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Growing Number Of Experts Call On US Govt To Recognize Natural Immunity

Growing Number Of Experts Call On US Govt To Recognize Natural Immunity

Authored by Zachary Stieber via The Epoch Times,

A growing number…

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Growing Number Of Experts Call On US Govt To Recognize Natural Immunity

Authored by Zachary Stieber via The Epoch Times,

A growing number of experts are urging the U.S. government to formally recognize natural immunity, or the protection given by recovering from COVID-19.

More experts are arguing that the Centers for Disease Control and Prevention’s (CDC) recommended vaccination schedule should feature fewer doses—or none at all—for people who have contracted COVID-19 and survived.

“Natural infection should count as two doses,” Dr. Paul Offit, professor of pediatrics at the Children’s Hospital of Philadelphia, and an adviser to the Food and Drug Administration on vaccines, told The Epoch Times.

Offit and two former FDA officials stated in a recent op-ed that “requiring people who have been infected to get three shots is overkill at best—a waste of valuable doses—and an unnecessary risk at worst (given that vaccines have side effects, albeit rare ones).”

Under current CDC guidance, all Americans 12 and older are advised to get three doses of the Moderna or Pfizer COVID-19 vaccines. The CDC defines fully vaccinated as people who get two shots of the Moderna or Pfizer COVID-19 vaccines, or the single-shot Johnson & Johnson jab.

The CDC’s guidance isn’t binding but is cited by companies and jurisdictions when imposing vaccine mandates. Many mandates force workers or residents to get fully vaccinated; others require a booster on top of the primary series because of waning protection. Few have exemptions for natural immunity.

Eric Topol, founder and director of the Scripps Research Translational Institute, wrote in a separate op-ed that the increasing number of studies showing how strong and long-lasting natural immunity is should prompt the CDC to redefine fully vaccinated in two ways: People who have gotten a primary series and not been infected should need a third dose, while those with prior infection should only need one shot.

Recent research on the matter includes a study funded by Johnson & Johnson and the U.S. government that found that previous infection alone provided 90 percent protection against moderate to severe COVID-19—the vaccine only provided 56 percent protection—and a paper backed by the CDC that found natural immunity was more protective than vaccination against the Delta variant of SARS-CoV-2.

Some experts, such as Offit, push for what’s known as hybrid immunity. They point to papers that suggest that people who have been infected and go on to get a single vaccine dose are better protected than those with prior infection who remain unvaccinated, including a Cleveland Clinic study published earlier in February.

Dr. David Boulware, a professor of medicine at the University of Minnesota, agrees.

A transmission electron micrograph shows SARS-CoV-2 virus particles isolated from a patient. (NIAID)

Boulware said he worries that not everybody who contracts COVID-19 will generate an immune response. He helped with a study published in 2021 that had participants self-collect serologic samples. The findings indicate that people with more COVID-19 symptoms were more likely to show evidence of prior infection.

“For persons with prior documented COVID-19, they should receive at least one follow-up vaccine at three to six months after initial infection. For those with prior infection, two sequential vaccines in rapid sequence of 0, 21, or 28 days do virtually nothing immunologically, other than generate side effects. At present (based on current rules), I would recommend all those with prior infection to have a vaccine at three months after initial infection and then again after six months from initial infection,” Boulware told The Epoch Times in an email.

Top U.S. health officials such as CDC Director Dr. Rochelle Walensky have acknowledged that natural immunity occurs but have repeatedly urged people to get vaccinated, even if they recover from COVID-19, with a full vaccination schedule.

Offit says he was among four people who were asked to share their views on natural immunity in 2021 with Walensky and other officials, including Dr. Anthony Fauci, the longtime head of the National Institute of Allergy and Infectious Diseases (NIAID) and the chief medical adviser to President Joe Biden. The virtual meeting, which took place after Surgeon General Vivek Murthy was confirmed by the Senate and before Dr. Francis Collins stepped down as head of the National Institutes of Health (NIH), didn’t lead to a shift in government guidance.

“I think it’s because the opinions were sort of generally diverse, so there wasn’t a clear, unified message that came out of that,” Offit told The Epoch Times.

