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Colossal Biosciences joins BioRescue in its mission to save the Northern White Rhino from extinction

With only two living females left, the partnership will contribute to the genetic recovery of the northern white rhino from complete extinction. Colossal…



With only two living females left, the partnership will contribute to the genetic recovery of the northern white rhino from complete extinction. Colossal developed a pioneering toolkit for the challenging task to restore genetic diversity from museal specimens for a living population of critically endangered species.  

Credit: photo: Steven Seet/Leibniz-IZW

With only two living females left, the partnership will contribute to the genetic recovery of the northern white rhino from complete extinction. Colossal developed a pioneering toolkit for the challenging task to restore genetic diversity from museal specimens for a living population of critically endangered species.  

Colossal Biosciences (“Colossal”), the world’s first de-extinction company, has teamed up with BioRescue, a consortium initiating and leading the scientific rescue mission of the northern white rhino employing advanced assisted reproduction technologies and stem cell associated techniques. The partnership will develop a roadmap for future rescue missions of endangered species using the world leading expertise of both organisations.

Together they will work to improve, develop and implement strategies in the fields of wildlife conservation research and wildlife veterinary medicine, providing approaches to reduce the sixth mass extinction.

The northern white rhino (Ceratotherium simum cottoni) is considered to be functionally extinct in the wild as a direct result of poaching. Its natural habitats include parts of Uganda, Chad, Sudan, the Central African Republic and the Democratic Republic of Congo. All these areas were completely emptied out of this charismatic megavertebrate more than a decade ago. The only two living females were born in the Czech ZOO Dvůr Králové and are being cared for at Ol Pejeta Conservancy in Kenya since 2009.

Prof. Dr. Thomas Hildebrandt, Project Head at BioRescue, Head of the Department of Reproduction Management of the Leibniz Institute for Zoo and Wildlife Research, and Member of the Scientific Advisory Board of Colossal, has spent over 25 years on a mission to save the northern white rhino species. He has led the efforts with BioRescue to convey how synthetic biology can be used in addition to the genetic rescue techniques that are already in place. “The northern white rhino is the world’s rarest large mammal and thousands of species are interlinked to its existence,” says Hildebrandt.  “With Colossal’s advanced genetic technology, we will be able to piece together the missing links of the species’ genetic history. Following decades of assisted reproduction and stem cell innovations made by scientists and conservationists, I’m thrilled that the partnership between Colossal and BioRescue will help to establish a sustainable and genetically robust northern white rhino population.”

The new partnership will assess the genetic diversity of the northern white rhino (Ceratotherium simum cottoni) in historic samples as the basis for ethically evaluated decisions on possibly enhancing the genetic variability of a future northern white rhino population. This ground breaking conservation strategy is accompanied by exemplary transparency of the project’s undertakings to the general public.

The Science Behind the Conservation

Colossal will assist the rescue mission by leveraging genome sequencing and gene editing methods to save the endangered species. The focus on the edits will be to improve genetic diversity in living cells and mitigate impacts of disease or lost adaptability to the changing climate.

  • Sequencing: The partnership will generate a global catalog of museum samples of northern white rhino specimens from the past, including bones, dry skin, and preserved organs and fetuses, which can be used to extract ancient DNA. The partners will then obtain preserved samples in order to sequence all suitable samples and study the genetic diversity of the species. 
  • Genetic Editing: Once loss to gene pools has been identified in preserved specimens, Colossal will use the identified sequences as targets to restore the lost diversity into cell lines that will be used to produce northern white rhino embryos.
  • Population Study: The team will conduct a population study of genetic diversity of the southern white rhino (Ceratotherium simum simum) which is the sister taxon of the northern white rhino to identify key aspects of a healthy population. Colossal will leverage FormBio, its technology spinoff, to complete this study.  FormBio’s comparative genomic tool allows scientists to compare the DNA and genome of the specimens to the northern white rhino population we have today and identify genetic diversity that existed before the massive decline of the species. 

“We’re very honored to be BioRescue’s genetic rescue partner and thus have the opportunity to help save the northern white rhino, as well as other iconic keystone species from the brink of extinction,” says Ben Lamm, CEO and Co-Founder of Colossal. “At Colossal we’re passionate about species preservation and as part of our larger de-extinction work, we want to leverage our techniques and toolkit for conservation.  We are creating tools that will allow us to heal what has been lost and restore ecosystems that will be sustainable for future generations.”

The Conservation Paradox

The rate at which species loss is occurring is significantly faster than the restoration efforts of the classical conservation approaches. Between now and 2050, humanity will lose up to 50% of all biodiversity if nothing changes. The vast majority of conservation efforts are focused on preserving landscapes and ending poaching. But, with only two remaining northern white rhinos, the need to add more advanced technologies to preserve the taxon becomes apparent. In order to stop the loss, there is a need for new tools and technologies. The partnership is developing these tools to improve the capacity of the conservation ecosystem. 

