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Blockchain as One of the Goals of Digital Government Strategy in Brazil

Blockchain as One of the Goals of Digital Government Strategy in Brazil

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Advantages and challenges in the usage of blockchain in digital services provided by governments: Overview with a close look at Brazil.

In a recent trend survey made by DMEXCO and presented at an event in Cologne, Germany, it was determined that although the world is currently suffering economically, the digital economy may greatly benefit after the COVID-19 pandemic. According to the survey, the COVID-19 crisis will accelerate the rhythm of digital transformation.

One of the benefits of an advancing digital transformation is that it can lead to new solutions, unlocking inconceivable possibilities.

This is especially true in digital services provided by governments, as the potential for innovation within the sector is vast.

With that in mind, Brazil instituted its Digital Government Strategy through the Decree 10332/2020 this week.

Through the decree, the Brazilian government set guidelines for the transformation of digital services, the unification of digital channels, and the development of interoperability between systems.

Primary goals for Brazil’s digital government strategy:

  • Offering intuitive and straightforward public digital services, consolidated in a single platform.
  • Promoting the integration and interoperability of governmental databases.
  • Implementing the General Data law.
  • Making digital citizen identification available.
  • Optimizing information technology infrastructures.

The set goals fit perfectly in a blockchain structures context. Therefore, in the Annex to the Decree 10332 from April 28, the Brazilian government pointed to the use of blockchain as one of its goals for achieving the expansion of digital government services in Brazil.

“Initiative 8.3. Make, at least, nine datasets available in federal public administration via blockchain solution, until 2022.

Initiative 8.4. Implement resources for the creation of an interoperable Federal Government blockchain network, with the use of accurate identification and safe algorithms.”

In light of this development, this article will touch upon the exclusive functionalities of blockchain structures not found in other technologies that may benefit digital services provided by the government. Also, it will analyze why the use of blockchain adds value to public administration, the key benefits for citizens in the government’s use of blockchain, and the risks associated with the use of blockchain in the public sector. 

Moreover, this work will evaluate the areas of government that can benefit the most from the use of blockchain considering the current state of the technology, the controls that public managers should adopt when selecting a consensus algorithm, and whether the governments must opt to the use of permissioned, not-permissioned or hybrid blockchains.

In the end, we will analyze the controls best suited for public managers when utilizing oracle services in blockchain, the regulatory aspects that must be considered by public managers, and the main barriers that governments face when choosing decentralized and distributed solutions.

Exclusive advantages of blockchain/DLT structures not present in other technologies 

Blockchain structures solve the “double spending” issue, which refers to the fact that one can copy digital information using the internet. If, for example, a person transfers a digital asset through a representative document of car ownership to someone else, there is the risk of the sender delivering this document via the internet while still maintaining the original document of ownership.

Traditionally, this double-spending issue is lessened by third parties or trusted administrators, such as organizations, corporations and financial institutions, which act as a centralized authority for validating trust, controlling every transaction. 

As blockchain architecture has emerged, the responsibility of validating the real transfer of an asset to an entire network no longer falls on traditional trust validators or a centralized authority. So, the burden of confirming the actual shipment of an asset to the whole network has moved to carefully designed mathematical algorithms, also called consensus protocols.

This process virtually eliminates, or at least considerably reduces, the need for centralized trust validators and other intermediaries.

On blockchains, a value transfer is verified by the network via a consensus protocol that allows users of a peer-to-peer network to validate transactions and update the ledger in the entire network. The consensus protocol is tasked with establishing trust by ensuring that the value transfers made in the blockchain network are authentic and precise, unlike the traditionally established system where an intermediary or administrator in a centralized network is necessary.

It’s essential to note that there is no clear consensus in the definition of distributed ledger technology and blockchain technology, as I clarified in Chapter 1, Part 2 of Blockchain: Everything You Need to Know.

How does blockchain add value to the public sector? 

Blockchain can add value to the public administration sector on account of its immutable, transparent, trackable, trustworthy and operational resilience properties.

At the most basic level, its benefits include improved public services in ledger and information exchange processes.

Blockchain structures are an essential tool for reducing bureaucracy and corruption, protecting information, stopping fraudulent activities, promoting higher automation and trust from both civilians and companies in the governmental processes, as well as reducing costs for verification and network upkeep.

