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Chronic Shortages Of A Few Items Now Will Evolve Into Chronic Shortages Of Hundreds Of Products Later In 2022

Chronic Shortages Of A Few Items Now Will Evolve Into Chronic Shortages Of Hundreds Of Products Later In 2022

Authored by Michael Snyder via…

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Chronic Shortages Of A Few Items Now Will Evolve Into Chronic Shortages Of Hundreds Of Products Later In 2022

Authored by Michael Snyder via TheMostImportantNews.com,

What we have witnessed so far is just the beginning of the story.  The global response to the COVID pandemic during 2020 and 2021 created the most epic supply chain crisis in modern times, and now “black swan events” such as the war in Ukraine and the bird flu pandemic are making that supply chain crisis even worse.  Unfortunately, more global difficulties are coming.  There will be more war, there will be more pestilences, there will be more natural disasters, and even the United Nations is admitting that we are heading into the worst global food crisis since World War II.  So if you think that global supply chain problems are severe now, just wait until you see what is coming next.

If you go into most major retailers today, you will notice that stock levels are lower than usual and there are some empty shelves.

But most items are still available most of the time, and that is good news.

Of course there are certain product categories that have been experiencing chronic shortages for an extended period of time.  For example, supplies of canned pet food have been extremely tight for months on end

The next time you go to the pet store don’t be surprised to see some empty shelves.

Many pet stores are facing a shortage on canned pet food.

Right now, there just aren’t enough cheap sources of chicken and turkey due to the bird flu pandemic, there is an ongoing shortage of aluminum, and there is a shortage of factory workers.

So the canned pet food shortage is not likely to be fixed any time soon.

Another shortage that is going to affect much of the country as we head into the summer months is the growing chlorine shortage.

I was not even aware of this shortage until a reader alerted me.  Apparently this shortage was originally caused by the destruction of a manufacturing facility in Louisiana by Hurricane Laura…

While the pandemic takes its share of the blame, the even larger reason for the current chlorine shortage is that a major chlorine manufacturing plant in Louisiana was destroyed by Hurricane Laura in late 2020. A fire on the premises leveled the facilities and took nearly 40% of the country’s chlorine tablet supply with it.

The manufacturing plant is being rebuilt and is currently under construction; it was due to reopen by mid-to-late 2022, but those plans could be pushed back due to the ongoing construction material shortages.

I find it ironic that the nationwide chlorine shortage could be extended thanks to the nationwide construction material shortage.

Anyone that is trying to build a home knows how painful the construction material shortage has become, and I anticipate that it will only become more severe in 2023 and beyond.

Meanwhile, the nationwide baby formula shortage just continues to get even worse

Janis Burnson is one of many parents having to work around a national baby formula shortage.

“Go around in our area, St. George, any stores I can, can’t find anything around here. I have friends in northern Utah, they’re having to send me stuff, so I’m having to pay even more,” she says.

One local reporter in southern Utah decided to check this out for herself, and when she visited local stores she discovered “bare shelves where baby formula should be.”

What a nightmare.

But at least we can be glad that things are not as bad here as they are in Europe.

Over there, widespread rationing of certain products has already begun.  For example, it was just announced that Tesco is now limiting each customer to three bottles of cooking oil

If record-high food prices weren’t enough. The Russia-Ukraine conflict has choked off the world of sunflower oil supply, forcing the largest supermarket in the UK to begin rationing.

The Guardian reports that Tesco, with more than 4,000 retail stores, placed buying limits of three cooking oil bottles per customer. It follows Waitrose and Morrisons, other supermarket chains that set limits of just two per customer.

This particular shortage is directly related to the war in Ukraine, and David Einhorn is warning that this war is making a whole host of our ongoing problems even worse…

The common refrain about COVID was that it sped up changes and trends that were already happening. We believe the same is true of the war. Inflation, supply chain problems, and shortages of energy, food, raw materials and labor were already issues that the war has now accelerated. 

Sadly, he is quite correct, and at this point there appears to be no hope that this war will end any time soon.

Russia and Ukraine normally account for approximately 30 percent of all global wheat exports, and we were already facing an unprecedented global food crisis even before the war erupted.

When U.S. Senator Roger Marshall was recently asked about this, he openly admitted that a “worldwide famine” is definitely going to happen…

“Did you just say there will be a famine in Europe in the next two years?” Host Maria Bartiromo asked.