“We’re really thankful to Prof Dr. Hildebrandt and BioRescue for trusting us as a partner to provide de-extinction technologies for the rescue of the northern white rhino,” says Matt James, Head of Conservation and Colossal’s Chief Animal Officer. “De-extinction is an engine of innovation that leads to tools that are directly applicable to conservation. Together, with some of the leading people in their fields, we will successfully be able to address and remedy specific conservation problems – starting with the northern white rhino.”

Colossal and BioRescue’s partnership is the starting point for future modern conservation networks which will help improve international conservation and conservation research organizations.

“The BioRescue Consortium is a unique model of extensive international cooperation that involves top scientists from Germany, Japan and Italy, conservationists in the field in Africa as well as zoo experts from Europe. This new partnership with Colossal transforms existing conservation approaches to a new level and can serve as a blueprint for other international efforts to save endangered species,” says Jan Stejskal, Director of International Projects at Dvůr Králové and coordinator of efforts to save the northern white rhinos.

Colossal’s Conservation Toolkit

Colossal’s conservation toolkit is a set of resources the company employs to help partner organizations preserve and save species at-risk. The company utilizes its expertise to preserve lost genetic diversity and create the hardware necessary for species rebirth and restoration to improve today’s conservation efforts. Now, Colossal will also provide these services as the synthetic genomic arm of BioRescue.



Colossal was founded by emerging technology and software entrepreneur Ben Lamm and world-renowned geneticist and serial biotech entrepreneur George Church, Ph.D.  Colossal creates disruptive technologies for extinct species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth.  Colossal is accepting humanity’s duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition through cutting-edge science and technologies. To follow along, please visit:


The BioRescue Consortium combines assisted reproduction technologies (ART) and stem cell associated techniques (SCAT) to save the northern white rhino from extinction. With the support of international partners the consortium aims to develop new scientific conservation approaches to preserve keystone and umbrella species. This will lead to blueprints which can be used in by conservation initiatives worldwide to halt the loss of biodiversity and preserve ecosystem services for future generations. The Consortium is led by German the Leibniz Institute for Zoo (Leibniz-IZW). Consortium members: Leibniz-IZW, the ZOO DVůR KRÁLOVÉ (Czech Republic), Avantea (Italy), Max Delbruck Centre for Molecular Medicine (Germany), Osaka University (Japan), and Padua University (Italy).



The Leibniz-IZW is an internationally renowned German research institute of the Forschungsverbund Berlin e.V. and a member of the Leibniz Association. Our mission is to examine evolutionary adaptations of wildlife to global change and develop new concepts and measures for the conservation of biodiversity. To achieve this, our scientists use their broad interdisciplinary expertise from biology and veterinary medicine to conduct fundamental and applied research – from molecular to landscape level – in close dialogue with the public and stakeholders. Additionally, we are committed to unique and high-quality services for the scientific community.



ZOO Dvůr Králové is a safari park in the Czech Republic. It’s one of the best rhino breeders outside of Africa and the only place where the northern white rhino bred in human care – both remaining females, Najin and Fatu, were born here. ZOO Dvůr Králové coordinates efforts to save the northern white rhinos.

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Which New World Order Are We Talking About?

Which New World Order Are We Talking About?

Authored by Jeff Thomas via,

Those of us who are libertarians have a tendency…



Which New World Order Are We Talking About?

Authored by Jeff Thomas via,

Those of us who are libertarians have a tendency to speak frequently of “the New World Order.”

When doing so, we tend to be a bit unclear as to what the New World Order is.

Is it a cabal of the heads of the world’s governments, or just the heads of Western governments?

Certainly bankers are included somewhere in the mix, but is it just the heads of the Federal Reserve and the IMF, or does it also include the heads of JPMorgan, Goldman Sachs, etc.?

And how about the Rothschilds? And the Bundesbank—surely, they’re in there, too?

And the list goes on, without apparent end.

Certainly, all of the above entities have objectives to increase their own power and profit in the world, but to what degree do they act in concert? Although many prominent individuals, world leaders included, have proclaimed that a New World Order is their ultimate objective, the details of who’s in and who’s out are fuzzy. Just as fuzzy is a list of details as to the collective objectives of these disparate individuals and groups.

So, whilst most libertarians acknowledge “the New World Order,” it’s rare that any two libertarians can agree on exactly what it is or who it’s comprised of. We allow ourselves the luxury of referring to it without being certain of its details, because, “It’s a secret society,” as evidenced by the Bilderberg Group, which meets annually but has no formal agenda and publishes no minutes. We excuse ourselves for having only a vague perception of it, although we readily accept that it’s the most powerful group in the world.