Verification costs comprise all the necessary fees to verify the attributes of a specific transaction without recurring additional expenses or performing an additional and expensive audit.

Network costs comprise all the workforce costs and capital necessary to guarantee that transactions happen in a traditional infrastructure.

Only public blockchains reduce network costs. Because of that, blockchain structures can reduce a large part of administrative tasks that the public administration performs in society today. With a blockchain protocol in place, a public administration may not have to provide storage and information exchange to facilitate its community’s economic activities. Instead, the administration can maintain the role of supervision concerning the transactions that happen in this infrastructure.

Blockchains provide more efficient public services by improving business processes for government actors at any level and fostering the creation of fast, cheap and — most importantly — safe public ledgers. 

Finally, it’s worth observing that blockchains are a general-purpose technology. That is, a nuclear technology whose amplitude of benefits cannot be measured in the current stage of its evolution.

Breakthrough technology such as the internet, blockchain, artificial intelligence, electric energy and others create benefits that perpetuate over time, impacting the global economy, industry, governments, corporations and the relationship between all of these and citizens. Electric energy, for example, is still finding new applications to this day.

Key benefits for citizens from the government’s use of blockchain

There are no benefits for citizens to be had when service providers and consumers have strongly differing levels of information on the same operation or transaction. This process wastes resources and discourages future contact.

Think of a situation where, when acquiring a product or service, you paid a much higher price than is customary in the market, or you didn’t have much information on the hired organization, which resulted in a different service than what you had sought. 

It is unlikely that you’ll return to buy from the same store or hire the same professional, because the higher the level of information asymmetry between organizations/companies and consumers, the less efficient the market is.

For a given market to thrive, service providers and users need to be able to trust the available information to decide if, how and when to make a transaction. It is here where citizens may benefit from the use of blockchain structures by the government.

Blockchains reduce the information asymmetry between service providers and consumers, facilitating beneficial deals. 

As blockchain infrastructures reduce transaction costs, they can make markets safer and more efficient while expanding the type of interactions and deals in which consumers are willing to participate.

Blockchain can improve the efficiency of markets by reducing verification costs and, in the case of public blockchains, network costs, as mentioned above.

The main risks related to the use of blockchain structures in the public sector

When it comes to risks, we can list the most important ones:

1) Immature standards

Because blockchain infrastructure is still maturing, the current lack of international standards poses risks for juridical, organizational and technological interoperability.

There must be guidelines regarding which technological standards to use for specific functions, and a certification body for blockchain infrastructures. There are international efforts in progress in these areas, including the Technical Committee ISO 307 on blockchain and distributed ledger technologies as well as work on the standardization sector of ITU ITU-T.

2) Protection of personal and sensitive data

The storage of consumers’ and users’ personal and sensitive data must occur outside of the blockchain network to harmonize the protection of its immutable and transparent data.

3) Dependency on complex algorithms

Are smart contracts and complex algorithms the new intermediary? If so, doesn’t the architecture for online platforms ultimately depend on specific choices made by their designers? If so, how much can we predict or even orchestrate the effects of these complex algorithms, and is doing so necessary to monitor the ethics and conduct of software code developers? Each of these questions — all still without an answer — is a challenge to overcome.

4) The oracles problem

Before smart contracts can do something beneficial, they need a trusted way of connecting to events in the real world. This has proven difficult so far. That is called “the oracles problem.”

Oracles are real-time data feeds that provide meteorological data, exchange rates, flight information and sporting stats to smart contracts.

The idea is that by oracles and smart contracts working together, both systems can allow for a blockchain-based service to interact with events in the real world with a broader level of confidence than is possible using today’s services. For instance, if your flight has been canceled but you bought flight insurance, a smart contract can be paid instantaneously after receiving an update from a trusted source.

The problem is that the oracles introduced so far conflict with the purpose of using a blockchain. Some oracles are too centralized — that is, they represent single points of failure that make them targets of cyber attacks.

This means that smart contracts cannot have trusted access to real-world data. This point will be returned to a little later, when we touch upon the controls that public managers need to adopt when utilizing oracle services in blockchain.

