supplied0.45
BNEDBarnes & Noble Education IncBefore Market Open-0.17
BBBYBed Bath & Beyond IncBefore Market Open-1.37
CULPCulp IncAfter Market Close-0.35
CJREFCorus Entertainment IncBefore Market Open0.15
PDCOPatterson Companies IncBefore Market Open0.55
MKCMcCormick & Company IncBefore Market Open0.65
UNFUniFirst CorpBefore Market Open1.9
FCFranklin Covey CoAfter Market Close0.18
MSMMSC Industrial Direct Co IncBefore Market Open1.74
FTRPField Trip Health LtdAfter Market Close-0.18
SGHSMART Global Holdings Inc.After Market Close0.75
GISGeneral Mills IncBefore Market Open1.01
SCHNSchnitzer Steel Industries IncBefore Market Open2.3
NGNovaGold Resources IncAfter Market Close-0.03
PAYXPaychex IncBefore Market Open0.79
MLKNMillerKnoll IncAfter Market Close0.47
Thursday, June 30ACCDAccolade IncAfter Market Close-0.66
AYIAcuity Brands IncTAS2.95
WBAWalgreens Boots Alliance IncTAS0.92
WTERAlkaline Water Company IncBefore Market Open-0.1
STZConstellation Brands IncBefore Market Open2.52
LNNLindsay CorpBefore Market Open1.6
SMPLSimply Good Foods CoBefore Market Open0.35
TNPTsakos Energy Navigation LtdBefore Market Open-0.21
MUMicron Technology IncAfter Market Close2.44
Frdiay, July 1None

FDA Calendar

Spero Therapeutics, Inc. (Nasdaq: SPRO): The FDA is planning to hold an Advisory Committee meeting to discuss this application and has also set a Prescription Drug User Fee Act (PDUFA) target action date of June 27, 2022.

Short Interest Gainers

Carvana (CVNA) +33%: Short interest increased from 33.3% to just shy of the 35% mark—the highest level since December of 2020. Days to cover on Carvana rose from 1.3 to 1.6.

Chewy (CHWY) +32.96%: Short interest increased two percentage point increase to 28% to a two-month high. In the four-day period covered through Thursday, shares of Chewy are up 14.7%, though the stock remains down nearly 40% year-to-date.

Lemonade (LMND) +13.95% : Estimated short interest on the stock rose for the third consecutive week from 30.5% to 32.0%. Days to cover on Lemonade was also up nearly two points from 12.2 to 14.1- an all-times high.

Short Interest Decliners

Canoo (GOEV) -7.46%: Estimates short interest was down for the fourth consecutive week this week, slipping from 25.1% to 22.3%. Trading volume in the name has been particularly heavy this week with 5.5M-7.1M shares exchanging hands despite the absence of any meaningful news.

Citi Trends (CTRN) +3.58%: Estimated short interest peaked at an all-time high above 55% in mid-May, but has declined to just 30.1% since then as shorts cover on declining price action.

Tags: stock market preview, stock market preview June 27, 2022.

The post Looking Ahead In The Macro Market—Stock Market Preview For The Week Of June 27, 2022 appeared first on The Dales Report.

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40,000 National Guard Troops Face Unemployment As Vaccine Deadline Imminent

40,000 National Guard Troops Face Unemployment As Vaccine Deadline Imminent

Up to 40,000 Army National Guard troops – around 13% of the force…

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40,000 National Guard Troops Face Unemployment As Vaccine Deadline Imminent

Up to 40,000 Army National Guard troops - around 13% of the force - could be fired for not getting the mandated COVID-19 vaccine (which has limited efficacy against Omicron, doesn't stop transmission, has been linked to elevated heart problems, and has been mandated for a healthy demographic that rarely dies of the disease).

Michigan Army National Guard Sgt. Mark Abbott administers a COVID-19 vaccine

Guard soldiers have until Thursday to get the jab, according to the Associated Press, which notes that between 20% and 30% of Guard soldiers in six states remain unvaccinated.

"We’re going to give every soldier every opportunity to get vaccinated and continue their military career. Every soldier that is pending an exemption, we will continue to support them through their process," Lt. Gen. Jon Jensen, director of the Army National Guard, told AP. "We’re not giving up on anybody until the separation paperwork is signed and completed. There’s still time."