One possible issue is how people could prove they’ve been infected and recovered, with suggestions including serologic tests.

The CDC, the NIH, NIAID, Murthy, Walensky, Fauci, and Collins didn’t respond to requests for comment. The Epoch Times has filed Freedom of Information Act requests for details on the meeting.

Other experts say the protection people with natural immunity enjoy is so strong that they may not or definitely don’t need any vaccine doses.

Dr. Robert Malone, who helped create the messenger RNA technology that the Pfizer and Moderna vaccines are built on, pointed to research that suggests that people with natural immunity have a greater risk of suffering adverse events after getting vaccinated as well as a collection of studies on protection from natural immunity.

“Over 140 papers demonstrate that—superiority of natural immunity,” Malone told The Epoch Times. “And furthermore, if you jab somebody after they have natural immunity, their risk of adverse events goes up.”

One recent study from Italian researchers found that people who recovered from COVID-19 had a low risk of reinfection and a very low risk of severe or deadly COVID-19. They said the risk-benefit of vaccine doses for the population should be “carefully evaluated.”

“From the point of view of the individual who recovered from a previous infection, vaccination will provide a very limited benefit, as his/her risk of a severe or lethal disease is extremely low, especially if she/he is young,” Dr. Lamberto Manzoli, one of the authors, told The Epoch Times in an email.

On the other hand, vaccinating the naturally immune “may still provide some benefit, because approximately 1 percent of these subjects may have a reinfection and therefore transmit the disease,” he said. “Clearly, their impact on the overall pandemic is difficult to quantify, and it is likely to be very scarce, but if we want to take a very conservative approach, vaccination may still provide some benefit. Importantly, we have to use the word ‘may’ because, as I mentioned in the manuscript, an in-depth evaluation of the risk-benefit should be made for these subjects.”

Tyler Durden Fri, 02/25/2022 - 19:00

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Low Iron Levels In Blood Could Trigger Long COVID: Study

Low Iron Levels In Blood Could Trigger Long COVID: Study

Authored by Amie Dahnke via The Epoch Times (emphasis ours),

People with inadequate…

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Low Iron Levels In Blood Could Trigger Long COVID: Study

Authored by Amie Dahnke via The Epoch Times (emphasis ours),

People with inadequate iron levels in their blood due to a COVID-19 infection could be at greater risk of long COVID.

(Shutterstock)

A new study indicates that problems with iron levels in the bloodstream likely trigger chronic inflammation and other conditions associated with the post-COVID phenomenon. The findings, published on March 1 in Nature Immunology, could offer new ways to treat or prevent the condition.

Long COVID Patients Have Low Iron Levels

Researchers at the University of Cambridge pinpointed low iron as a potential link to long-COVID symptoms thanks to a study they initiated shortly after the start of the pandemic. They recruited people who tested positive for the virus to provide blood samples for analysis over a year, which allowed the researchers to look for post-infection changes in the blood. The researchers looked at 214 samples and found that 45 percent of patients reported symptoms of long COVID that lasted between three and 10 months.

In analyzing the blood samples, the research team noticed that people experiencing long COVID had low iron levels, contributing to anemia and low red blood cell production, just two weeks after they were diagnosed with COVID-19. This was true for patients regardless of age, sex, or the initial severity of their infection.

According to one of the study co-authors, the removal of iron from the bloodstream is a natural process and defense mechanism of the body.

But it can jeopardize a person’s recovery.

When the body has an infection, it responds by removing iron from the bloodstream. This protects us from potentially lethal bacteria that capture the iron in the bloodstream and grow rapidly. It’s an evolutionary response that redistributes iron in the body, and the blood plasma becomes an iron desert,” University of Oxford professor Hal Drakesmith said in a press release. “However, if this goes on for a long time, there is less iron for red blood cells, so oxygen is transported less efficiently affecting metabolism and energy production, and for white blood cells, which need iron to work properly. The protective mechanism ends up becoming a problem.”

The research team believes that consistently low iron levels could explain why individuals with long COVID continue to experience fatigue and difficulty exercising. As such, the researchers suggested iron supplementation to help regulate and prevent the often debilitating symptoms associated with long COVID.