5) Reputation systems

In a decentralized network, it would be necessary to have sound reputation systems to decentralize decisions. This still is being developed.

Areas of government that can benefit the most from the use of blockchain

The management of government funds is an area where blockchain solutions can help minimize fraud and increase both transparency and accountability of involved entities.

Blockchain is perfect for trusted and traceable information auditing as well as simplifying the creation of platforms to be traced, when and where data was inserted, its use, who accessed it and so on.

This record-keeping quality of the tech dramatically improves transparency in terms of processing data and processes — essential in a regulatory environment — and hampers the improper use or falsification of information.

Considering the resources currently being spent on the verification and reconciliation of data collected by public administrations, the substantial savings in cost and time that can be achieved through blockchain is very compelling.

For example, we there is the United Kingdom’s Office of Science, which proposed many use cases of blockchain:

  1. Protecting critical infrastructures.
  2. Establishing new systems of payment for working benefits and pensions.
  3. Reinforcing international aid operations.
  4. Authentication of documents and smart contracts.
  5. Handling the European value-added tax.

Of those listed, blockchain’s use case for the authentication of documents such as certificates, licenses, intellectual ownership and patents, among others, is the most interesting in terms of short-term realization, considering the current stage of the technology.

In many countries, where corruption is a threat to the most common means of making profit — especially in the government — inviolable systems like blockchain architecture can bring significant benefits. For example, the government of Honduras recently began to collaborate with blockchain company Factom to use this technology for transmission of ownership titles in an effort to hinder corruption.

This example, among others, shows that blockchain technology — even though it has not yet reached its full maturity — is becoming increasingly comfortable to use. The open and global nature of public blockchains allows the tech’s structure to be available and accessible to every person, company and government, and the only requirement is a mobile network connection or internet access.

Some agencies and government bodies have realized the usefulness of blockchain for various types of transactions in which the government is involved, including how the government makes transactions and interacts with citizens and companies, particularly in complex environments with many stakeholders and high-volume transactions. 

How, where and how much value an adopted blockchain generates will depend on choices made by the government.

Digital transformation demands choices and strategic decisions that must be made in a programmed and planned fashion. Countries such as Singapore, China, Estonia, South Korea and others are already leading the way in this regard.

I see that Brazil needs to seize value with digital transformation, and blockchain can add that value. This breakthrough tech has the capacity to generate more efficient, transparent results and considerably reduce both fraud and costs. However, for that, the government must make a strategic choice as regards public policy, complete with medium- and long-term planning.

Controls that public managers should adopt when selecting a consensus algorithm

The consensus protocol is one of the leading technologies that make up blockchain architecture, along with cryptography and a peer-to-peer network. 

It is not recommended to choose a consensus protocol without considering the scope of the project. That is, not considering the intent behind using blockchain as a solution for a given problem or the set of all the other technologies that make up a blockchain.

When it comes to selecting a consensus protocol, a public manager must seek one that provides the following characteristics: agreement, collaboration, inclusion, participation, cooperation and equality. 

The controls that a public manager must adopt when selecting the most recommended consensus algorithm to a given project will depend case by case. Analyses will need to be run to answer questions like, “Does our data storage require extra measures to protect personal information?” and, “Are there expectations in the project about speed?” It is advisable to consult with a blockchain strategy expert to define the selection of blockchain architecture better suited for the project. We will come back to this topic later with an analysis of which types of blockchains are best adopted by governments — permissioned, public or hybrid.

Which types of blockchains should governments adopt — permissioned or public? What about hybrid blockchains?

Many governments will opt for hybrid blockchains, which benefit from combining both public and private (permissioned) blockchains.

Authoritarian governments such as China’s will prefer to use private blockchains.

Those looking to apply blockchain for innovation and significantly improve the lives of citizens will generally be democratic governments, countries where the use of blockchain is already advanced, and countries that have already adopted public blockchains, permissioned blockchains and hybrid blockchains.

In other words, the choice of a specific platform or infrastructure has been made by countries based on use case and initiative requirements.

Example of a public blockchain used by a government: The Republic of Georgia’s National Agency of Public Registry entered a partnership with Bitfury to provide its citizens with real estate records through a solution based on the Bitcoin protocol (a public blockchain).