Last year, Defense Secretary Lloyd Austin ordered all service members to get the vaccine, with different branches maintaining different deadlines for the jab. The Army National Guard was given the maximum amount of time, largely because its roughly 330,000 soldiers are scattered throughout the country, including remote locations.

The Army Guard’s vaccine percentage is the lowest among the U.S. military — with all the active-duty Army, Navy, Air Force and Marine Corps at 97% or greater and the Air Guard at about 94%. The Army reported Friday that 90% of Army Reserve forces were partially or completely vaccinated.

The Pentagon has said that after June 30, Guard members won’t be paid by the federal government when they are activated on federal status, which includes their monthly drill weekends and their two-week annual training period. Guard troops mobilized on federal status and assigned to the southern border or on COVID-19 missions in various states also would have to be vaccinated or they would not be allowed to participate or be paid. -AP

Complicating matters is a rule that Guard soldiers deployed on state active duty may not require a vaccination, depending on state-level mandates. 

According to the report, at least seven governors have asked Austin to reconsider, or drop, the vaccine mandate for National Guard members - with some having filed or joined lawsuits to that end.

Austin, apparently following his own special brand of science, told them to pound sand, saying that Covid-19 "takes our service members out of the fight, temporarily or permanently, and jeopardizes our ability to meet mission requirements," adding that troops will either need to get vaccinated or lose their Guard status.

"When you’re looking at, 40,000 soldiers that potentially are in that unvaccinated category, absolutely there’s readiness implications on that and concerns associated with that," said Jenson, adding "That's a significant chunk." 

AP reports that around 85% of Army Guard soldiers are fully vaccinated, while 87% are at least partially vaccinated.

Tyler Durden Sun, 06/26/2022 - 18:00

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CDC Confirmed Post-Vaxx Death From Blood-Clotting Two Weeks Before Alerting Public: Emails

CDC Confirmed Post-Vaxx Death From Blood-Clotting Two Weeks Before Alerting Public: Emails

Authored by Zachary Stieber via The Epoch Times…

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CDC Confirmed Post-Vaxx Death From Blood-Clotting Two Weeks Before Alerting Public: Emails

Authored by Zachary Stieber via The Epoch Times (emphasis ours),

The Centers for Disease Control and Prevention (CDC) confirmed in late 2021 that a person died from blood clotting after receiving a COVID-19 vaccine that had been linked with an increased risk of blood clotting, but did not alert the public for two weeks, newly obtained emails show.

A general view of the Centers for Disease Control headquarters in Atlanta, Ga., on April 23, 2020. (Tami Chappell/AFP via Getty Images)

Dr. Tom Shimabukuro, a CDC official, told colleagues at the CDC and the Food and Drug Administration (FDA) on Dec. 2, 2021, “We have confirmed a 9th TTS death following Janssen vaccination,” according to emails obtained by The Epoch Times through a Freedom of Information Act request.

TTS refers to thrombosis with thrombocytopenia syndrome, a condition that features low platelet levels combined with blood clots.

Officials had recommended a nationwide pause on the administration of the vaccine, produced by Johnson & Johnson (J&J) subsidiary Janssen, in April 2021 after six women experienced TTS after J&J vaccination and three died. But they lifted the pause after determining the vaccine remained safe and effective.

The condition was not discussed much in the ensuing months, despite the CDC later reporting that five additional deaths occurred before Aug. 31, 2021. Shimabukuro gave a single update, in mid-October 2021, saying five total deaths had been reported.

That was until December 2021. Twelve days after Shimabukuro alerted colleagues of the ninth death, the FDA urged healthcare workers not to administer the vaccine to people with certain conditions because of the TTS risk. Two days after that, Dr. Isaac See, another CDC official, informed the public during a meeting that nine deaths had occurred post-vaccination.

It’s unclear when the CDC learned of the sixth, seventh, and eighth deaths.

The CDC takes reports made to the Vaccine Adverse Event Reporting System and attempts to confirm the reports, including post-vaccination deaths. A higher number of post-vaccination TTS deaths have been reported to the system than the number the CDC has verified.

One day after Shimabukuro confirmed the ninth death, his message was forwarded by Dr. Amanda Cohn, another CDC official, to CDC Director Dr. Rochelle Walensky.

“See below, information on a 9th completely tragic death from TTS,” Cohn wrote.

Many thanks for letting us know … any tragic case,” Walensky responded.

The emails were partially redacted; one was fully redacted.

Read more here...

Tyler Durden Sun, 06/26/2022 - 15:30

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