Connect with us

Spread & Containment

“Dead” Virus Cells Frequently Trigger “False Positives” In Most Common COVID Test, New Study Finds

"Dead" Virus Cells Frequently Trigger "False Positives" In Most Common COVID Test, New Study Finds

Published

on

"Dead" Virus Cells Frequently Trigger "False Positives" In Most Common COVID Test, New Study Finds Tyler Durden Sat, 09/05/2020 - 21:20

In the past, our reports raising questions about the accuracy of COVID-19 tests have been met with accusations of 'fearmongering' and spreading 'misinformation'. 

But not today.

That's because new research from the University of Oxford’s Center for Evidence-Based Medicine and the University of the West of England has found that the swab-based technique used for most COVID-19 testing is at risk of returning "false positives" since copies of the virus's RNA detected by the tests might simply be dead, inactive material from a weeks-old infection. Although patients infected with COVID-19 are typically only infectious for a week or less, tests can be triggered by virus genetic material left over from a weeks-old infection.

The team's research involved analyzing 25 studies on the widely used polymerase chain reaction test. PCR tests use material collected with a swab - the most common type of test around the world, and especially in the US - then utilize a "genetic photocopying" technique that allows scientists to magnify the small sample of genetic material collected, which they can then analyze for signs of viral RNA.

What the researchers here have effectively found is that these PCR tests just aren't sensitive enough to distinguish if the viral material is active and infectious, or dead and inert.

For those who desire a more comprehensive understanding of how these tests work, the chart below can be helpful.

Professor Carl Heneghan, one of the authors of the study, said there was a risk that a surge in testing across the UK was increasing the risk of this sample contamination occurring and it may explain why the number of Covid-19 cases is rising but the number of deaths is static.

"Evidence is mounting that a good proportion of ‘new’ mild cases and people re-testing positives after quarantine or discharge from hospital are not infectious, but are simply clearing harmless virus particles which their immune system has efficiently dealt with," he told the Spectator.

Professor Heneghan added that international scrutiny might be required to avoid "the dangers of isolating non-infectious people or whole communities."

Read More

Continue Reading

Spread & Containment

The Great Reset In Action: Ending Freedom Of The Press, Speech, & Expression

The Great Reset In Action: Ending Freedom Of The Press, Speech, & Expression

Authored by Birsen Filip via The Mises Institute,

Governments,…

Published

on

The Great Reset In Action: Ending Freedom Of The Press, Speech, & Expression

Authored by Birsen Filip via The Mises Institute,

Governments, corporations, and elites have always been fearful of the power of a free press, because it is capable of exposing their lies, destroying their carefully crafted images, and undermining their authority. In recent years, alternative journalism has been growing and more people are relying on social media platforms as sources of news and information. In response, the corporate state, digital conglomerates, and the mainstream media have been increasingly supportive of the silencing and censoring of alternative media outlets and voices that challenge the official narrative on most issues.

At the recent World Economic Forum meeting in Davos, Switzerland, "Australian eSafety commissioner" Julie Inman Grant stated that "freedom of speech is not the same thing as a free for all," and that "we are going to need a recalibration of a whole range of human rights that are playing out online—from freedom of speech … to be free from online violence." Meanwhile, the Canadian government is seeking to restrict independent media and the freedom of expression via the implementation of Bill C-11, which would allow it to regulate all online audiovisual platforms on the internet, including content on Spotify, Tik Tok, YouTube, and podcast clients.

Similarly, the UK is seeking to introduce an Online Safety Bill, the US "paused" the establishment of a Disinformation Governance Board following backlash, and the European Union approved its own Digital Services Act, all of which aim to limit the freedom of speech. Attempts by elites and politicians to silence dissenters and critical thinkers is not something new. In fact, history is full of examples of "the persecution of men of science, the burning of scientific books, and the systematic eradication of the intelligentsia of the subjected people."

However, these current efforts to curtail freedom of speech and press by supposedly liberal governments are still somewhat ironic, given that even "the most intolerant of churches, the Roman Catholic Church, even at the canonization of a saint, admits, and listens patiently to, a 'devil's advocate.' The holiest of men, it appears, cannot be admitted to posthumous honors, until all that the devil could say against him is known and weighed."

The corporate state, digital conglomerates, and the mainstream media want to ensure that they have the exclusive authority to dictate people's opinions, wants, and choices through their sophisticated propaganda techniques. To do so, they have even resorted to transforming falsehoods into truth. In fact, the word truth has already had its original meaning altered, as those who speak the truth on certain subjects are now regularly accused of spreading hate speech, misinformation, and disinformation.

Presently, truth is no "longer something to be found, with the individual conscience as the sole arbiter of whether in any particular instance the evidence (or the standing of those proclaiming it) warrants a belief; it becomes something to be laid down by authority, something which has to be believed in the interest of the unity of the organized effort, and which may have to be altered as the exigencies of this organised effort require it."