It isn’t necessarily the case that individuals don’t have enough iron in their body, it’s just that it’s trapped in the wrong place,” Aimee Hanson, a postdoctoral researcher at the University of Cambridge who worked on the study, said in the press release. “What we need is a way to remobilize the iron and pull it back into the bloodstream, where it becomes more useful to the red blood cells.”

The research team pointed out that iron supplementation isn’t always straightforward. Achieving the right level of iron varies from person to person. Too much iron can cause stomach issues, ranging from constipation, nausea, and abdominal pain to gastritis and gastric lesions.

1 in 5 Still Affected by Long COVID

COVID-19 has affected nearly 40 percent of Americans, with one in five of those still suffering from symptoms of long COVID, according to the U.S. Centers for Disease Control and Prevention (CDC). Long COVID is marked by health issues that continue at least four weeks after an individual was initially diagnosed with COVID-19. Symptoms can last for days, weeks, months, or years and may include fatigue, cough or chest pain, headache, brain fog, depression or anxiety, digestive issues, and joint or muscle pain.

Tyler Durden Sat, 03/09/2024 - 12:50

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Walmart joins Costco in sharing key pricing news

The massive retailers have both shared information that some retailers keep very close to the vest.

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As we head toward a presidential election, the presumed candidates for both parties will look for issues that rally undecided voters. 

The economy will be a key issue, with Democrats pointing to job creation and lowering prices while Republicans will cite the layoffs at Big Tech companies, high housing prices, and of course, sticky inflation.

The covid pandemic created a perfect storm for inflation and higher prices. It became harder to get many items because people getting sick slowed down, or even stopped, production at some factories.

Related: Popular mall retailer shuts down abruptly after bankruptcy filing

It was also a period where demand increased while shipping, trucking and delivery systems were all strained or thrown out of whack. The combination led to product shortages and higher prices.

You might have gone to the grocery store and not been able to buy your favorite paper towel brand or find toilet paper at all. That happened partly because of the supply chain and partly due to increased demand, but at the end of the day, it led to higher prices, which some consumers blamed on President Joe Biden's administration.

Biden, of course, was blamed for the price increases, but as inflation has dropped and grocery prices have fallen, few companies have been up front about it. That's probably not a political choice in most cases. Instead, some companies have chosen to lower prices more slowly than they raised them.

However, two major retailers, Walmart (WMT) and Costco, have been very honest about inflation. Walmart Chief Executive Doug McMillon's most recent comments validate what Biden's administration has been saying about the state of the economy. And they contrast with the economic picture being painted by Republicans who support their presumptive nominee, Donald Trump.

Walmart has seen inflation drop in many key areas.

Image source: Joe Raedle/Getty Images

Walmart sees lower prices

McMillon does not talk about lower prices to make a political statement. He's communicating with customers and potential customers through the analysts who cover the company's quarterly-earnings calls.

During Walmart's fiscal-fourth-quarter-earnings call, McMillon was clear that prices are going down.

"I'm excited about the omnichannel net promoter score trends the team is driving. Across countries, we continue to see a customer that's resilient but looking for value. As always, we're working hard to deliver that for them, including through our rollbacks on food pricing in Walmart U.S. Those were up significantly in Q4 versus last year, following a big increase in Q3," he said.

He was specific about where the chain has seen prices go down.

"Our general merchandise prices are lower than a year ago and even two years ago in some categories, which means our customers are finding value in areas like apparel and hard lines," he said. "In food, prices are lower than a year ago in places like eggs, apples, and deli snacks, but higher in other places like asparagus and blackberries."

McMillon said that in other areas prices were still up but have been falling.

"Dry grocery and consumables categories like paper goods and cleaning supplies are up mid-single digits versus last year and high teens versus two years ago. Private-brand penetration is up in many of the countries where we operate, including the United States," he said.

Costco sees almost no inflation impact

McMillon avoided the word inflation in his comments. Costco  (COST)  Chief Financial Officer Richard Galanti, who steps down on March 15, has been very transparent on the topic.

