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Futures Swing In Slowmotion Overnight Rollercoaster

Futures Swing In Slowmotion Overnight Rollercoaster



Futures Swing In Slowmotion Overnight Rollercoaster Tyler Durden Mon, 06/22/2020 - 08:08

Welcome to a new week, and a new rollercoaster in illiquid overnight futures trading, which saw spoos start off sharply lower on fresh coronavirus concerns after new cases in California rose by a record (4,515) and Florida infections up 3.7% from a day earlier, compared with an average increase of 3.5% in the previous seven days, while the German R-naught surged almost 3x to 2.88 in three days. As a reminder, on Friday stocks slumped late in the day after Apple said that it will again close almost a dozen stores in the US because of a recent rise in coronavirus infections in the South and West, denting the optimism that the US recovery is in full swing.

However, sentiment reversed sharply around 9pm ET when China reported that Beijing saw only 9 new cases suggesting that the latest breakout in the capital had been contained while South Korea saw the smallest daily increase in about a month, prompting renewed optimism that everything is once again under control. Futures then continued their ascent into the early European open, when Eminis rose as high as 3,097 before once again hitting the brakes and reversing modestly lower. Despite the rise in virus cases in Germany and the U.S. states of Florida, California and Texas.

Sentiment was also lifted by the same old news, that there’s growing speculation that politicians will be unwilling to put cities back on lockdown because of the economic toll. Historical stimulus programs by the major central banks are also supporting the sentiment.

European shares also opened lower as much as 1.1% but then quickly staged a sharp rally and nudged into positive territory as a jump in Germany’s coronavirus reproduction rate over the weekend was seen as unlikely to trigger a massive second wave or new lockdowns. Germany’s coronavirus reproduction rate jumped to 2.88 on Sunday from 1.06 on Friday, health authorities said. The spike in infections was mainly related to local outbreaks including in North Rhine-Westphalia.

“I regard the German R statistic as a bit of a red herring or more of a statistical quirk,” said Chris Bailey, Raymond James European strategist. "Coronavirus at-the-margin remains an overhang but the opening up of Europe still looks on much more solid foundations than the US/Americas."

Meanwhile Germany's mega-fraud WireCard shed another 50% of its market cap after the company admitted $2.1 billion in cash will never be found. The plunge assured that CEO Braun is facing financial ruins as he no longer has enough shares to cover his €150MM margin loan.

Asian stocks were little changed, with communications rising and industrials falling, after rising in the last session. Markets in the region were mixed, with Thailand's SET and South Korea's Kospi Index falling, and India's S&P BSE Sensex Index and Singapore's Straits Times Index rising. The Topix declined 0.2%, with Olympic and Land Co falling the most. The Shanghai Composite Index was little changed, with Ningxia Xinri Hengli Steel Wire advancing and Guangdong Songyang declining the most.

Investors are also wary of developments in Hong Kong after details of a new security law for the territory showed Beijing will  have overarching powers on its enforcement. China’s top legislative body, the National People’s Congress Standing Committee, will meet on June 28, and the Global Times reported it was likely to enact the Hong Kong security law by July 1.

Hong Kong's Hang Seng .HSI fell 0.5%, underperforming regional markets.

Torn between record stimulus and growing fears of a second wave of infections, global stocks have been moving sideways in recent weeks after rising more than 40% from March lows on hopes the worst of the pandemic was over.

“Markets have climbed back ... with stocks proving the doubter wrong yet again as a world of stimulus trumps the reality of economic and health struggles,” said Joshua Mahony, senior market analyst at IG.

In rates, the 10Y TSY yield dropped to 0.685%, trading around its 50DMA, and back in sideways trading range after false breakout beginning of June. The yield on Germany’s 30-year government debt fell below zero for the first time since May. Crude oil hovered below $40 a barrel in New York. Bunds bull flattened, breaching Friday’s highs and outperforming Treasuries by ~1bp. Gilts bull steepen slightly in a subdued reaction to comments from BOE’s Bailey.

In FX, the U.S. dollar meanwhile slipped from two-and-a-half-week highs as risk appetite remained alive in a world awash with cheap money after credit rating agency Moody’s warned that the stimulus measures will leave advanced economies with much higher debt than they accumulated during the last financial crisis. “Government debt/GDP ratios will rise by around 19 percentage points, nearly twice as much as in 2009 during the GFC ... the rise in debt burdens will be more immediate and pervasive, reflecting the acuteness and breadth of the shock posed by the coronavirus.” Moody’s said.

The pound rose for the first time in five days against the dollar after Governor Andrew Bailey indicated that the Bank of England would reduce the size of its balance sheet before considering interest-rate increases. The euro also headed for the first gain since June 15. New Zealand’s dollar and the Swedish krona led G-10 currency gains. U.S. stock futures dictated the market’s mood after a record increase in California’s new virus cases was followed by news that China was containing a resurgence of infections, prompting a rally.

As central banks continued their unprecedented liquidity firehose, gold finally appeared reach to breach $1,750, nearing a seven-year high.