“This will be a worldwide famine. I think it will be even worse next year than this year. So if 12, 15% of the wheat comes from Ukraine that’s exported, and they’re having problems getting fertilizer, they’re having tractors in the field, all the diesel fuel is going towards their war efforts, right?” the senator said.

Prior to 2022, can you ever remember a time when a sitting member of the U.S. Senate publicly warned us that a “worldwide famine” was coming?

The good news is that nobody is starving to death in the United States right now.

But food prices are certainly going up dramatically, and the mainstream media is doing lots of stories about it.  For example, the following originally comes from USA Today

Kevin Tave stretches a pot of spaghetti for three days of meals. Esmerelda Cortez gets eggs and bread from the food bank so she can afford laundry detergent at the store. Donnie Whitfield buys generic cereal instead of the Kellogg’s he prefers.

Although unemployment continues dropping and wages are on the rise, all across the country, low-income people are struggling to put food on the table as skyrocketing inflation and high gas prices take a bigger bite of their already-small paychecks.

Needless to say, as conditions deteriorate it is not a good thing for Joe Biden’s approval ratings

During Joe Biden’s fifth quarter in office, which began on January 20 and ended on April 19, an average of 41.3% of U.S. adults approved of the job he was doing as president. The latest average is essentially unchanged from the 41.7% in his fourth quarter but significantly lower than his first three quarterly averages.

But what most Americans don’t understand is that it is too late for a political solution to this crisis.

No matter what Joe Biden and his minions decide to do, they are not going to be able to prevent the nightmarish conditions which are rapidly approaching.

As Senator Marshall admitted, there will be a worldwide famine.

There is no avoiding that now.

These are such troubled times, and they are only going to become even more troubled as the months roll along.

*  *  *

It is finally here! Michael’s new book entitled “7 Year Apocalypse” is now available in paperback and for the Kindle on Amazon.

Tyler Durden Wed, 04/27/2022 - 06:30

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University of Kentucky researchers develop online portal to show how biases in RNA sequences affect gene expression

LEXINGTON, Ky. (June 29, 2022) — A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding…

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LEXINGTON, Ky. (June 29, 2022) — A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.

Credit: Pete Comparoni | University of Kentucky Photo

LEXINGTON, Ky. (June 29, 2022) — A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences between tissues and cells alter gene expression without changing the underlying genetic code.

Introductory biology classes teach that DNA is transcribed into RNA, which is then translated into proteins. However, many cellular processes affect how quickly transcription and translation occur. Gene expression looks at the differences in RNA concentrations within a cell, and it can help scientists know which genes are active within that tissue or cell.

“Changes in gene expression can significantly affect various diseases and disease trajectories,” said Justin Miller, Ph.D., assistant professor in the UK College of Medicine’s Department of Pathology and Laboratory Medicine.

Miller, who is also affiliated with the Sanders-Brown Center on Aging and Biomedical Informatics, says he and his colleagues previously developed the first algorithm to identify ramp sequences from a single gene sequence. Through their recent work, Miller and fellow UK co-authors Mark Ebbert, Ph.D., and Matthew Hodgman created an online version of that algorithm and showed that ramp sequences change between tissues and cells without changing the RNA sequence.

A ramp sequence is part of the RNA sequence that slows translation at the beginning of the gene by using codons (sequences of three DNA or RNA nucleotides) that are not easily translated. Ramp sequences counterintuitively increase overall gene expression by evenly spacing the translational machinery and preventing collisions later in translation.

In their recent publication in NAR Genomics and Bioinformatics, the researchers present the first comprehensive analysis of tissue- and cell type-specific ramp sequences and report more than 3,000 genes with ramp sequences that change between tissues and cell types, which correspond with increased gene expression within those tissues and cells.

“This research is the first time that variable ramp sequences have been described. Our comprehensive web interface allows other researchers to creatively explore ramp sequences and gene expression,” said Miller.

The research team says this work is important because while there are multiple ways for our RNA to encode the same proteins, the specific RNA sequence is important to regulate protein and RNA levels.

“Essentially, a ramp sequence works like an on-ramp to a freeway so that ribosomes do not crash into each other, but the length and speed limit of that onramp can change depending on the cell and the available resources within that cell,” Miller explained.