Example of a private blockchain used by a government: The Swedish Mapping Cadastral and Land Registration Authority, Landshypotek Bank, SBAB, Telia, Chromaway and Kairos Future initiated a project in 2016 to redefine real estate transactions and mortgage actions. The goal is to approach problematic points in the current transaction system. The blockchain system is based on a private configuration.

Example of a hybrid blockchain used by a government: The Ministry of Education and Employment of Malta decided to use the open standard Blockcerts for the management of academic credentials. Blockcerts consists of libraries of public code, tools and mobile applications to create, store, share and verify personal, academic certificates. The private blockchain network is composed exclusively of certified institutions that are part of the ledger of academic documents using the Blockcerts solution. The standard also utilizes a public blockchain, as it anchors hashes from certificates in the Bitcoin blockchain.

It is essential to develop resilience in the networks so that the platforms and blockchain solutions can receive data, information and critical services. However, it is also crucial to count on professionals to design the blockchain project so it better meets objectives before making a choice as well as evaluating the project’s level of risk.

Finally, the question is not whether the potential of the technology is limited by the choice for a permissioned blockchain or not, because knowing which blockchain solution to adopt is necessary to answer questions like: “How restricted should reading access to transmitted network data be?” and, “Will there be automated processes between different entities?” and, “Is it necessary to program payment functionality?” and “Will the data storage require additional measures for protecting personal information?” and so on. 

It is essential to discover which type of adopted blockchain will genuinely meet the project or business model goals (not forgetting that private blockchains do not reduce network cost, only verification).

Which controls should a public manager adopt when utilizing oracle services in blockchain/DLT

Oracles are third-party services that are not part of a blockchain’s consensus mechanism.

The main challenge concerning oracles is that a public manager has to trust these sources of information. Be it a website or a sensor, the source of information must be believed.

Different trusted computing techniques can be used as a way of solving these problems.

Involving multiple sources of truth is an alternative and is likely safer, but also more expensive.

There is no single solution for everything, so the manager will need to search for and adopt applications with a risk-based approach to decide how many sources are necessary for different applications. 

For instance, the temperature in London can be retransmitted by a single oracle (like API) if it is used for a smartphone application, for which approximate precision is tolerated. But if the informed temperature is used to liquidate an insurance contract worth $10 million, it would be more judicious to involve multiple oracles: satellite data, local sensor data and so on.

The conclusion here is that a single, unaudited source is a weak link that could compromise the entire system that depends on it.

There are no foolproof systems, but public managers can apply the same concept of multiple barriers to decentralized oracles as mechanisms of trust minimization. 

Increasing the number of oracles lowers the probability of malicious conduct, thereby further securing the system. However, the risk of every oracle transmitting incorrect information, whether due to malicious activity or not (i.e., if the sources themselves are compromised), still exists.

Regulatory aspects that public managers need to consider when utilizing blockchain-based applications

Public managers must consider the following regulatory aspects in the utilization of applications based on blockchain/DLT:

  1. Finalization of liquidation and resolution of disputes, protecting consumers from risk.
  2. Responsibility for safety risks and associated losses, pushed by the introduction of new technological infrastructure.
  3. Protection against the risk of attack or dominance by a few “players,” as this can discourage potential users from linking assets outside the chain as well as regulations and antitrust implications.
  4. Conduct (priority in transaction verifications).
  5. Regulation and legal classification of assets, location and data flux, and how existing regulations apply.
  6. The implementation of data protection legislation, observing that many of these rules work extraterritorially, like the European law of data protection.

The main barriers to adoption of decentralized and distributed solutions for public administration 

Blockchain and other decentralized solutions generally face technical barriers such as scalability as well as other barriers that are legal or cultural in nature.

As an example of a legal barrier, Singapore carried out a proof-of-concept of a blockchain solution last year to combat money laundering with several banks. However, to be effective, the Know Your Customer and Anti-Money Laundering blockchain-based ledgers needed ubiquitous requirements and regulatory norms in member states. Unifying criteria and regulations on KYC and AML is something that regulators in Mercosur, for example, will have to solve.