However, modifying the definition of truth comes with the potential for great peril, as truth-seeking often contributes to human progress in that it leads to discoveries that ultimately benefit society at large. It should be noted that truth is by no means the only word whose meaning has been changed recently in order for it to serve as an instrument of propaganda; others include freedomjusticelawrightequalitydiversitywomanpandemicvaccine, etc. This is highly concerning, because such attempts at the "perversion of language, the change of meaning of the words by which the ideals" of the ruling class are expressed is a consistent feature of totalitarian regimes.

As a number of liberal-democratic governments increasingly move toward totalitarianism, they want people to forget that there is "the greatest difference between presuming an opinion to be true, because, with every opportunity for contesting it, it has not been refuted, and assuming its truth for the purpose of not permitting its refutation." According to them, "public criticism or even expressions of doubt must be suppressed because they tend to weaken public support."

In fact, they believe that all views and opinions that might cast doubt or create hesitation need to be restricted in all disciplines and on all platforms. This is because "the disinterested search for truth cannot be allowed" when "the vindication of the official views becomes the sole object" of the ruling class. In other words, the control of information is practiced and the uniformity of views is enforced in all fields under totalitarian rule.

The suppression of freedom of the press, speech, expression, and thought means that current and future generations will be "deprived of the opportunity of exchanging error for truth: if wrong, they lose, what is almost as great a benefit, the clearer perception and livelier impression of truth, produced by its collision with error." They are also at risk of becoming ignorant of the fact that the only way in which a person can know "the whole of a subject" is by "hearing what can be said about it by persons of every variety of opinion, and studying all modes in which it can be looked at by every character of mind." That is to say, current and future generations will be unaware that "the steady habit of correcting and completing" one's own "opinion by collating it with those of others, so far from causing doubt and hesitation in carrying it into practice, is the only stable foundation for a just reliance on it."

At present, it is likely that the masses do not regard freedom of the press, speech, expression, and thought as being particularly important, because "the great majority are rarely capable of thinking independently, that on most questions they accept views which they find ready-made, and that they will be equally content if born or coaxed into one set of beliefs or another." Nevertheless, no one should have the power and authority to "select those to whom" freedom of thought, enlightenment and expression is to be "reserved."

In fact, John Stuart Mill went so far as to claim that "if all mankind minus one, were of one opinion, and only one person were of the contrary opinion, mankind would be no more justified in silencing that one person, than he, if he had the power, would be justified in silencing mankind." He further added that silencing the expression of an opinion is essentially an act of "robbing the human race," which applies to both current and future generations. Even though the suppressors can deny the truth to people at a particular point in time, "history shows that every age having held many opinions which subsequent ages have deemed not only false but absurd; and it is as certain that many opinions, now general, will be rejected by future ages, as it is that many, once general, are rejected by the present."

If current efforts to suppress freedom of the press, speech, expression, and thought succeed, then the search for truth will eventually be abandoned and totalitarian authorities will decide what "doctrines ought to be taught and published." There will be no limits to who can be silenced, as the control of opinions will be extended to all people in all fields. Accordingly, contemporary authoritarian policy makers need to be reminded about the crucial importance of freedom of speech, expression, and thought, which the US Supreme Court recognized in the 1957 case Sweezy v. New Hampshire when it ruled that

to impose any strait jacket upon the intellectual leaders in our colleges and universities would imperil the future of our Nation. No field of education is so thoroughly comprehended by man that new discoveries cannot yet be made…. Teachers and students must always remain free to inquire, to study and to evaluate, to gain new maturity and understanding; otherwise, our civilization will stagnate and die…. Our form of government is built on the premise that every citizen shall have the right to engage in political expression and association. This right was enshrined in the First Amendment of the Bill of Rights. Exercise of these basic freedoms in America has traditionally been through the media of political associations…. History has amply proved the virtue of political activity by minority, dissident groups, who innumerable times have been in the vanguard of democratic thought and whose programs were ultimately accepted. Mere unorthodoxy or dissent from the prevailing mores is not to be condemned. The absence of such voices would be a symptom of grave illness in our society.

Tyler Durden Thu, 06/30/2022 - 23:50

Read More

Continue Reading

Government

New Hampshire Governor Vetoes Ivermectin Bill

New Hampshire Governor Vetoes Ivermectin Bill

Authored by Alice Giordano via The Epoch Times (emphasis ours),

New Hampshire’s Republican…

Published

on

New Hampshire Governor Vetoes Ivermectin Bill

Authored by Alice Giordano via The Epoch Times (emphasis ours),

New Hampshire’s Republican Gov. Chris Sununu vetoed a bill that would have made Ivermectin available without a prescription.

Ivermectin tablets packaged for human use. (Natasha Holt/The Epoch Times)

The Republican governor vetoed the bill on June 24, the same day that the U.S. Supreme Court overturned Roe v. Wade. Some fellow Republicans questioned the timing.

It certainly seemed like a convenient way to bury a veto of a bill that won support from the vast majority of Republicans in New Hampshire,” JR Hoell, co-founder of the conservative watchdog group RebuildNH, told The Epoch Times.

Hoell is a former four-term House Republican planning to seek re-election after a four-year hiatus from the the New Hampshire legislature.