Elsewhere in commodities, oil prices steadied on tighter supplies from major producers, but concerns that the rising coronavirus cases could curb demand checked gains. Brent rose 0.2% to $42.25 a barrel, while WTI fell slightly to $39.65 a barrel.

Market Snapshot

  • S&P 500 futures up 0.7% to 3,082.25
  • STOXX Europe 600 down 0.2% to 364.83
  • MXAP down 0.09% to 159.14
  • MXAPJ down 0.06% to 513.47
  • Nikkei down 0.2% to 22,437.27
  • Topix down 0.2% to 1,579.09
  • Hang Seng Index down 0.5% to 24,511.34
  • Shanghai Composite down 0.08% to 2,965.27
  • Sensex up 1.2% to 35,159.56
  • Australia S&P/ASX 200 up 0.03% to 5,944.54
  • Kospi down 0.7% to 2,126.73
  • German 10Y yield fell 1.7 bps to -0.432%
  • Euro up 0.3% to $1.1209
  • Brent Futures up 0.02% to $42.20/bbl
  • Italian 10Y yield fell 2.2 bps to 1.229%
  • Spanish 10Y yield fell 1.9 bps to 0.474%
  • Brent Futures up 0.02% to $42.20/bbl
  • Gold spot up 0.2% to $1,747.44
  • U.S. Dollar Index down 0.2% to 97.41

Top Overnight News from Bloomberg

  • Germany’s coronavirus infection rate rose for a third day, lifted by local outbreaks including in the region of North Rhine-Westphalia, where more than 1,300 people working at a slaughterhouse tested positive.
  • Beijing reported only nine new infections, a sign that a recent outbreak is under control. China blocked poultry from a Tyson Foods plant where many workers tested positive
  • The European Central Bank’s most determined attempt yet to confront the German legal headache bedeviling its quantitative easing policy may emerge as soon as this week.
  • Bank of England Governor Andrew Bailey signaled a major shift in the central bank’s strategy for removing emergency stimulus, stressing the need to reduce the institution’s balance sheet before hiking interest rates.

Asian equity markets began the week cautiously as sentiment was clouded by reports of increasing COVID-19 infections rates globally in which the World Health Organization reported a record daily increase of 183k cases, while new cases in the US topped the 7-day average and Germany’s reproduction rate surged to 2.88 from 1.79. This initially pressured US equity futures at the open and also weighed on ASX 200 (U/C) and Nikkei 225 (-0.2%), although US index futures have since fully recovered and Asia-Pac bourses also retraced their early declines with outperformance seen in commodity-related sectors, in particular Australia’s gold miners after the precious metal resumed its rally and broke above the USD 1750/oz level. Hang Seng (-0.5%) and Shanghai Comp. (-0.1%) were mixed with price action rangebound after the PBoC maintained its 1-year and 5-year Loan Prime Rates at 3.85% and 4.65% respectively as expected, while it also conducted a CNY 120bln net liquidity injection which was welcomed by mainland bourses. Furthermore, there were reports that China is planning to step up purchases of US farm goods following recent discussions and that President Trump deferred sanctions on Chinese officials related to Uighur minorities as it may impact the US-China trade deal, although Hong Kong lagged after the release of the draft Hong Kong National Security Law which the Standing Committee of the NPC is speculated to enact when it meets on June 28th-30th. Finally, 10yr JGB traded subdued as the intraday recovery in Japanese stocks weighed on bond prices but with downside also cushioned by the BoJ’s presence in the market for over JPY 1tln of JGBs with 1yr-10yr maturities and with the Japan Securities Dealers Association noting regional banks bought a record amount of ultra-long JGBs last month.

Top Asian News

  • Hong Kong Central Office Vacancies Reach 12-Year High: JLL
  • Japan Industry Group May Penalize Banks Breaking Debt Sale Rules
  • Virus- Drug Nod Spurs Record Rally in India’s Glenmark Pharma
  • The Most Popular U.S. Bond Market Trade Has Now Gone Global

Europe kicked the week off on the back-foot but have since nursed a bulk of its losses [Euro Stoxx 50 -0.4%] as initial downside stemmed from second wave woes amid record daily increases recorded by the WHO, Germany’s R-number jumping amid cluster outbreaks and with the US cases rising above its key 7-day level. Nonetheless, stock markets continued on its upwards trajectory since the cash open despite light fundamental news-flow. Note, the EU-China summit is underway but with expectations low. Sources noted there will be no joint communique between the sides this year – but, the meeting with Germany could prove to be interesting as the country will be taking the baton of rotating EU presidency in H2 2020; note, Germany has previously signalled a tougher EU line towards China. Nonetheless, bourses regain earlier lost ground alongside sectors – now mixed following an all-negative open – but still fail to indicate a clear risk tone. The sectorial breakdown also provides little clarity on this front as Oil & Gas, Travel & Leisure and telecoms remain the laggards. In terms of individual movers, Wirecard (-36%) shares continue to suffer after the group announced the missing EUR 1.9bln likely never existed, whilst it withdrew its prelim FY19 and Q1-2020 results. Separately, former CEO Braun - who was the largest individual shareholder - is reportedly unloading a large amount of his 7% stake in the Co. Elsewhere, Lufthansa (-6%) shares are weighed on after its CEO stated that the EUR 9bln state-backed aid is at risk of not passing the upcoming shareholder vote as only around 40% of shareholders have registered to vote at the EGM thus far vs. required 2/3 majority for it to pass. On the flip side, BT (+1.9%) remains supported by reports that the Saudi Public Investment Fund is said to have been acquiring a stake in the Co. through open-market purchases over the last few weeks, according to sources.