For an architecture like blockchain, whose main objective is the transfer of value, questions of data protection are among the most relevant.

As for cultural barriers, the total transparency enabled by blockchain networks can raise concerns. Many participants in the market who are not used to this level of transparency may not feel comfortable with it at first. If “honest” market participants adopt this transparency (as it can drastically reduce its conformity costs), malicious actors may find themselves left with fewer places to hide. Because of that, the implementation of blockchain for governmental services will probably require the elimination of political and bureaucratic impediments.

Government structures, in which decisions can be affected by a change of politics and complicated rules of acquisition, represent additional obstacles. Aside from budgets for government projects generally being tight, government agencies are not immune to falling in step with administrators who are resistant to change or new mentalities, like in any large company.

Proof verification and pilot projects have both high and rising costs. It is often an expensive investment whose innovation many decision-makers in the public sector are not willing to pay for. I consider this a barrier relating to processing costs. 

Moreover, the costs for replacing existing, legacy infrastructure in any governmental organization with a new blockchain investment are very high. To add to this, the use of blockchain demands substantial changes in organizational procedures and responsibilities. We cannot underestimate the task of implementing blockchain. Planning, building and implementing complex IT systems is stressful in any sector.

Given the decentralized nature of blockchain, institutional barriers related to authority and governance can pose challenges to its adoption. This is primarily a management problem, at least in a fragmented and sectorial governmental structure, as costs and benefits are not intimately linked.

However, similarly to the construction of the internet, a large part of infrastructure costs must be covered centrally. At the same time, in other parts of governmental organizations and society as a whole, the benefits are palpable.

Particularly in Brazil, the small number of developers as well as the lack of digital education in the population is a challenge that increases the difficulty of transition from current systems to blockchain.

The views, thoughts and opinions expressed here are the author’s alone and do not necessarily reflect or represent the views and opinions of Cointelegraph.

Tatiana Revoredo is the chief strategy officer at Global Strategy, a specialist in blockchain strategies by the University of Oxford, a specialist in blockchain business application by MIT and a blockchain professor at Insper and Nextlaw Academy. She is also the author of the book, Cryptocurrencies in the International Scenario: What Is the Position of Central Banks, Governments and Authorities About Cryptocurrencies?

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Buried Project Veritas Recording Shows Top Pfizer Scientists Suppressed Concerns Over COVID-19 Boosters, MRNA Tech

Buried Project Veritas Recording Shows Top Pfizer Scientists Suppressed Concerns Over COVID-19 Boosters, MRNA Tech

Submitted by Liam Cosgrove

Former…

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Buried Project Veritas Recording Shows Top Pfizer Scientists Suppressed Concerns Over COVID-19 Boosters, MRNA Tech

Submitted by Liam Cosgrove

Former Project Veritas & O’Keefe Media Group operative and Pfizer formulation analyst scientist Justin Leslie revealed previously unpublished recordings showing Pfizer’s top vaccine researchers discussing major concerns surrounding COVID-19 vaccines. Leslie delivered these recordings to Veritas in late 2021, but they were never published:

Featured in Leslie’s footage is Kanwal Gill, a principal scientist at Pfizer. Gill was weary of MRNA technology given its long research history yet lack of approved commercial products. She called the vaccines “sneaky,” suggesting latent side effects could emerge in time.

Gill goes on to illustrate how the vaccine formulation process was dramatically rushed under the FDA’s Emergency Use Authorization and adds that profit incentives likely played a role:

"It’s going to affect my heart, and I’m going to die. And nobody’s talking about that."

Leslie recorded another colleague, Pfizer’s pharmaceutical formulation scientist Ramin Darvari, who raised the since-validated concern that repeat booster intake could damage the cardiovascular system:

None of these claims will be shocking to hear in 2024, but it is telling that high-level Pfizer researchers were discussing these topics in private while the company assured the public of “no serious safety concerns” upon the jab’s release:

Vaccine for Children is a Different Formulation

Leslie sent me a little-known FDA-Pfizer conference — a 7-hour Zoom meeting published in tandem with the approval of the vaccine for 5 – 11 year-olds — during which Pfizer’s vice presidents of vaccine research and development, Nicholas Warne and William Gruber, discussed a last-minute change to the vaccine’s “buffer” — from “PBS” to “Tris” — to improve its shelf life. For about 30 seconds of these 7 hours, Gruber acknowledged that the new formula was NOT the one used in clinical trials (emphasis mine):


“The studies were done using the same volume… but contained the PBS buffer. We obviously had extensive consultations with the FDA and it was determined that the clinical studies were not required because, again, the LNP and the MRNA are the same and the behavior — in terms of reactogenicity and efficacy — are expected to be the same.

