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Pharma Companies Finding It Difficult To Reach COVID-19 Supply Deal with EU

Exclusive: EU talks with Pfizer, Sanofi, J&J on COVID vaccines hit snags – sources

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This article was originally published by PharmaLive.

By Francesco Guarascio, Elvira Pollina BRUSSELS/MILAN (Reuters) – European efforts to secure potential COVID-19 vaccines from Pfizer (PFE.N), Sanofi (SASY.PA) and Johnson & Johnson (JNJ.N) are mired in wrangles over price, payment method and potential liability costs, three EU officials told Reuters. The bloc is in talks with at least six vaccine makers to acquire up front doses of potential shots against the novel coronavirus, officials told Reuters earlier in July, in a strategy meant to increase the chances of having COVID-19 vaccines for its population. Despite the urgency to seal deals amid a global race to secure the most promising shots, the EU is struggling to reach swift agreements, said the officials, who are involved in the talks, and declined to be named because the negotiations are confidential. The United States, meanwhile, has already inked two supply agreements with AstraZeneca (AZN.L) and Pfizer among other major funding deals. The EU’s negotiations with Johnson & Johnson are among the most advanced but have yet to conclude amid a back-and-forth over how to share liability costs if the potential vaccine showed unexpected side-effects, two of the officials told Reuters. Johnson & Johnson had no immediate comment. France’s Sanofi is negotiating to supply 300 million doses of the potential vaccine it is developing with British drugmaker GlaxoSmithKline Plc (GSK.L) to the EU and wants an immediate upfront payment for the entire stock, two officials said. But the EU wants to pay in tranches and delay some payments until the vaccine has passed large clinical trials, the officials said. This has caused “some hurdles,” one of the officials said. A spokesman for Sanofi declined to comment. A spokesman for the Commission, which is leading EU talks with drugmakers, declined to comment. Aside from the Pfizer, Sanofi and Johnson & Johnson discussions, the EU is also in talks with biotech companies Moderna (MRNA.O) and Germany’s CureVac, officials told Reuters earlier in July. Moderna and CureVac were not immediately available to comment. A deal with AstraZeneca (AZN.L) for its vaccine under development with Oxford University was struck by four large EU countries in June and is now about to be completed for the whole 27-nation bloc, officials said. One official said the EU was seeking to seal three or four advance purchase deals. “OVER BUDGET” The most complex talks appear to be with Pfizer and BioNtech which are developing a vaccine using an experimental technology known as messenger RNA, or mRNA, which has not been approved for commercial use by medical authorities. The two firms want the EU to pay them for 500 million doses only if their COVID-19 vaccine is authorised, one official told Reuters.

FILE PHOTO: European Union flags flutter outside the European Commission headquarters, ahead of an EU leaders summit at the European Council headquarters, in Brussels, Belgium July 16, 2020. REUTERS/Yves Herman

This might eliminate the EU’s risk of losing money should the shot prove unsuccessful. But the bloc fears that if it waits for the vaccine to be proved effective, the bill could be much higher and they risk going “over budget,” one of the officials said. In a further potential complication, some EU negotiators have raised doubts about mRNA, which is also used in the potential COVID vaccines developed by Moderna and CureVac. Pfizer and BioNtech are also discussing liability issues with EU negotiators, a fourth person familiar with the talks told Reuters. Pfizer and BioNTech declined to comment. The U.S. government last week agreed to pay nearly $2 billion to buy enough of the vaccine being developed by Pfizer and BioNTech to inoculate 50 million people, but with payments conditional on their vaccine being successful in large clinical trials. The price agreed under that deal of nearly $40 per course of treatment is considered too high by the EU, officials told Reuters last week. The EU is relying on about 2 billion euros ($2.3 billion) from an emergency fund to finance its possible deals with vaccine makers, which could be topped up with payments from EU governments. For instance, the agreement with AstraZeneca initially negotiated by Germany, France, Italy and the Netherlands cost the four countries 750 million euros for 300 million doses of the potential shot, an Italian official said, with an option to buy a further 100 million doses. That works out at 2.5 euros per dose. It is not clear whether under ongoing talks that money will now be provided by the EU emergency fund. ($1 = 0.8581 euros)