Top European News

  • Lufthansa Braces for Portentous Week With Future on the Line
  • Turkish Stocks Erase 2020 Losses After Wave of Local Buying
  • Halkbank, Involved in U.S. Case, Jumps After Berman Resigns

In FX, the Greenback is weaker across the G10 board with only the Yen underperforming, and then only marginally vs the scale of recovery gains forged by other majors. Further increases in coronavirus infections and fatalities appear to be weighing on the Buck even though the US is far from alone in terms of suffering fresh outbreaks. Indeed, the KCDC is reportedly classifying the situation in South Korea as a 2nd wave as the global tally hit the highest level so far for a single day, according to the WHO and Germany’s R value rebounds to 2.88. However, the DXY has slipped back below 97.500 to a 97.287 low from last Friday’s 97.727 high ahead of May’s national activity index, existing home sales and a late speech from Fed’s Kashkari.

  • AUD/NZD/GBP/SEK/EUR - The Aussie is back within striking distance of 0.6900 vs its US counterpart and not too unsettled by comments from RBA Governor Lowe overnight reiterating that rates are likely to remain at current levels for years, as he also seemed unfazed by the Aud’s present valuation. Meanwhile, the Kiwi has reclaimed 0.6400+ status ahead of the RBNZ policy meeting with markets all but ruling out any chance of a change in rates, but Sterling’s comeback from the low 1.2300 area towards 1.2435 is somewhat less easy to reconcile and may have more to do with Eur/Gbp flows/direction as the cross pulls back from 0.9065 to test bids said to be sitting at 0.9025. Note also, 1.85 bn option expiries at 0.9060 may be capping the cross ahead of the NY cut after Sterling shrugged off an improvement in CBI trends. Elsewhere, the Swedish Crown is also perky against the single currency and perhaps drawing some traction from the latest Riksbank business survey revealing stabilisation in May and June, though the Euro has clawed back gains vs the Dollar from circa 1.1168 to hover between decent expiry interest at 1.1200-05 (1.9 bn) and 1.1245-50 (1.24 bn) ahead of flash Eurozone consumer confidence and ECB speeches via de Guindos and Lane.
  • CAD/CHF/NOK - Also on a firmer footing to at least start the new week, with the Loonie nearer the top of a 1.3560-1.3630 range vs its US peer awaiting comments from BoC Governor Macklem, the Franc back above 0.9500 in wake of latest weekly Swiss bank sight deposits showing a dip in both domestic and total balances and the Norwegian Krona consolidating post-Norges Bank advances either side of 10.8000 against the Euro.
  • JPY/XAU - As noted above, the Yen is bucking the broad trend, but still keeping its head over 107.00 and Gold has lost some steam after surging above Usd 1750/oz and stalling ahead of the next major bullish technical target around Usd 1765 from May 18.

In commodities, WTI and Brent August contracts remain choppy and reside within a tight range, albeit the benchmarkes have nursed opening losses of around 1%, which originally emanated from COVID-19 second wave woes as the WHO reported a record daily increase of 183k cases, while new cases in the US topped the 7-day average and Germany’s R-rate spiked to 2.88 from 1.79. Meanwhile, Nigeria and Angola will be presenting their respective over-compliance plans today after failing to do so last week – with a presser expected following a review of the strategy – albeit, this has not been confirmed. Meanwhile, a new study shows that US shale companies could be forced into writing down at least USD 300bln of assets in Q2 as producers account for the oil price collapse earlier this year on balance sheets, which will be based on an oil price around USD 35/bbl according to the FT. WTI August fluctuates on either side of USD 40/bbl (vs. 39/bbl low) whilst its Brent counterpart tested resistance at USD 42.50 (vs. 41.58/bbl low) earlier in the session. Elsewhere, spot gold has given up some recent gains amid the recovery in stocks, but nonetheless currently remains underpinned by a weaker USD – with the yellow metal trading on either side of USD 1750/oz early-doors before printing a marginal new session low at USD 1741.90/oz. Copper prices are supported by the softer Buck and continues to trend higher amid support from draws in LME and China inventories. In terms of bank commentary, Citi sees gold prices at an average of USD 1702/oz this year and USD 1761/oz next year, whilst the bank forecasts copper at USD 5654/t in 2020 and 5850/t in 2021.