Earlier this year, the New Hampshire Department of Children Youth and Family (DCYF) tried to take custody of Hoell’s 13-year old son after a nurse reported him for giving human-grade ivermectin to the teen months earlier.

Several states have introduced bills to make human-grade ivermectin available without a prescription at a brick and mortar store. Currently, it can be ordered online from another country. In April, Tennessee became the the first state to sign such a measure into law. New Hampshire lawmakers were first to introduce the idea.

Both chambers of the state’s Republican controlled legislature approved the bill.

In his statement explaining the veto, Sununu noted that there are only four other controlled medications available without a prescription in New Hampshire and that each were only made available after “rigorous reviews and vetting to ensure” before being dispensed.

“Patients should always consult their doctor before taking medications so that they are fully aware of treatment options and potential unintended consequences of taking a medication that may limit other treatment options in the future,” Sununu said in his statement.

Sununu’s statement is very similar to testimony given by Paula Minnehan, senior vice president of state government regulations for the New Hampshire Hospital Association, at hearings on the bill.

Minnehan too placed emphasis on the review that went into the four prescription medications the state made available under a standing order. They include naloxone, the generic name for Narcan, which is used to counter opioid overdoses, hormone replacement therapy drugs, and a prescription-version of the morning after pill.

It also includes a collection of smoking cessation therapy drugs like Chantix, which has been linked to suicide, depression, and other neuropsychiatric conditions. Last year, Pfizer, the leading maker of the FDA-approved drug, conducted a voluntarily recall of Chantix. Narcan has also been linked to deaths caused by severe withdrawals that have led to acute respiratory distress.

Rep. Melissa Blasek, a Republican co-sponsor of the New Hampshire ivermectin bill, told The Epoch Times, that one could veto any drug-related bill under the pretense of overdose concerns.

The reality is you can overdose on Tylenol,” she said. “Ivermectin has one of the safest track records of any drug.”

The use of human-grade ivermectin became controversial when some doctors began promoting it for the treatment and prevention of COVID-19. Government agencies including the FDA and CDC issued warnings against its use while groups like Front Line COVID-19 Critical Care Alliance (FLCCC) heavily promoted it.

Some doctors were  disciplined for prescribing human-grade ivermectin for COVID-19 including a Maine doctor whose medical license was suspended by the state.

Read more here...

Tyler Durden Thu, 06/30/2022 - 20:30

Read More

Continue Reading

Spread & Containment

Aging-US | Time makes histone H3 modifications drift in mouse liver

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone…

Published

on

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone H3 modifications drift in mouse liver.”

Credit: Hillje et al.

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone H3 modifications drift in mouse liver.”

Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.

“So far, no study discloses any drift of histone marks in mammals which is time-dependent or influenced by pro-longevity caloric restriction treatment.”

To detect the epigenetic drift of time passing, researchers—from Istituto di Ricovero e Cura a Carattere Scientifico, University of Urbino ‘Carlo Bo’, University of Milan, and University of Padua—determined the genome-wide distributions of mono- and tri-methylated lysine 4 and acetylated and tri-methylated lysine 27 of histone H3 in the livers of healthy 3, 6 and 12 months old C57BL/6 mice. 

“In this study, we used chromatin immunoprecipitation sequencing technology to acquire 108 high-resolution profiles of H3K4me3, H3K4me1, H3K27me3 and H3K27ac from the livers of mice aged between 3 months and 12 months and fed 30% caloric restriction diet (CR) or standard diet (SD).”

The comparison of different age profiles of histone H3 marks revealed global redistribution of histone H3 modifications with time, in particular in intergenic regions and near transcription start sites, as well as altered correlation between the profiles of different histone modifications. Moreover, feeding mice with caloric restriction diet, a treatment known to retard aging, reduced the extent of changes occurring during the first year of life in these genomic regions.

“In conclusion, while our data do not establish that the observed changes in H3 modification are causally involved in aging, they indicate age, buffered by caloric restriction, releases the histone H3 marking process of transcriptional suppression in gene desert regions of mouse liver genome most of which remain to be functionally understood.”

DOI: https://doi.org/10.18632/aging.204107 

Corresponding Author: Marco Giorgio – marco.giorgio@unipd.it 

Keywords: epigenetics, aging, histones, ChIP-seq, diet

Sign up for free Altmetric alerts about this article:  https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.204107

About Aging-US:

Launched in 2009, Aging (Aging-US) publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

Follow Aging on social media: 

  • SoundCloud – https://soundcloud.com/Aging-Us
  • Facebook – https://www.facebook.com/AgingUS/
  • Twitter – https://twitter.com/AgingJrnl
  • Instagram – https://www.instagram.com/agingjrnl/
  • YouTube – https://www.youtube.com/agingus​
  • LinkedIn – https://www.linkedin.com/company/aging/
  • Pinterest – https://www.pinterest.com/AgingUS/

For media inquiries, please contact media@impactjournals.com.

Aging (Aging-US) Journal Office
6666 E. Quaker Str., Suite 1B
Orchard Park, NY 14127
Phone: 1-800-922-0957, option 1

###


Read More

Continue Reading

Trending