This is particularly true of Americans, as Americans often imagine that the New World Order is an American construct, created by a fascist elite of US bankers and political leaders. The New World Order may be better understood by Europeans, as, actually, it’s very much a European concept—one that’s been around for quite a long time.

It may be said to have had its beginnings in ancient Rome. As Rome became an empire, its various emperors found that conquered lands did not automatically remain conquered. They needed to be managed—a costly and tedious undertaking. Management was far from uniform, as the Gauls could not be managed in the same manner as the Egyptians, who in turn, could not be managed like the Mesopotamians.

After the fall of Rome, Europe was in many ways a shambles for centuries, but the idea of “managing” Europe was revived with the Peace of Westphalia in 1648. The peace brought an end to the Thirty Years’ War (1618-1648) in the Holy Roman Empire and the Eighty Years’ War (1568-1648) between Spain and the Dutch Republic. It brought together the Holy Roman Empire, The House of Habsburg, the Kingdoms of Spain and France, the Dutch Republic, and the Swedish Empire.

Boundaries were set, treaties were signed, and a general set of assumptions as to the autonomy within one’s borders were agreed, to the partial satisfaction of all and to the complete satisfaction of no one… Sound familiar?

Later, Mayer Rothschild made his name (and his fortune) by becoming the financier to the military adventures of the German Government. He then sent his sons out to England, Austria, France, and Italy to do the same—to create a New World Order of sorts, under the control of his family through national debt to his banks. (Deep Throat was right when he said, “Follow the Money.”)

So, the concept of a New World Order has long existed in Europe in various guises, but what does this tell us about the present and, more important, the future?

In our own time, we have seen presidents and prime ministers come and go, whilst their most prominent advisors, such as Henry Kissinger and Zbigniew Brzezinski, continue from one administration to the next, remaining advisors for decades. Such men are often seen as the voices of reason that may be the guiding force that brings about a New World Order once and for all.

Mister Brzezinski has written in his books that order in Europe depends upon a balance with Russia, which must be created through the control of Ukraine by the West. He has stated repeatedly that it’s critical for this to be done through diplomacy, that warfare would be a disaster. Yet, he has also supported the US in creating a coup in Ukraine. When Russia became angered at the takeover, he openly supported American aggression in Ukraine, whilst warning that Russian retaliation must not be tolerated.

Henry Kissinger, who has literally written volumes on his “pursuit of world peace” has, when down in the trenches, also displayed a far more aggressive personality, such as his angry recommendation to US President Gerald Ford to “smash Cuba” when Fidel Castro’s military aid to Angola threatened to ruin Mr. Kissinger’s plans to control Africa.

Whilst the most “enlightened” New World Order advisors may believe that they are working on the “Big Picture,” when it comes down to brass tacks, they clearly demonstrate the same tendency as the more aggressive world leaders, and reveal that, ultimately, they seek to dominate. They may initially recommend diplomacy but resort to force if the other side does not cave to “reason” quickly.

If we stand back and observe this drama from a distance, what we see is a theory of balance between the nations of Europe (and, by extension, the whole world)—a balance based upon intergovernmental agreements, allowing for centralised power and control.

This theory might actually be possible if all the countries of the world were identical in every way, and the goals of all concerned were also identical. But this never has been and can never be the case. Every world leader and every country will differ in its needs and objectives. Therefore, each may tentatively agree to common conditions, as they have going back to the Peace of Westphalia, yet, even before the ink has dried, each state will already be planning to gain an edge on the others.

In 1914, Europe had (once again) become a tangle of aspirations of the various powers—a time bomb, awaiting only a minor incident to set it off. That minor incident occurred when a Serbian national assassinated an Austrian crown prince. Within a month, Europe exploded into World War. As Kissinger himself has observed in his writings, “[T]hey all contributed to it, oblivious to the fact that they were dismantling an international order.”

Since 1648, for every Richelieu that has sought to create a New World Order through diplomacy, there has been a Napoleon who has taken a militaristic approach, assuring that the New World Order applecart will repeatedly be upset by those who are prone to aggression.

Further, even those who seek to operate through diplomacy ultimately will seek aggressive means when diplomatic means are not succeeding.

A true world order is unlikely.

What may occur in its stead would be repeated attempts by sovereign states to form alliances for their mutual benefit, followed by treachery, one- upmanship, and ultimately, aggression. And very possibly a new World War.

But of one thing we can be certain: Tension at present is as great as it was in 1914. We are awaiting only a minor incident to set off dramatically increased international aggression. With all the talk that’s presently about as to a New World Order, what I believe will occur instead will be a repeat of history.