US Event Calendar

  • 8:30am: Chicago Fed Nat Activity Index, prior -16.7
  • 10am: Existing Home Sales, est. 4.09m, prior 4.33m; Existing Home Sales MoM, est. -5.59%, prior -17.8%

DB's Jim Reid concludes the overnight wrap

Hard to believe we’re now going to have to deal with the nights slowly getting darker again here in the northern hemisphere. We spent the longest day yesterday at the beach and I think we’ll be discovering sand in various places across the house, car and bodies for the next week. It’s a horrendously messy thing to do, especially when the showers were closed for social distancing reasons. It is amazing what the bracing sea air does though as bed time went without incident last night, which is a rarity. They were all shattered.

It was amazing how busy the beach was but people generally practiced social distancing unless they were just deliberately keeping out the way of my horrors. It’s a strange period where life is getting slowly back to some kind of normality, but with major constraints and with everyone waiting to see what happens next. Indeed the virus spread continues to create a lot of uncertainty in markets. For example, does it matter that the troublesome US states are continuing to see case numbers increase or does it provide some good news that economies can stay open as cases rumble on? It’s possible that with more knowledge on the virus, the vulnerable are now being better protected which will dramatically reduce the fatalities if successful.

Even in countries that are perceived to have had a good response to the crisis are having issues. Last week we highlighted the reports out of Germany of a meat factory closing due to a rash of infections. Over the weekend, the Robert Koch Institute estimated that the effective reproduction factor of the virus was now 1.79 in the country after being 1.06 on Friday, and below 1.0 earlier in June. Yesterday there were over 600 new cases in the country, with the 7 day average of new cases over 500 for the first time in 5 weeks. It will be interesting to see how they deal with this small uptick that has shades of a second wave. China is also seeing a mini second wave with the country now having averaged around 40 new cases per day for the last week, after seeing low single-digit new cases per day all through May and early June. Beijing has closed schools and asked those who can to work from home when possible. In a positive sign, Beijing reported only 9 new cases overnight.

Elsewhere Brazil is still engulfed in their first wave passing 1 million total cases over the weekend, and registering 54,711 new cases on Friday, the most new cases in one day for any country in the world. They did have a small reporting backlog though. Nevertheless cases have risen by 3.3% per day over the last 7 days, in line with the 7 day period prior at 3.4%. The other virus hotspot is the US. After registering multiple days with daily case growth under 1.0% in the early part of June, cases have been rising at 1.5% per day on average over the last week, higher than the 1.2% average for the period previous. The majority of these cases are in large Southern states like Texas, Florida, and Arizona, but California continues to have similar problems. All four states currently have a 7-day average of new cases higher than the period prior, implying that the virus spread is accelerating and no longer even flat.

Using rtlive’s estimates, whose underlying methodology was updated over the weekend, 24 of the 50 US states now have effective transmission rates over 1.0. Of the main focus states, California has been trending higher for the last month and after falling back below 1.0, it is now at 1.05. Florida is at 1.39 and Texas at 1.16.

So plenty of worrying news on the virus at a global level but there are still signs that technicals in the market look supportive. Doing my weekend reading of DB research it was interesting to read our equity strategist Binky Chadha’s latest view where he suggested positioning in US equities has dipped again to the 5th percentile. He suggested that such low positioning is historically associated with strong performance of the market 1 week and 1 month forward. See here for more. A reminder that when Binky discussed the low positioning a few weeks ago one of the main justifications for that during a big rally was the emergence of new retail investors into the market with institutional investors remaining relatively on the sidelines.

A quick check on markets this morning now where broadly speaking most Asian bourses have pared a weak open. The Nikkei (+0.31%), Shanghai Comp (+0.28%) and ASX (+0.47%) are now showing modest gains while the Kospi is flat and the Hang Seng down -0.32%, likely not helped by news over the weekend that China has proposed a national security law that would allow the Beijing to override Hong Kong’s independent legal system. Elsewhere, futures on the S&P 500 are trading up +0.65% after erasing losses at the open of c. -1%.

In other weekend news, a Bloomberg story has argued that a change in the composition of Germany's Constitutional Court has the potential to be less confrontational towards the ECB. Astrid Wallrabenstein, seen as more EU friendly, will replace Andreas Vosskuhle, president of the court whose term has expired and made the May 5 ruling on the ECB bond purchases while, Stephan Harbarth, a conservative lawmaker from 2009-2018, will become the new president. German daily Frankfurter Allgemeine Sonntagszeitung has already reported Wallrabenstein saying that it could be in the interest of the court to take an easier stand if the “demands are being taken seriously” and the actions taken by politicians, the German central bank and ECB “go into the right direction.” This comes on the back of Friday’s news that the ECB is preparing papers on proportionality of the PSPP to satisfy the GCC.

Staying with Europe, Italian PM Conte has indicated that his government would likely seek a wider budget gap as the government will focus on infrastructure projects including high-speed railways and may approve a value-added tax cut to stem the coronavirus’s impact. He said, “We will probably need to intervene for a further widening of the budget gap because the resources are not enough to cope with the impact of a horrible year both economically and socially,” while, adding that the government will present its reform plan in September. The reform plan is in response to lobby for the country’s share of a proposed EUR 750bn recovery fund.