The CFO commented on inflation during his company's fiscal-first-quarter-earnings call.

"Most recently, in the last fourth-quarter discussion, we had estimated that year-over-year inflation was in the 1% to 2% range. Our estimate for the quarter just ended, that inflation was in the 0% to 1% range," he said.

Galanti made clear that inflation (and even deflation) varied by category.

"A bigger deflation in some big and bulky items like furniture sets due to lower freight costs year over year, as well as on things like domestics, bulky lower-priced items, again, where the freight cost is significant. Some deflationary items were as much as 20% to 30% and, again, mostly freight-related," he added.

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Walmart has really good news for shoppers (and Joe Biden)

The giant retailer joins Costco in making a statement that has political overtones, even if that’s not the intent.

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As we head toward a presidential election, the presumed candidates for both parties will look for issues that rally undecided voters. 

The economy will be a key issue, with Democrats pointing to job creation and lowering prices while Republicans will cite the layoffs at Big Tech companies, high housing prices, and of course, sticky inflation.

The covid pandemic created a perfect storm for inflation and higher prices. It became harder to get many items because people getting sick slowed down, or even stopped, production at some factories.

Related: Popular mall retailer shuts down abruptly after bankruptcy filing

It was also a period where demand increased while shipping, trucking and delivery systems were all strained or thrown out of whack. The combination led to product shortages and higher prices.

You might have gone to the grocery store and not been able to buy your favorite paper towel brand or find toilet paper at all. That happened partly because of the supply chain and partly due to increased demand, but at the end of the day, it led to higher prices, which some consumers blamed on President Joe Biden's administration.

Biden, of course, was blamed for the price increases, but as inflation has dropped and grocery prices have fallen, few companies have been up front about it. That's probably not a political choice in most cases. Instead, some companies have chosen to lower prices more slowly than they raised them.

However, two major retailers, Walmart (WMT) and Costco, have been very honest about inflation. Walmart Chief Executive Doug McMillon's most recent comments validate what Biden's administration has been saying about the state of the economy. And they contrast with the economic picture being painted by Republicans who support their presumptive nominee, Donald Trump.

Walmart has seen inflation drop in many key areas.

Image source: Joe Raedle/Getty Images

Walmart sees lower prices

McMillon does not talk about lower prices to make a political statement. He's communicating with customers and potential customers through the analysts who cover the company's quarterly-earnings calls.

During Walmart's fiscal-fourth-quarter-earnings call, McMillon was clear that prices are going down.

"I'm excited about the omnichannel net promoter score trends the team is driving. Across countries, we continue to see a customer that's resilient but looking for value. As always, we're working hard to deliver that for them, including through our rollbacks on food pricing in Walmart U.S. Those were up significantly in Q4 versus last year, following a big increase in Q3," he said.

He was specific about where the chain has seen prices go down.

"Our general merchandise prices are lower than a year ago and even two years ago in some categories, which means our customers are finding value in areas like apparel and hard lines," he said. "In food, prices are lower than a year ago in places like eggs, apples, and deli snacks, but higher in other places like asparagus and blackberries."

McMillon said that in other areas prices were still up but have been falling.

"Dry grocery and consumables categories like paper goods and cleaning supplies are up mid-single digits versus last year and high teens versus two years ago. Private-brand penetration is up in many of the countries where we operate, including the United States," he said.

Costco sees almost no inflation impact

McMillon avoided the word inflation in his comments. Costco  (COST)  Chief Financial Officer Richard Galanti, who steps down on March 15, has been very transparent on the topic.

The CFO commented on inflation during his company's fiscal-first-quarter-earnings call.

"Most recently, in the last fourth-quarter discussion, we had estimated that year-over-year inflation was in the 1% to 2% range. Our estimate for the quarter just ended, that inflation was in the 0% to 1% range," he said.

Galanti made clear that inflation (and even deflation) varied by category.

"A bigger deflation in some big and bulky items like furniture sets due to lower freight costs year over year, as well as on things like domestics, bulky lower-priced items, again, where the freight cost is significant. Some deflationary items were as much as 20% to 30% and, again, mostly freight-related," he added.

Read More

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