If this belief is correct, much of the world will decline into not only external warfare, but internal control. Those nations that are now ramping up into police states are most at risk, as the intent is already clearly present. All that’s needed is a greater excuse to increase internal controls. Each of us, unless we favour being engulfed by such controls, might be advised to internationalise ourselves—to diversify ourselves so that, if push comes to shove, we’re able to get ourselves and our families out of harm’s way.

*  *  *

Unfortunately, there’s little any individual can practically do to change the course of these trends in motion. The best you can and should do is to stay informed so that you can protect yourself in the best way possible, and even profit from the situation. That’s precisely why bestselling author Doug Casey just released Surviving and Thriving During an Economic Collapse an urgent new PDF report. It explains what could come next and what you can do about it so you don’t become a victim. Click here to download it now.

Tyler Durden Wed, 10/04/2023 - 03:30

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As yen weakens and interest peaks, Bank of Japan balances on a policy precipice

Quick Take The Bank of Japan (BOJ) stands at a critical juncture, striving to maintain a delicate balance amid a changing economic landscape. Recent data…



Quick Take

The Bank of Japan (BOJ) stands at a critical juncture, striving to maintain a delicate balance amid a changing economic landscape. Recent data shows that the 10-year yield, which the BOJ has endeavored to keep below 1%, has touched 0.8, a peak unseen since 2013. Simultaneously, the BOJ has labored not to let the Yen weaken, yet it continues to be pressured as it drops further against the US dollar, crossing the 150 mark for the first time in over a year.

There is burgeoning speculation about possible BOJ interventions in these market movements. As the central bank continues to uphold negative interest rates, a shift towards positive rates might become inevitable in the foreseeable future. It’s a precarious fulcrum of financial strategies that the BOJ is balancing on, with market tempests stirring on one side and the stability of the national currency on the other.

This scenario highlights the intricate dynamics of monetary policies and the profound impact they can have on both national and global economies. A closer look at the situation illuminates the complexities in the BOJ’s policy decisions and the broader implications on the financial landscape.

JPY: (Source: Trading View)

The post As yen weakens and interest peaks, Bank of Japan balances on a policy precipice appeared first on CryptoSlate.

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Poland, Austria, & Czechia Introduce Temporary Border-Checks With Slovakia To Curb Illegal Migration

Poland, Austria, & Czechia Introduce Temporary Border-Checks With Slovakia To Curb Illegal Migration

Authored by Thomas Brooke via Remix…



Poland, Austria, & Czechia Introduce Temporary Border-Checks With Slovakia To Curb Illegal Migration

Authored by Thomas Brooke via Remix News,

Poland, Austria and Czechia will all introduce random checks at the countries’ borders with Slovakia from midnight on Wednesday following an influx of illegal immigration.

Temporary checks will be conducted along the length of the border for an initial 10-day period until Oct. 13.

They will focus specifically on road and railway border crossings, although, pedestrians and cyclists may also be asked for documentation. Anyone within the vicinity of the border may be requested to identify themselves.

“The numbers of illegal migrants to the EU are starting to grow again,” said Czech Prime Minister Petr Fiala following the announcement. “We don’t take the situation lightly.”

“Citizens need a valid passport or identity card to cross the border,” the Czech Interior Ministry added.

The Czech policy would also be adopted by neighboring Austria, the country’s Interior Minister Gerhard Karner confirmed.

Poland had already announced its intention to reintroduce checks on the Slovak border with the number of migrants along the Balkans migration route continuing to surge. Prime Minister Mateusz Morawiecki said last week he was “instructing Minister of Interior Mariusz Kamiński to check on buses, coaches, and cars crossing the border when it is suspected there could be illegal migrants on board.”

“In recent weeks, we detected and detained 551 illegal migrants at the border with Slovakia. This situation causes us to take decisive action,” Kaminski added.

Slovak caretaker Prime Minister Ludovit Odor acknowledged the growing issue of illegal migration in his country but insisted that the problem needs a European solution rather than individual nations restricting border access.

He claimed that the decision by the three neighboring countries had been fueled by the Polish government, which is involved in a tightly contested election campaign, with Poles heading to voting booths on Oct. 15.

“The whole thing has been triggered by Poland, where an election will soon take place, and the Czech Republic has joined in,” Odor said.

Slovakia revealed last month that the number of illegal migrants detained by its authorities this year had soared nine-fold to over 27,000. The majority of detainees comprise young men from the Middle East using the Balkan migratory route through Serbia as they seek to migrate to northwestern Europe.

The winner of Sunday’s general election in Slovakia, former Prime Minister Robert Fico, has vowed to tackle the issue more robustly by promising to reintroduce border checks with neighboring Hungary.

“It will not be a pretty picture,” Fico told journalists as he threatened to use force to dispel illegal migrants detected on Slovak territory.

Tyler Durden Wed, 10/04/2023 - 02:00

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