The main highlight this week is likely to be the flash PMIs for June tomorrow, with manufacturing, services and composite PMIs coming out from around the world. Back in May, the PMIs rebounded from April’s rock-bottom prints. For example, the Euro Area composite PMI rose to 31.9 from 13.6, while in the US the composite PMI recovered to 37.0 from 27.0. For June the range of expectations across Europe/US are generally in the 40s with U.K. at the lower end and the US manufacturing possibly scraping to just over 50. Given these are diffusion indices and simply reflect whether conditions are getting better or worse then surely at some point soon these numbers are going to massively spike up regardless of the actual level of growth.

There are various other data releases but it’s not a big week for data. See the day by day calendar at the end for the full slate. Note that the IMF’s latest economic forecasts are released this Wednesday. In a website blogpost last week, their Chief Economist Gita Gopinath said that the update “is likely to show negative growth rates even worse than previously estimated.”

Looking back at last week now, Global equities finished higher but there feels like there is a bit more two way tension in asset markets now. Nevertheless, the significant amount of liquidity in the financial system and a steady drip of improving data outweighed concerns of a rise of covid-19 cases in China and Germany (albeit from low levels) as well as in the largest US states. The S&P 500 rose +1.86% (-0.56% Friday as Apple reversed a decision to reopen some stores in high case states). The index is now down -4.12% YTD. The last two weeks have seen growth stocks go back to outperforming in the US, with the tech-focused Nasdaq finishing this past week up +3.73% (+0.03% Friday). European equities also outperformed the S&P, with the Stoxx 600 rallying +3.22% (+0.56% Friday) over the five days. The rally was widespread with the DAX (+3.19%), FTSE MIB (+3.87%), FTSE 100 (+3.07%), and CAC (+2.90%) all gaining on the week. Asian indices also rose but to a lesser degree. The Nikkei rose +0.78% over the week (+0.55% Friday) while the CSI 300 was up +2.39% (+1.34% Friday), and the Kospi rose +0.42% (+0.37% Friday). The CSI 300 joined the NASDAQ as one of the few equity indices in the world that is up on the year, closing Friday +0.05% YTD.

Oil prices rallied for a 7th week out of the last 8 as OPEC+ gave reassurances on output cuts on Thursday. Expectations for demand also continues to slowly improve. WTI futures rose +9.62% (+2.34% Friday) to $39.75/barrel and Brent crude rose +8.93% on the week (+1.64% Friday) to $42.19/barrel. With risk assets rising and sentiment staying generally constructive, HY credit spreads on both sides of the Atlantic tightened on the week. European HY cash spreads were -15bps tighter on the week (+2bps Friday), while US HY cash spreads were -26bps tighter (+1bp Friday). Euro IG and US IG cash spreads were -3bps (+1bp Friday) and -12bps (-1bp Friday) tighter, respectively.

Peripheral debt tightened, with Spanish 10yr yields -12.6bps tighter to German bunds over the 5 days, while Italian BTPs were -11.4bps tighter, and Portuguese bonds tightened -8.5bps. Core sovereign bonds were little changed on the week as US 10yr Treasury yields fell -1.0bps (-1.5bps Friday) to finish at 0.694%, while 10yr Bund yields rose +2.4bps over the course of the week (-0.8bps Friday) to -0.42%.

The main highlight from last Friday was the European Council meeting where leaders were cautious, but still constructive on a Recovery Fund agreement. German Chancellor Merkel mentioned that an agreement had been reached on the mixture of grants and loans, while Austrian Chancellor Kurz said that grants would be possible, with conditionality. It feels like compromise is slowly building even if we’re not yet there. On the data front, the main two headlines were out of the UK. Public finance data for May showed the government’s debt-to-GDP ratio rose above 100% for the first time since 1963. Retail sales in the UK rose +12.0% MoM during May, well above the expected rise of 6.3% and recovering from last month’s revised -18.0% fall.

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Spread & Containment

How bonds work and why everyone is talking about them right now: a finance expert explains

Investor confidence in the UK is at a low, and the bond market has reacted dramatically.



The Bank of England is buying bonds again. Just as it was about to start selling the debt it had accumulated as part of its last effort to support the economy during the COVID-19 pandemic, the central bank has been forced to announce a new scheme to shore up investor confidence.

The bank’s £65 billion short-term spree aims to address the slump in bond prices caused by investors rushing to sell after the government’s recent mini-budget. This led to a surge in bond yields that hiked borrowing costs for the government and spread to pensions, housing and the general economy. So far, it has had a limited initial impact on the markets.

We asked an expert in finance to explain what’s going on in bond markets.

What is a bond and what is the difference between bond prices and yields?

A bond is essentially a tradeable IOU. It’s a loan that investors make to issuers such as companies or governments (UK government bonds are often called gilts). A bond has a price at which it can be sold and a yield, which is an annual amount the investor receives for holding the bond, a bit like interest on a savings account, and is expressed as a percentage of the current price.