Additional reporting by Carl O’Donnell in New York, Matthias Blamont in Paris and Ludwig Burger in Frankfurt; Writing by Francesco Guarascio @fraguarascio; Editing by Josephine Mason and Carmel Crimmins

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Fighting the Surveillance State Begins with the Individual

It’s a well-known fact at this point that in the United States and most of the so-called free countries that there is a robust surveillance state in…

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It’s a well-known fact at this point that in the United States and most of the so-called free countries that there is a robust surveillance state in place, collecting data on the entire populace. This has been proven beyond a shadow of a doubt by people like Edward Snowden, a National Security Agency (NSA) whistleblower who exposed that the NSA was conducting mass surveillance on US citizens and the world as a whole. The NSA used applications like those from Prism Systems to piggyback on corporations and the data collection their users had agreed to in the terms of service. Google would scan all emails sent to a Gmail address to use for personalized advertising. The government then went to these companies and demanded the data, and this is what makes the surveillance state so interesting. Neo-Marxists like Shoshana Zuboff have dubbed this “surveillance capitalism.” In China, the mass surveillance is conducted at a loss. Setting up closed-circuit television cameras and hiring government workers to be a mandatory editorial staff for blogs and social media can get quite expensive. But if you parasitically leech off a profitable business practice it means that the surveillance state will turn a profit, which is a great asset and an even greater weakness for the system. You see, when that is what your surveillance state is predicated on you’ve effectively given your subjects an opt-out button. They stop using services that spy on them. There is software and online services that are called “open source,” which refers to software whose code is publicly available and can be viewed by anyone so that you can see exactly what that software does. The opposite of this, and what you’re likely already familiar with, is proprietary software. Open-source software generally markets itself as privacy respecting and doesn’t participate in data collection. Services like that can really undo the tricky situation we’ve found ourselves in. It’s a simple fact of life that when the government is given a power—whether that be to regulate, surveil, tax, or plunder—it is nigh impossible to wrestle it away from the state outside somehow disposing of the state entirely. This is why the issue of undoing mass surveillance is of the utmost importance. If the government has the power to spy on its populace, it will. There are people, like the creators of The Social Dilemma, who think that the solution to these privacy invasions isn’t less government but more government, arguing that data collection should be taxed to dissuade the practice or that regulation needs to be put into place to actively prevent abuses. This is silly to anyone who understands the effect regulations have and how the internet really works. You see, data collection is necessary. You can’t have email without some elements of data collection because it’s simply how the protocol functions. The issue is how that data is stored and used. A tax on data collection itself will simply become another cost of doing business. A large company like Google can afford to pay a tax. But a company like Proton Mail, a smaller, more privacy-respecting business, likely couldn’t. Proton Mail’s business model is based on paid subscriptions. If there were additional taxes imposed on them, it’s possible that they would not be able to afford the cost and would be forced out of the market. To reiterate, if one really cares about the destruction of the surveillance state, the first step is to personally make changes to how you interact with online services and to whom you choose to give your data.

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Stock Market Today: Stocks turn higher as Treasury yields retreat; big tech earnings up next

A pullback in Treasury yields has stocks moving higher Monday heading into a busy earnings week and a key 2-year bond auction later on Tuesday.