According to Leslie, the tweaked “buffer” dramatically changed the temperature needed for storage: “Before they changed this last step of the formulation, the formula was to be kept at -80 degrees Celsius. After they changed the last step, we kept them at 2 to 8 degrees celsius,” Leslie told me.

The claims are backed up in the referenced video presentation:

I’m no vaccinologist but an 80-degree temperature delta — and a 5x shelf-life in a warmer climate — seems like a significant change that might warrant clinical trials before commercial release.

Despite this information technically being public, there has been virtually no media scrutiny or even coverage — and in fact, most were told the vaccine for children was the same formula but just a smaller dose — which is perhaps due to a combination of the information being buried within a 7-hour jargon-filled presentation and our media being totally dysfunctional.

Bohemian Grove?

Leslie’s 2-hour long documentary on his experience at both Pfizer and O’Keefe’s companies concludes on an interesting note: James O’Keefe attended an outing at the Bohemian Grove.

Leslie offers this photo of James’ Bohemian Grove “GATE” slip as evidence, left on his work desk atop a copy of his book, “American Muckraker”:

My thoughts on the Bohemian Grove: my good friend’s dad was its general manager for several decades. From what I have gathered through that connection, the Bohemian Grove is not some version of the Illuminati, at least not in the institutional sense.

Do powerful elites hangout there? Absolutely. Do they discuss their plans for the world while hanging out there? I’m sure it has happened. Do they have a weird ritual with a giant owl? Yep, Alex Jones showed that to the world.

My perspective is based on conversations with my friend and my belief that his father is not lying to him. I could be wrong and am open to evidence — like if boxer Ryan Garcia decides to produce evidence regarding his rape claims — and I do find it a bit strange the club would invite O’Keefe who is notorious for covertly filming, but Occam’s razor would lead me to believe the club is — as it was under my friend’s dad — run by boomer conservatives the extent of whose politics include disliking wokeness, immigration, and Biden (common subjects of O’Keefe’s work).

Therefore, I don’t find O’Keefe’s visit to the club indicative that he is some sort of Operation Mockingbird asset as Leslie tries to depict (however Mockingbird is a 100% legitimate conspiracy). I have also met James several times and even came close to joining OMG. While I disagreed with James on the significance of many of his stories — finding some to be overhyped and showy — I never doubted his conviction in them.

As for why Leslie’s story was squashed… all my sources told me it was to avoid jail time for Veritas executives.

Feel free to watch Leslie’s full documentary here and decide for yourself.

Fun fact — Justin Leslie was also the operative behind this mega-viral Project Veritas story where Pfizer’s director of R&D claimed the company was privately mutating COVID-19 behind closed doors:

Tyler Durden Tue, 03/12/2024 - 13:40

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Association of prenatal vitamins and metals with epigenetic aging at birth and in childhood

“[…] our findings support the hypothesis that the intrauterine environment, particularly essential and non-essential metals, affect epigenetic aging…

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“[…] our findings support the hypothesis that the intrauterine environment, particularly essential and non-essential metals, affect epigenetic aging biomarkers across the life course.”

Credit: 2024 Bozack et al.

“[…] our findings support the hypothesis that the intrauterine environment, particularly essential and non-essential metals, affect epigenetic aging biomarkers across the life course.”

BUFFALO, NY- March 12, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 4, entitled, “Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort.”