When the price of a bond falls, it signals less demand for the bond because fewer investors want to own it. At the same time, the yield rises, which represents a higher cost of borrowing for companies or governments that issued the bond because this is what they have to pay to investors.

In the days since the government’s mini-budget, yields on 10-year Treasury bonds – which are issued by the UK government – increased from approximately 3.5% to 4.52% – the highest since the 2007-2008 global financial crisis. The expectation of continued increases prompted the recent intervention by the Bank of England.

UK government 10-year bond yields

United Kingdom 10-year bond yield. / Tradingview

What causes bond yields to move?

To understand this, it is important to bear in mind that, while people often talk about the interest rate, there are actually a number of rates. This includes the rate at which the central bank lends to commercial banks (the base rate), the rate that banks lend to each other (the interbank rate), the rate that the government borrows at (Treasury yields) and the rate at which households and firms borrow (commercial loans and mortgages).

When the Bank of England changes the base rate, this cascades through all these rates. As such, the Bank of England carefully considers the state of the economy – that is, growth and inflation – when deciding on the base rate.

When an economy is growing, interest rates and bond yields tend to rise. The occurs for several reasons. Investors sell bonds to buy riskier assets with better returns. Firms and households also look to borrow more money in a growing economy, for example, to invest in new machinery or to move home. More demand for borrowing means lenders can charge higher interest on their loans.

Higher inflation often accompanies economic growth because of the increase in demand for goods and services. This tightens supply and causes prices to rise (including wages for labour). The Bank of England, which is mandated by the government to try to keep inflation as close to 2% as possible, will respond to higher inflation by raising base rates, which, as noted, feeds through to the different rates.

Investors will often anticipate the increase in base rates and look to act before it goes up by selling Treasury bonds and buying alternative, higher return, assets. This causes bond yields to rise further. As a result, the Treasury bond yield is often seen as a predictor of future Bank of England base rate changes.

So, if yields are rising, does this mean that investors are expecting future economic growth in the UK?

No, not at the moment. When the government raises money by issuing bonds, it does so over a range of time periods (called maturities), from one day to 30 years. When an economy is expected to grow, the yield on longer-term bonds will be higher than the yield on shorter-term bonds.

This relationship between yields across different maturities is referred to as the term structure or yield curve. An upward sloping yield curve implies a growing economy. At the moment, the UK yield curve is flat, or even downward-sloping across some maturities. My research shows that a falling yield curve is a good predictor of a coming recession.

Yield curve for UK government bonds

Line graph showing downward-sloping yield curve for UK gilts
UK gilts 40-year yield curve. *The curve on the day of the previous MPC meeting is provided as reference point. Bloomberg Finance L.P., Tradeweb and Bank of England calculations

It’s important to remember that these different yields act as a benchmark for commercial lending rates of equivalent lengths. The approximate jump to 4.5% in 2-year and 5-year yields has been reflected in mortgage rates, which is why some lenders have pulled available mortgage deals recently while they reassess the lending rates charged to households.

Read more: Is the UK in a recession? How central banks decide and why it's so hard to call it

But if the UK economy is not expected to perform well, why have bond yields been rising after the chancellor’s mini-budget announcement?

The rising bond yields we are seeing relate to an additional factor: the amount of government debt. The mini-budget introduced tax cuts and increased spending and investors know the government will need to increase borrowing to meet these commitments. Some estimates put potential government borrowing at £190 billion due to this plan.

An increase in the amount a homeowner borrows versus the value of their home (called the loan-to-value) causes the mortgage rate charged to the borrower to rise. Similarly, an increase in the amount of bonds that the government will be looking to sell (the amount it wants to borrow) will push down the price of existing bonds, increasing yields. More importantly, more debt without growth raises the risk level of the UK economy.

Anticipating this, investors triggered a large-scale bond sell-off after the government’s mini-budget announcement. This contributed to the fall in the value of the pound as investors selling UK Treasury bonds bought US bonds instead, essentially swapping pounds for dollars.

So will the Bank of England’s plan work?

The intervention will have a short-term positive impact, which started as soon as it was announced. But the bank is really only buying time. Any ultimate success depends on the government restoring investor confidence in its economic plans.

Unfortunately, rising yields and borrowing costs for the UK economy is the price we are now paying for the government’s recent fiscal announcement.

David McMillan does not work for, consult, own shares in or receive funding from any company or organisation that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

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Spread & Containment

Zika Vaccine Targeting Nonstructural Viral Proteins Found Effective in Mice

UCLA scientists report positive preclinical results on the safety and efficacy of an RNA vaccine (ZVAX) against the mosquito borne Zika virus that severely…



Positive preclinical results on the safety and efficacy of an RNA vaccine (ZVAX) against the mosquito-borne Zika virus that severely compromises brain development in children of infected mothers, were published in the journal Microbiology Spectrum on September 28, 2022 “Replication-Deficient Zika Vector-Based Vaccine Provides Maternal and Fetal Protection in Mouse Model.” The investigators tested the vaccine in pregnant mice and report the vaccine prevents systemic Zika infection in both mothers and developing fetuses.