He says he enjoyed working on this project not only with his colleagues at UK but as well as his former colleagues at Brigham Young University and his brother, Kyle Miller, at Utah Valley University. Together, the group created a web interface for people to see how ramp sequences correspond with human and COVID-19 gene expression in different tissues and cells.

Miller says he believes this work will eventually impact patient care. “We created an online interface for researchers to query all human genes and see if a specific gene has a ramp sequence in a given tissue and how that gene is expressed within that tissue,” said Miller. “We also show that various COVID-19 genes and human entry factors for COVID-19 have ramp sequences that change between different tissues. Ramp sequences are much more likely to occur in tissues where the virus is known to proliferate.”

So, the researchers believe that COVID-19 genes have genetic biases (ramp sequences) that allow them to use the available cellular machinery to increase their expression. “Our research may help us better predict which tissues and cells new viruses will infect and also provides a potential therapeutic target to regulate tissue-specific gene expression without changing the translated protein,” said Miller.

Research reported in this publication was supported by the National Institute on Aging of the National Institutes of Health under Award Numbers P30AG072946 and R01AG068331, and the National Institute of General Medical Sciences of the National Institutes of Health under Award Number R35GM138636. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

This work was also funded by the BrightFocus Foundation, under awards A2020118F and A2020161S, and the Alzheimer’s Association, under award 2019-AARG-644082.

The University of Kentucky is increasingly the first choice for students, faculty and staff to pursue their passions and their professional goals. In the last two years, Forbes has named UK among the best employers for diversity, and INSIGHT into Diversity recognized us as a Diversity Champion four years running. UK is ranked among the top 30 campuses in the nation for LGBTQ* inclusion and safety. UK has been judged a “Great College to Work for” three years in a row, and UK is among only 22 universities in the country on Forbes’ list of “America’s Best Employers.”  We are ranked among the top 10 percent of public institutions for research expenditures — a tangible symbol of our breadth and depth as a university focused on discovery that changes lives and communities. And our patients know and appreciate the fact that UK HealthCare has been named the state’s top hospital for five straight years. Accolades and honors are great. But they are more important for what they represent: the idea that creating a community of belonging and commitment to excellence is how we honor our mission to be not simply the University of Kentucky, but the University for Kentucky.


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White House Is Quietly Modeling For $200 Oil “Shock”

White House Is Quietly Modeling For $200 Oil "Shock"

While the Biden administration is hoping and praying that someone – anyone – will watch…

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White House Is Quietly Modeling For $200 Oil "Shock"

While the Biden administration is hoping and praying that someone - anyone - will watch the comical "Jan 6" kangaroo hearsay court taking place in Congress and meant to somehow block Trump from running for president in 2024 while also making hundreds of millions of Americans forget that the current administration could very well be the worst in US history, it is quietly preparing for the worst.

As none other than pro-Biden propaganda spinmaster CNN reports, when it comes to what really matters (at least according to Gallup), namely the economy, and specifically galloping gasoline prices, the White House is in a historic shambles.

For an administration that ended last year forecasting a leveling off of 40-year high inflation and eager to tout a historically rapid recovery from the pandemic-driven economic crisis, there is a level of frustration that comes with an acutely perilous moment. Asked by CNN about progress on a seemingly intractable challenge, another senior White House official responded flatly: "Which one?"

The suspects behind the historic implosion are well known: "soaring prices, teetering poll numbers and congressional majorities that appear to be on the brink have created no shortage of reasons for unease. Gas prices are hovering at or around $5 per gallon, plastered on signs and billboards across the country as a symbolic daily reminder of the reality -- one in which White House officials are extremely aware -- that the country's view of the economy is growing darker and taking Biden's political future with it."

"You don't have to be a very sophisticated person to know how lines of presidential approval and gas prices go historically in the United States," a senior White House official told CNN.

A CNN Poll of Polls average of ratings for Biden's handling of the presidency finds that 39% of Americans approve of the job he's doing. His numbers on the economy, gas prices and inflation specifically are even worse in recent polls. What CNN won't tell you is that Biden is now polling well below Trump at this time in his tenure.

The CNN article then goes into a lengthy analysis of what is behind the current gasoline crisis (those with lots of time to kill can read it here) and also tries to explains, without actually saying it, that the only thing that can fix the problem is more supply, but - as we first explained - this can't and won't happen because green fanatics and socialist environmentalists will never agree to boosting output.