Epigenetic gestational age acceleration (EGAA) at birth and epigenetic age acceleration (EAA) in childhood may be biomarkers of the intrauterine environment. In this new study, researchers Anne K. Bozack, Sheryl L. Rifas-Shiman, Andrea A. Baccarelli, Robert O. Wright, Diane R. Gold, Emily Oken, Marie-France Hivert, and Andres Cardenas from Stanford University School of Medicine, Harvard Medical School, Harvard T.H. Chan School of Public Health, Columbia University, and Icahn School of Medicine at Mount Sinai investigated the extent to which first-trimester folate, B12, 5 essential and 7 non-essential metals in maternal circulation are associated with EGAA and EAA in early life. 

“[…] we hypothesized that OCM [one-carbon metabolism] nutrients and essential metals would be positively associated with EGAA and non-essential metals would be negatively associated with EGAA. We also investigated nonlinear associations and associations with mixtures of micronutrients and metals.”

Bohlin EGAA and Horvath pan-tissue and skin and blood EAA were calculated using DNA methylation measured in cord blood (N=351) and mid-childhood blood (N=326; median age = 7.7 years) in the Project Viva pre-birth cohort. A one standard deviation increase in individual essential metals (copper, manganese, and zinc) was associated with 0.94-1.2 weeks lower Horvath EAA at birth, and patterns of exposures identified by exploratory factor analysis suggested that a common source of essential metals was associated with Horvath EAA. The researchers also observed evidence of nonlinear associations of zinc with Bohlin EGAA, magnesium and lead with Horvath EAA, and cesium with skin and blood EAA at birth. Overall, associations at birth did not persist in mid-childhood; however, arsenic was associated with greater EAA at birth and in childhood. 

“Prenatal metals, including essential metals and arsenic, are associated with epigenetic aging in early life, which might be associated with future health.”

 

Read the full paper: DOI: https://doi.org/10.18632/aging.205602 

Corresponding Author: Andres Cardenas

Corresponding Email: andres.cardenas@stanford.edu 

Keywords: epigenetic age acceleration, metals, folate, B12, prenatal exposures

Click here to sign up for free Altmetric alerts about this article.

 

About Aging:

Launched in 2009, Aging publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

Please visit our website at www.Aging-US.com​​ and connect with us:

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Click here to subscribe to Aging publication updates.

For media inquiries, please contact media@impactjournals.com.

 

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A beginner’s guide to the taxes you’ll hear about this election season

Everything you need to know about income tax, national insurance and more.

Cast Of Thousands/Shutterstock

National insurance, income tax, VAT, capital gains tax, inheritance tax… it’s easy to get confused about the many different ways we contribute to the cost of running the country. The budget announcement is the key time each year when the government shares its financial plans with us all, and announces changes that may make a tangible difference to what you pay.

But you’ll likely be hearing a lot more about taxes in the coming months – promises to cut or raise them are an easy win (or lose) for politicians in an election year. We may even get at least one “mini-budget”.

If you’ve recently entered the workforce or the housing market, you may still be wrapping your mind around all of these terms. Here is what you need to know about the different types of taxes and how they affect you.

The UK broadly uses three ways to collect tax:

1. When you earn money

If you are an employee or own a business, taxes are deducted from your salary or profits you make. For most people, this happens in two ways: income tax, and national insurance contributions (or NICs).

If you are self-employed, you will have to pay your taxes via an annual tax return assessment. You might also have to pay taxes this way for interest you earn on savings, dividends (distribution of profits from a company or shares you own) received and most other forms of income not taxed before you get it.

Around two-thirds of taxes collected come from people’s or business’ incomes in the UK.

2. When you spend money

VAT and excise duties are taxes on most goods and services you buy, with some exceptions like books and children’s clothing. About 20% of the total tax collected is VAT.

3. Taxes on wealth and assets

These are mainly taxes on the money you earn if you sell assets (like property or stocks) for more than you bought them for, or when you pass on assets in an inheritance. In the latter case in the UK, the recipient doesn’t pay this, it is the estate paying it out that must cover this if due. These taxes contribute only about 3% to the total tax collected.

You also likely have to pay council tax, which is set by the council you live in based on the value of your house or flat. It is paid by the user of the property, no matter if you own or rent. If you are a full-time student or on some apprenticeship schemes, you may get a deduction or not have to pay council tax at all.