“The ongoing COVID-19 pandemic has shown us the power of a strong pandemic preparedness plan and clear communication about prevention methods—all culminating in the rapid rollout of safe and reliable vaccines,” said senior author of the study, Vaithilingaraja Arumugaswami, DVM, PhD, an associate professor of molecular and medical pharmacology at the University of California, Los Angeles (UCLA). “Our research is a crucial first step in developing an effective vaccination program that could curb the spread of Zika virus and prevent large-scale spread from occurring.”

Vaithilingaraja Arumugaswami, DVM, PhD, an associate professor of molecular and medical pharmacology at the University of California, Los Angeles (UCLA) is a co-senior author of the study.

Engineering the vaccine

The experimental vaccine is composed of RNA that encodes nonstructural proteins found within the pathogen that trigger an immune response against the virus.

Arumugaswami said, “Engineering the vaccine involved deleting the part of the Zika genome that codes for the viral shell. This modification both stimulates an immunogenic reaction and prevents the virus from replicating and spreading from cell to cell.”

Eliminating structural proteins that mutate rapidly to escape the immune system also ensures that the vaccine trains the recipient’s immune system to recognize viral elements that are less likely to alter. The researchers packaged the replication deficient Zika vaccine particles in human producer cells and verified antigen expression in vitro.

Nikhil Chakravarty, a co-author of the study and student at the UCLA Fielding School of Public Health
oversaw data analysis and writing of the manuscript.

“We deleted not just the gene responsible for encoding the capsid, but also those encoding the viral envelope and membrane. This vaccine is replication-deficient—it cannot spread among cells,” said co-author of the study, Nikhil Chakravarty, a master’s student at the UCLA Fielding School of Public Health.

Chakravarty clarified, “The deletion itself does not lead to stimulation of immune response but it makes this vaccine safer by rendering it replication deficient. The nonstructural proteins encoded by the RNA packaged in the vaccine stimulate more of a T-cell immune response that can specifically recognize Zika-infected cells and prevent viral replication and the spread of infection.”

The team showed increased effector T cell numbers in vaccinated versus unvaccinated mouse models. Using mass cytometry, the researchers showed high levels of splenic CD81 positive T cells and effector memory T cell responses and low levels of proinflammatory cell responses in vaccinated animals, suggesting that endogenous expression of the nonstructural viral proteins by the vaccine induced cellular immunity. There were no changes in antibody mediated humoral immunity in the vaccinated mice.

Co-author Gustavo Garcia, Jr., oversaw and conducted much of the experimentation reported in the study.

“We saw complete protective immunity against Zika virus in both pregnant and nonpregnant animals, speaking to the strength and utility of our vaccine candidate,” said Chakravarty. “This supports the deployment of this vaccine in pregnant mothers—the population, perhaps, most at need—upon further clinical evaluation. This would help mitigate some of the socioeconomic fallout from a potential Zika outbreak, as well as prevent neurological and developmental deficits in Zika-exposed children.”

The investigators administered the RNA vaccine using a prime-boost regimen where an initial dose was followed up by a booster dose. To estimate the durability of the vaccine, the researchers monitored the mice for a month-and-a-half, which is equivalent to approximately seven years in humans.

Chakravarty said, “Since the vaccine is geared toward stimulating T-cell response, we anticipate it will induce longer-lasting immunity than if it were just stimulating antibody immune response.”

Pandemic preparedness

The global Zika outbreak in 2016, led to efforts in developing effective therapies and vaccines against the virus. However, no vaccines or treatments have been approved for Zika virus yet.

“Other Zika vaccine candidates mainly focused on using structural proteins as immunogens, which preferably stimulates antibody response. Our candidate is unique in that it targets nonstructural proteins, which are more conserved across viral variants, and stimulate T-cell-mediated immunity,” said Chakravarty.

Epidemiological studies have shown that the Zika virus spreads approximately every seven years. Moreover, the habitats of Zika-spreading mosquitoes are increasing due to climate change, increasing the likelihood of human exposure to the virus.

“Given that RNA viruses—the category to which both Zika and the SARS family of viruses belong—are highly prone to evolving and mutating rapidly, there will likely be more outbreaks in the near future,” said Arumugaswami.

Kouki Morizono, MD, PhD, an associate professor of medicine at UCLA is a co-senior author of this study.

“It’s only a matter of time before we start seeing the virus spread again,” said Kouki Morizono, MD, PhD, an associate professor of medicine at UCLA and co-senior author of this study.

Before the vaccine candidate can be tested in humans, the researchers will be test it non-human primate models.

The post Zika Vaccine Targeting Nonstructural Viral Proteins Found Effective in Mice appeared first on GEN - Genetic Engineering and Biotechnology News.

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Butter, garage doors and SUVs: Why shortages remain common 2½ years into the pandemic

The bullwhip effect describes small changes in demand that become amplified as they move down the supply chain, resulting in shortages. The pandemic put…




Consumers have been seeing empty shelves throughout the pandemic. Diana Haronis/Moment

Shortages of basic goods still plague the U.S. economy – 2½ years after the pandemic’s onset turned global supply chains upside down.