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Updated at 11:52 am EDT U.S. stocks turned higher Monday, heading into the busiest earnings week of the year on Wall Street, amid a pullback in Treasury bond yields that followed the first breach of 5% for 10-year notes since 2007. Investors, however, continue to track developments in Israel's war with Hamas, which launched its deadly attack from Gaza three weeks ago, as leaders around the region, and the wider world, work to contain the fighting and broker at least a form of cease-fire. Humanitarian aid is also making its way into Gaza, through the territory's border with Egypt, as officials continue to work for the release of more than 200 Israelis taken hostage by Hamas during the October 7 attack. Those diplomatic efforts eased some of the market's concern in overnight trading, but the lingering risk that regional adversaries such as Iran, or even Saudi Arabia, could be drawn into the conflict continues to blunt risk appetite. Still, the U.S. dollar index, which tracks the greenback against a basket of six global currencies and acts as the safe-haven benchmark in times of market turmoil, fell 0.37% in early New York trading 105.773, suggesting some modest moves into riskier assets. The Japanese yen, however, eased past the 150 mark in overnight dealing, a level that has some traders awaiting intervention from the Bank of Japan and which may have triggered small amounts of dollar sales and yen purchases. In the bond market, benchmark 10-year note yields breached the 5% mark in overnight trading, after briefly surpassing that level late last week for the first time since 2007, but were last seen trading at 4.867% ahead of $141 billion in 2-year, 5-year and 7-year note auctions later this week. Global oil prices were also lower, following two consecutive weekly gains that has take Brent crude, the global pricing benchmark, firmly past $90 a barrel amid supply disruption concerns tied to the middle east conflict. Brent contracts for December delivery were last seen $1.06 lower on the session at $91.07 per barrel while WTI futures contract for the same month fell $1.36 to $86.72 per barrel. Market volatility gauges were also active, with the CBOE Group's VIX index hitting a fresh seven-month high of $23.08 before easing to $20.18 later in the session. That level suggests traders are expecting ranges on the S&P 500 of around 1.26%, or 53 points, over the next month. A busy earnings week also indicates the likelihood of elevated trading volatility, with 158 S&P 500 companies reporting third quarter earnings over the next five days, including mega cap tech names such as Google parent Alphabet  (GOOGL) - Get Free Report, Microsoft  (MSFT) - Get Free Report, retail and cloud computing giant Amazon  (AMZN) - Get Free Report and Facebook owner Meta Platforms  (META) - Get Free Report. "It’s shaping up to be a big week for the market and it comes as the S&P 500 is testing a key level—the four-month low it set earlier this month," said Chris Larkin, managing director for trading and investing at E*TRADE from Morgan Stanley. "How the market responds to that test may hinge on sentiment, which often plays a larger-than-average role around this time of year," he added. "And right now, concerns about rising interest rates and geopolitical turmoil have the potential to exacerbate the market’s swings." Heading into the middle of the trading day on Wall Street, the S&P 500, which is down 8% from its early July peak, the highest of the year, was up 10 points, or 0.25%. The Dow Jones Industrial Average, which slumped into negative territory for the year last week, was marked 10 points lower while the Nasdaq, which fell 4.31% last week, was up 66 points, or 0.51%. In overseas markets, Europe's Stoxx 600 was marked 0.11% lower by the close of Frankfurt trading, with markets largely tracking U.S. stocks as well as the broader conflict in Israel. In Asia, a  slump in China stocks took the benchmark CSI 300 to a fresh 2019 low and pulled the region-wide MSCI ex-Japan 0.72% lower into the close of trading.
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iPhone Maker Foxconn Investigated By Chinese Authorities

Foxconn, the Taiwanese company that manufactures iPhones on behalf of Apple (AAPL), is being investigated by Chinese authorities, according to multiple…

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Foxconn, the Taiwanese company that manufactures iPhones on behalf of Apple (AAPL), is being investigated by Chinese authorities, according to multiple media reports. Foxconn’s business has been searched by Chinese authorities and China’s main tax authority has conducted inspections of Foxconn’s manufacturing operations in the Chinese provinces of Guangdong and Jiangsu. At the same time, China’s natural-resources department has begun onsite investigations into Foxconn’s land use in Henan and Hubei provinces within China. Foxconn has manufacturing facilities focused on Apple products in three of the Chinese provinces where authorities are carrying out searches. While headquartered in Taiwan, Foxconn has a huge manufacturing presence in China and is a large employer in the nation of 1.4 billion people. The investigations suggest that China is ramping up pressure on the company as Foxconn considers major investments in India, and as presidential elections approach in Taiwan. Foxconn founder Terry Gou said in August of this year that he intends to run for the Taiwanese presidency. He has resigned from the company’s board of directors but continues to hold a 12.5% stake in the company. Gou is currently in fourth place in the polls ahead of the election that is scheduled to be held in January 2024. The potential impact on Apple and its iPhone manufacturing comes amid rising political tensions between politicians in Washington, D.C. and Beijing. Apple’s stock has risen 16% over the last 12 months and currently trades at $172.88 U.S. per share.  

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