Quarter life, a series by The Conversation

This article is part of Quarter Life, a series about issues affecting those of us in our 20s and 30s. From the challenges of beginning a career and taking care of our mental health, to the excitement of starting a family, adopting a pet or just making friends as an adult. The articles in this series explore the questions and bring answers as we navigate this turbulent period of life.

You may be interested in:

If you get your financial advice on social media, watch out for misinformation

Future graduates will pay more in student loan repayments – and the poorest will be worst affected

Selling on Vinted, Etsy or eBay? Here’s what you need to know about paying tax


Put together, these totalled almost £790 billion in 2022-23, which the government spends on public services such as the NHS, schools and social care. The government collects taxes from all sources and sets its spending plans accordingly, borrowing to make up any difference between the two.

Income tax

The amount of income tax you pay is determined by where your income sits in a series of “bands” set by the government. Almost everyone is entitled to a “personal allowance”, currently £12,570, which you can earn without needing to pay any income tax.

You then pay 20% in tax on each pound of income you earn (across all sources) from £12,570-£50,270. You pay 40% on each extra pound up to £125,140 and 45% over this. If you earn more than £100,000, the personal allowance (amount of untaxed income) starts to decrease.

If you are self-employed, the same rates apply to you. You just don’t have an employer to take this off your salary each month. Instead, you have to make sure you have enough money at the end of the year to pay this directly to the government.


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The government can increase the threshold limits to adjust for inflation. This tries to ensure any wage rise you get in response to higher prices doesn’t lead to you having to pay a higher tax rate. However, the government announced in 2021 that they would freeze these thresholds until 2026 (extended now to 2028), arguing that it would help repay the costs of the pandemic.

Given wages are now rising for many to help with the cost of living crisis, this means many people will pay more income tax this coming year than they did before. This is sometimes referred to as “fiscal drag” – where lower earners are “dragged” into paying higher tax rates, or being taxed on more of their income.

National insurance

National insurance contributions (NICs) are a second “tax” you pay on your income – or to be precise, on your earned income (your salary). You don’t pay this on some forms of income, including savings or dividends, and you also don’t pay it once you reach state retirement age (currently 66).

While Jeremy Hunt, the current chancellor of the exchequer, didn’t adjust income tax meaningfully in this year’s budget, he did announce a cut to NICs. This was a surprise to many, as we had already seen rates fall from 12% to 10% on incomes higher than £242/week in January. It will now fall again to 8% from April.


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While this is charged separately to income tax, in reality it all just goes into one pot with other taxes. Some, including the chancellor, say it is time to merge these two deductions and make this simpler for everyone. In his budget speech this year, Hunt said he’d like to see this tax go entirely. He thinks this isn’t fair on those who have to pay it, as it is only charged on some forms of income and on some workers.

I wouldn’t hold my breath for this to happen however, and even if it did, there are huge sums linked to NICs (nearly £180bn last year) so it would almost certainly have to be collected from elsewhere (such as via an increase in income taxes, or a lot more borrowing) to make sure the government could still balance its books.

A young black man sits at a home office desk with his feet up, looking at a mobile phone
Do you know how much tax you pay? Alex from the Rock/Shutterstock

Other taxes

There are likely to be further tweaks to the UK’s tax system soon, perhaps by the current government before the election – and almost certainly if there is a change of government.

Wealth taxes may be in line for a change. In the budget, the chancellor reduced capital gains taxes on sales of assets such as second properties (from 28% to 24%). These types of taxes provide only a limited amount of money to the government, as quite high thresholds apply for inheritance tax (up to £1 million if you are passing on a family home).

There are calls from many quarters though to look again at these types of taxes. Wealth inequality (the differences between total wealth held by the richest compared to the poorest) in the UK is very high (much higher than income inequality) and rising.

But how to do this effectively is a matter of much debate. A recent study suggested a one-off tax on total wealth held over a certain threshold might work. But wealth taxes are challenging to make work in practice, and both main political parties have already said this isn’t an option they are considering currently.

Andy Lymer and his colleagues at the Centre for Personal Financial Wellbeing at Aston University currently or have recently received funding for their research work from a variety of funding bodies including the UK's Money and Pension Service, the Aviva Foundation, Fair4All Finance, NEST Insight, the Gambling Commission, Vivid Housing and the ESRC, amongst others.

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