Which brings us to the punchline: as CNN's Phil Mattingly writes, "instead of managing an economy in the midst of a natural rotation away from recovery and into a stable period of growth, economic officials are analyzing and modeling worst-case scenarios like what the shock of gas prices hitting $200 per barrel may mean for the economy."

Well, in an article titled "Give us a plan or give us someone to blame", this seems like both a plan, and someone to blame.

But unfortunately for Biden - and CNN which is hoping to reset expectations - it's only going to get worse, because as we noted moments ago, while nobody was paying attention, Cushing inventories dropped to just 1 million away from operational bottoms at roughly 20MM barrels. This means that the US is officially looking at tank bottoms.

But wait, there's more... or rather, it's even worse, because as even Bloomberg's chief energy guru Javier Blas notes, over the last 2 weeks, the US gov has drained 13.7 million barrels from the SPR, "and yet, commercial oil stockpiles still fell 3 million barrels over the period."

Just imagine, Blas asks rhetorically, "if the SPR wasn't there. Or what would happen post-Oct when sales end."

And here is the punchline: at the current record pace of SPR drainage, one way or another the Biden admin will have to end its artificial attempts to keep the price of oil lower some time in October (or risk entering a war with China over Taiwan with virtually no oil reserve). This means that unless Putin ends his war some time in the next 5 months, there is a non-trivial chance that oil will hit a record price around $200 - precisely the price the White House is bracing for - a few days before the midterms. While translates into $10+ gasoline.

And while one can speculate how much longer Democrats can continue the "Jan 6" dog and pony show as the entire economy implodes around them, how America will vote in November when gas is double digits should not be a mystery to anyone.

Tyler Durden Wed, 06/29/2022 - 13:05

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European Commission says it doesn’t have texts between president Ursula von der Leyen and Pfizer CEO Albert Bourla

Under fire from the European ombudsman, the Commission said on Wednesday that it hasn’t found any text messages between president Ursula von der Leyen…

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Under fire from the European ombudsman, the Commission said on Wednesday that it hasn’t found any text messages between president Ursula von der Leyen and Pfizer chief Albert Bourla regarding the purchase of Covid-19 vaccines.

The messages became of interest last April, when the New York Times reported that a series of texts and calls between von der Leyen and Bourla led to Pfizer’s largest vaccine deal — 900 million doses of the current vaccine and a vaccine adapted to variants, with the option to purchase an additional 900 million doses through 2023.

Emily O’Reilly

Upon a public access request made by a journalist, the EC responded that it had no record of them. However, it was later revealed by ombudsman Emily O’Reilly, the EU’s internal watchdog, that the EC never explicitly asked the cabinet to look for the texts.

Instead, the EC requested other documents that fall under its internal criteria for recording, which doesn’t include text messages.

O’Reilly accused the Commission of “maladministration,” and urged the administration to conduct a more thorough search.

“When it comes to the right of public access to EU documents, it is the content of the document that matters and not the device or form,” she said in a statement back in January. “If text messages concern EU policies and decisions, they should be treated as EU documents.”

On Wednesday, the EC claimed to side with O’Reilly: “The Commission and the Ombudsman agree that what matters is the content of a document,” a spokesperson said in an email to Endpoints News. 

However, the Commission maintained that the texts were not registered as documents “due to their short-lived and ephemeral nature.”

“Text and instant messages in general do not contain important information relating to policies, activities and decisions of the Commission, nor are they in the possession of the institution,” the EC shared in a letter.

The administration added that it intends to issue further guidance on the use of “modern communication tools” such as text and instant messages to clear up any confusion.

“The Ombudsman could equally be invited to participate in those discussions, if she wishes to do so,” the statement said.

Pfizer declined to comment on the content of the text messages.

Stella Kyriakides

The EC struck its third vaccine deal with Pfizer and BioNTech last May, after its other major supplier AstraZeneca ran into production issues and announced it would significantly reduce deliveries.

The contract, which called for up to 1.8 billion doses through 2023, also reserved the EU right to resell or donate doses to countries in need.

“We need to be one step ahead of the virus. This means having access to adapted vaccines to protect us against the threat of variants, booster vaccines to prolong immunity, as well as protecting our younger population,” commissioner for health and food safety Stella Kyriakides said at the time.

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