Want a new car? You may have to wait as long as six months, depending on the model you order. Looking for a spicy condiment? Supplies of Sriracha hot sauce have been running dangerously low. And if you feed your cat or dog dry pet food, expect empty shelves or elevated prices.

These aren’t isolated products. Baby formula, wine and spirits, lawn chairs, garage doors, butter, cream cheese, breakfast cereal and many more items have also been facing shortages in the U.S. during 2022 – and popcorn and tomatoes are expected to be in short supply soon.

In fact, global supply chains have been under the most strain in at least a quarter-century, and have been pretty much ever since the COVID-19 pandemic began.

I have been immersed in supply chain management for over 35 years, both as a manager and consultant in the private sector and as an adjunct professor at Colorado State University - Global Campus.

While each product experiencing a shortage has its own story as to what went wrong, at the root of most is a concept people in my field call the “bullwhip effect.”

What is the ‘bullwhip effect’?

The term bullwhip effect was coined in 1961 by MIT computer scientist Jay Forrester in his seminal book “Industrial Dynamics.” It describes what happens when fluctuations in demand reverberate and amplify throughout the supply chain, leading to worsening problems and shortages.

Imagine the physics of cracking a whip. It starts with a small flick of the wrist, but the whip’s wave patterns grow exponentially in a chain reaction, leading to the tip, a snap – and a sharp pain for anyone on the receiving end.

The same thing can happen in supply chains when orders for a product from a retailer, say, go up or down by some amount and that gets amplified by wholesalers, distributors and raw material suppliers.

The onset of the COVID-19 pandemic, which led to lengthy lockdowns, massive unemployment and a whole host of other effects that messed up global supply chains, essentially supercharged the bullwhip’s snap.

How the bullwhip effect works.

Cars and chips

The supply of autos is one such example.

New as well as used vehicles have been in short supply throughout the pandemic, at times forcing consumers to wait as long as a year for the most popular models.

In early 2020, when the pandemic put most Americans in lockdown, carmakers began to anticipate a fall in demand, so they significantly scaled back production. This sent a signal to suppliers, especially of computer chips, that they would need to find different buyers for their products.

Computer chips aren’t one size fits all; they are designed differently depending on their end use. So chipmakers began making fewer chips intended for use in cars and trucks and more for computers and smart refrigerators.

So when demand for vehicles suddenly returned in early 2021, carmakers were unable to secure enough chips to ramp up production. Production last year was down about 13% from 2019 levels. Since then, chipmakers have began to produce more car-specific chips, and Congress even passed a law to beef up U.S. manufacturing of semiconductors. Some carmakers, such as Ford and General Motors, have decided to sell incomplete cars, without chips and the special features they power like touchscreens, to relieve delays.

But shortages remain. You could chalk this up to poor planning, but it’s also the bullwhip effect in action.

The bullwhip is everywhere

And this is a problem for a heck of a lot of goods and parts, especially if they, like semiconductors, come from Asia.

In fact, pretty much everything Americans get from Asia – about 40% of all U.S. imports – could be affected by the bullwhip effect.

Most of this stuff travels to the U.S. by container ships, the cheapest means of transportation. That means goods must typically spend a week or longer traversing the Pacific Ocean.

The bullwhip effect comes in when a disruption in the information flow from customer to supplier happens.

For example, let’s say a customer sees that an order of lawn chairs has not been delivered by the expected date, perhaps because of a minor transportation delay. So the customer complains to the retailer, which in turn orders more from the manufacturer. Manufacturers see orders increase and pass the orders on to the suppliers with a little added, just in case.

What started out as a delay in transportation now has become a major increase in orders all down the supply chain. Now the retailer gets delivery of all the products it overordered and reduces the next order to the factory, which reduces its order to suppliers, and so on.

Now try to visualize the bullwhip of orders going up and down at the suppliers’ end.

The pandemic caused all kinds of transportation disruptions – whether due to a lack of workers, problems at a port or something else – most of which triggered the bullwhip effect.

The end isn’t nigh

When will these problems end? The answer will likely disappoint you.

As the world continues to become more interconnected, a minor problem can become larger if information is not available. Even with the right information at the right time, life happens. A storm might cause a ship carrying new cars from Europe to be lost at sea. Having only a few sources of baby formula causes a shortage when a safety issue shuts down the largest producer. Russia invades Ukraine, and 10% of the world’s grain is held hostage.

The early effects of the pandemic in 2020 led to a sharp drop in demand, which rippled through supply chains and decreased production. A strong U.S. economy and consumers flush with coronavirus cash led to a surge in demand in 2021, and the system had a hard time catching up. Now the impact of soaring inflation and a looming recession will reverse that effect, leading to a glut of stuff and a drop in orders. And the cycle will repeat.

As best as I can tell, these disruptions will take many years to recover from. And as recent inflation reduces demand for goods, and consumers begin cutting back, the bullwhip will again work its way through the supply chain – and you’ll see more shortages as it does.

Michael Okrent does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

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